The invention relates to mixing elements with a reduced structural depth for static mixers, to static mixers comprising at least two mixing elements with a reduced structural depth, and to a method for mixing fluids using a mixing element with a reduced structural depth or a static mixer comprising at least two mixing elements with a reduced structural depth. In the mixing elements, the thickness of the transverse strut at its thickest point is maximally 0.9 to 1.1 times the thickness of the webs multiplied by the cosine of half the opening angle O divided by the sine of the whole opening angle O.

A static mixer for use with biopharmaceutical compositions includes a shell and a core. The shell defines a flow channel therethrough. The shell is formed as a lattice structure that defines a plurality of voids in fluid communication with the flow channel. The core is disposed within the flow channel of the shell. The core is configured to mix a first fluid and a second fluid together as the first fluid and the second fluid flow through the flow channel. The first fluid or the second fluid is a biopharmaceutical composition.