An intravascular imaging device is provided. In some embodiments, the intravascular imaging device includes a flexible elongate member sized and shaped for insertion into a vessel of a patient, the flexible elongate member having a proximal portion and a distal portion; and an imaging assembly disposed at the distal portion of the flexible elongate member, the imaging assembly including a flex circuit positioned directly around the flexible elongate member. In some embodiments, a method of assembling an intravascular imaging device includes obtaining a flex circuit including a first layer having a plurality of transducers and a second layer having an acoustic backing material; and positioning the flex circuit directly around a distal portion of a flexible elongate member.

An intraluminal ultrasound imaging device includes a flexible elongate member configured to be positioned within a body lumen of a patient. The flexible elongate member includes a proximal portion and a distal portion. The device also includes an ultrasound imaging assembly disposed at the distal portion of the flexible elongate member. The ultrasound imaging assembly is configured to obtain imaging data of the body lumen. The ultrasound imaging assembly includes a transducer array including a substrate, a silicon oxide layer disposed over the substrate, and a plurality of rows of micromachined ultrasound transducer elements disposed on the silicon oxide layer. Two of the plurality of rows of micromachined ultrasound transducer elements are spaced apart by a trench formed by etching through a screen formed in the silicon oxide layer. Associated devices, systems, and methods are also provided.

Ultrasound transducer element arrays using acoustic ensonification drive patterns via a patient interface for sonosensitizer activation in sonodynamic therapy. Incoherent acoustic field generation varying phase, frequencies, and/or amplitude via controlled delivery of low intensity planar acoustic waves. Method includes generating a first and a second signal to generate respective acoustic ensonification drive patterns with phase, frequency, and amplitude and generating at least one relative phase, frequency or amplitude difference to generate a third incoherent acoustic ensonification pattern to activate a sonosensitizer. Calibration and complementary therapy procedures to improve cell susceptibility of cells to sonodynamic therapy are disclosed.

An intravascular imaging device (102) is provided. In some embodiments, the intravascular imaging device includes a flexible elongate member sized and shaped for insertion into a vessel of a patient, the flexible elongate member having a proximal portion and a distal portion; and an imaging assembly (110) disposed at the distal portion of the flexible elongate member, the imaging assembly including a flex circuit (214) positioned directly around the flexible elongate member. In some embodiments, a method of assembling an intravascular imaging device includes obtaining a flex circuit including a first layer having a plurality of transducers and a second layer having an acoustic backing material; and positioning the flex circuit directly around a distal portion of a flexible elongate member.

Methods and devices for imaging wells using phased array ultrasound imaging devices is described. The devices enable high resolution real-time imaging of a well during various operations in the well, including during completions, fracturing, milling, fishing and drilling operations. The phased array ultrasound imaging devices may be integrated with other well tools, such as a bottom hole assembly (BHA), fishing tools, milling tools, fracturing tools, and drilling tools, in order to integrate imaging capabilities into such tools.

An intraluminal ultrasound imaging device includes a flexible elongate member configured to be positioned within a body lumen of a patient. The flexible elongate member includes a proximal portion and a distal portion. The device also includes an ultrasound imaging assembly disposed at the distal portion of the flexible elongate member. The ultrasound imaging assembly is configured to obtain imaging data of the body lumen. The ultrasound imaging assembly includes a transducer array including a substrate, a silicon oxide layer disposed over the substrate, and a plurality of rows of micromachined ultrasound transducer elements disposed on the silicon oxide layer. Two of the plurality of rows of micromachined ultrasound transducer elements are spaced apart by a trench formed by etching through a screen formed in the silicon oxide layer. Associated devices, systems, and methods are also provided.

An hourglass transducer including a longitudinal driver, a shell, and a pair of endcaps is provided. The driver drives the transducer. The pair of endcaps is attached to ends of the driver and cap the shell enclosing the transducer. The shell includes a first shell end, a second shell end, and a pleated geometry. The first shell end and second shell end are structured with circular cross sections. The pleated geometry is between the first shell end and the second shell end. A perimeter of the pleated geometry is the same as perimeters of the circular cross sections of the first shell end and the second shell end.

An ultrasound endoscope includes: a plurality of piezoelectric elements that are arranged to form a cylinder such that respective longitudinal directions of the piezoelectric elements are aligned, each piezoelectric element being configured to transmit and receive an ultrasound wave; an acoustic lens that is located on outer peripheries of the piezoelectric elements, the acoustic lens being configured to converge ultrasound waves generated by the piezoelectric elements on an outside of the acoustic lens, and transmit ultrasound waves input from the outside of the acoustic lens to the piezoelectric elements; a housing configured to hold distal end sides and proximal end sides of both of the piezoelectric elements and the acoustic lens; and a flexible material that is located between either a distal end or a proximal end of the acoustic lens and the housing, and that has a lower elastic modulus than the acoustic lens.

An ultrasound medical device and an ultrasound diagnostic imaging device are provided that allow orally-fed fluid food, etc. to pass through the esophagus of the subject. The ultrasound medical device includes a capsule-type main body configured to incorporate ultrasound transducers, so that the ultrasound transducers in the capsule-type main body, which has been inserted in a tubular body part of a subject, send ultrasound waves to the subject's interiors and receive reflected waves. The ultrasound medical device further includes a support configured to be incorporated in the capsule-type main body and to have a form of tube with a through-hole axially passing through the tube. The ultrasound transducers are arranged external to the tube.

A method for generating a mechanical wave, including generating a high amplitude mechanical pulse; coupling the mechanical pulse in a proximal end of a transmission member; propagating the mechanical pulse into the transmission member from the proximal end and a distal end thereof; and transmitting the mechanical pulse at the distal end.