The present invention relates to a novel chromatography media, more closely a novel IMAC (Immobilized Metal Affinity Chromatography) media. The novel chromatography media comprises a pentaligand and provides high dynamic binding capacity as well as high purity of the sample proteins purified on the media of the invention.

A porous polymer monolith comprises a polymer body having macroporous through-pores that facilitate fluid flow through the body and an array of mesopores adapted to bind from the fluid flow molecules of a predetermined range of sizes, wherein the surface area of the monolith is predominantly provided by the mesopores. Also disclosed is a method of making a porous polymer monolith. The method includes forming a polymer body by phase separation out of a solution containing at least a monomer, a crosslinker and a primary porogen, whereby the body contains multiple macroporous through-pores, wherein the solution further contains a secondary porogen comprising oligomers inert with respect to the monomer and cross-linker but chemically compatible with the monomer so as to form mesostructures within the polymer body during said phase separation, and washing the mesostructures from the body to provide an array of mesopores such that the surface area of the monolith is predominantly provided by the mesopores.

To provide an aldehyde scavenger and a method for removing aldehydes by using the same, for quickly and continuously capturing aldehydes. An aldehyde scavenger comprising at least one O-substituted hydroxylamine or at least one chemically acceptable salt thereof, is used against an aldehyde generation source.

Polymeric sorbents for aldehydes including formaldehyde and acetaldehyde are provided. More particularly, the polymeric sorbents are sulfonic acid-containing polymeric materials with impregnated urea-based compounds. Additionally, methods of making the polymeric sorbent, methods of sorbing aldehydes (i.e., aldehydes that are volatile under use conditions) on the polymeric sorbents, compositions resulting from the sorption of aldehydes on the polymeric sorbents, and filters containing the polymeric sorbents are provided.

The invention relates to a novel biomimetic affinity purification material and its application in the purification of chitosanase, which belongs to the field of industrial biotechnology. The affinity ligand for the biomimetic affinity material is chitodisaccharides, the connecting arm is cyanuric chloride, and the base medium is epoxy-activated Sepharose™ 6B. The desorption constant (Kd) and the theoretical maximum adsorption capacity (Qmax) of the biomimetic affinity material are 24.2 μg/mL and 24.1 mg/g, respectively. Using the above biomimetic affinity material, a chitosanase biomimetic affinity purification method is established, which can produce high-purity chitosanase with high efficiency and low cost, and has good industrial application potential.

A sorbent suitable for sorbing aldehydes includes acidified zeolite impregnated with a urea-based compound, the acidified zeolite having a pore opening of 5 Å or greater and a molar ratio of silicate to aluminate of at least 1.1:1. The sorbent may be prepared by impregnating acidified zeolite with a solution of a urea-based compound, where the acidified zeolite includes proton counterions. The sorbent may be supported on a filter support to provide an air filter.

Methods of producing and isolating .sup.68Ga, .sup.89Zr, .sup.64Cu, .sup.63Zn, .sup.86Y, .sup.61Cu, .sup.99mTc, .sup.45Ti, .sup.13N, .sup.52Mn, or .sup.44Sc and solution targets for use in the methods are disclosed. The methods of producing .sup.68Ga, .sup.89Zr, .sup.64Cu, .sup.63Zn, .sup.86Y, .sup.61Cu, .sup.99mTc, .sup.45Ti, .sup.13N, .sup.52Mn, or .sup.44Sc include irradiating a closed target system with a proton beam. The system can include a solution target. The methods of producing isolated .sup.68Ga, .sup.89Zr, .sup.64Cu, .sup.63Zn, .sup.86Y, .sup.61Cu, .sup.99mTc, .sup.45Ti, .sup.52Mn, or .sup.44Sc further include isolating .sup.68Ga, .sup.89Zr, .sup.64Cu, .sup.63Zn, .sup.86Y, .sup.61Cu, .sup.99mTc, .sup.45Ti, .sup.52Mn, or .sup.44Sc by ion exchange chromatography. An example target includes a target body including a target cavity for receiving the target material; a housing defining a passageway for directing a particle beam at the target cavity; a target window for covering an opening of the target cavity; and a coolant gas flow path disposed in the passageway upstream of the target window.

An object of the present invention is to provide an adsorbent, a filter medium, and an air filter that have good aldehyde removal performance that undergoes little deterioration over time, where the adsorbent is one in which an inorganic porous medium supports at least an amine-based compound and a compound having a sulfide group as a functional group.

Siloxane compounds are removed from the atmospheres by silica supporting an organic sulfonic acid compound. The silica with the organic sulfonic acid compound has a specific surface area down to 500 m.sup.2/g and up to 750 m.sup.2/g and a pore volume down to 0.8 m.sup.3/g and up to 1.2 m.sup.3/g, both measured by nitrogen gas adsorption method and has a pore diameter down to 4 nm and up to 8 nm, at the peak of differential pore volume measured by nitrogen gas adsorption method. The durability of gas sensing element against siloxanes is improved.

This invention relates to a hybrid ligand, a hybrid biomimetic chromedia and a preparing method and a use thereof, wherein the hybrid biomimetic chromedia takes hydrophilic porous microsphere as a substrate in chromatography, activated with allyl bromide and undergoing bromo-alcoholization with N-bromosuccinimide, then coupled with the hybrid ligands. The sequence of the hybrid ligand is phenylalanine-tyrosine-glutamine-5-aminobenzimidazole. The hybrid biomimetic chromedia has both of the two functional groups of phenylalanine-tyrosine-glutamine tripeptide and aminobenzimidazole, while maintaining the high antibody selectivity of polypeptide ligand, hydrophobic electric charge inductive ligand is introduced to achieve more moderate elution requirement, realizing effective antibody separation.