A plate-like chemically strengthened glass having a compression stress layer on the surface of the glass, wherein the compressive stress value (CS.sub.0) at the glass surface of is 500 MPa or more, the plate thickness (t) is 400 .Math.m or more, the compressive stress depth of layer (DOL) is (t × 0.15) .Math.m or more, the compressive stress values (CS.sub.1) and (CS.sub.2) when the depth from the glass surface is ¼ and ½, respectively, are 50 MPa or more, m.sub.1 expressed by {m.sub.1 = (CS.sub.1 - CS.sub.2/(DOL/4 - DOL/2)} is -1.5 MPa/.Math.m or more, m.sub.2 expressed by {m.sub.2 = (CS.sub.2/(DOL/2 - DOL)} is 0 MPa/.Math.m or less, and m.sub.2 is less than m.sub.1.

A plate-like chemically strengthened glass having a compression stress layer on the surface of the glass, wherein the compressive stress value (CS.sub.0) at the glass surface of is 500 MPa or more, the plate thickness (t) is 400 .Math.m or more, the compressive stress depth of layer (DOL) is (t × 0.15) .Math.m or more, the compressive stress values (CS.sub.1) and (CS.sub.2) when the depth from the glass surface is ¼ and ½, respectively, are 50 MPa or more, m.sub.1 expressed by {m.sub.1 = (CS.sub.1 - CS.sub.2/(DOL/4 - DOL/2)} is -1.5 MPa/.Math.m or more, m.sub.2 expressed by {m.sub.2 = (CS.sub.2/(DOL/2 - DOL)} is 0 MPa/.Math.m or less, and m.sub.2 is less than m.sub.1.

A glass vial includes a base including a boron-containing multicomponent glass and a vial opening and holds a liquid active pharmaceutical ingredient formulation. The glass vial has a total volume of <4.5 mL. A filling level of the glass vial with the active pharmaceutical ingredient formulation is not more than 0.25 and a concentration of boron ions, measured at a measurement site below a plane of a middle of the glass vial using a concentration depth profile at a depth in a range from 10 to 30 nm, has a value, averaged over the measurements of the concentration depth profile, that has an excess increase of not more than 30% compared to a concentration of boron ions measured using a concentration depth profile at a depth in a range from 10 to 30 nm with a measurement site in the plane of the middle of the glass vial.

A glass includes: a plurality of components (in wt.-%) as follows:

TABLE-US-00001 Component Proportion (% by weight) SiO.sub.2 50-80  Al.sub.2O.sub.3 0-10 B.sub.2O.sub.3 0-15 Li.sub.2O 0-20 Na.sub.2O 0-20 K.sub.2O 0-25 BaO 0-10 CaO 0-10 MgO 0-10 ZnO 0-10 La.sub.2O.sub.3 0-20 TiO.sub.2 0-5  Cl 0-3  MnO.sub.2 0.2-5.0  Cr.sub.2O.sub.3 0.05-3.0,.sup. 
a sum of a plurality of proportions of Li.sub.2O, Na.sub.2O and K.sub.2O being in a range of from 5.0 to 30.0 wt.-%, a sum of a plurality of amounts of MnO.sub.2 and Cr.sub.2O.sub.3 being at least 0.3 wt.-%, and a ratio of a plurality of proportions of MnO.sub.2 (in wt.-%) and Cr.sub.2O.sub.3 (in wt.-%) being in a range of from 1.5:1 to 12.5:1.

A glass includes: a plurality of components (in wt.-%) as follows:

TABLE-US-00001 Component Proportion (% by weight) SiO.sub.2 50-80  Al.sub.2O.sub.3 0-10 B.sub.2O.sub.3 0-15 Li.sub.2O 0-20 Na.sub.2O 0-20 K.sub.2O 0-25 BaO 0-10 CaO 0-10 MgO 0-10 ZnO 0-10 La.sub.2O.sub.3 0-20 TiO.sub.2 0-5  Cl 0-3  MnO.sub.2 0.2-5.0  Cr.sub.2O.sub.3 0.05-3.0,.sup. 
a sum of a plurality of proportions of Li.sub.2O, Na.sub.2O and K.sub.2O being in a range of from 5.0 to 30.0 wt.-%, a sum of a plurality of amounts of MnO.sub.2 and Cr.sub.2O.sub.3 being at least 0.3 wt.-%, and a ratio of a plurality of proportions of MnO.sub.2 (in wt.-%) and Cr.sub.2O.sub.3 (in wt.-%) being in a range of from 1.5:1 to 12.5:1.

A chemically temperable borosilicate glass article has a low boron content and a corresponding Na.sub.2O content. The articles have good diffusivities and hydrolytical resistance values. When chemically tempered, the borosilicate glass article exhibits a compressive stress CS >400 MPa and a penetration depth DoL >20 μm. A pharmaceutical primary packaging including the borosilicate glass article is also disclosed.

A chemically temperable borosilicate glass article has a low boron content and a corresponding Na.sub.2O content. The articles have good diffusivities and hydrolytical resistance values. When chemically tempered, the borosilicate glass article exhibits a compressive stress CS >400 MPa and a penetration depth DoL >20 μm. A pharmaceutical primary packaging including the borosilicate glass article is also disclosed.

Disclosed is a joined ceramic body comprising a first ceramic portion comprising a first ceramic, a second ceramic portion comprising a second ceramic, and a joining layer formed between the first ceramic portion and the second ceramic portion. The joining layer has a bond thickness of from 0.5 to 20 um and comprises silicon dioxide having a total impurity content of 20 ppm and less. A method of making the joined ceramic body and a joining material are also disclosed.

Disclosed is a joined ceramic body comprising a first ceramic portion comprising a first ceramic, a second ceramic portion comprising a second ceramic, and a joining layer formed between the first ceramic portion and the second ceramic portion. The joining layer has a bond thickness of from 0.5 to 20 um and comprises silicon dioxide having a total impurity content of 20 ppm and less. A method of making the joined ceramic body and a joining material are also disclosed.

A metallic laminate shaped flow path member has both a surface roughness of a flow path inner surface and corrosion resistance at such a level as to be utilizable as a flow path member for use in a supply line for a corrosive fluid in a semiconductor device manufacturing apparatus. A metallic substrate constituting the metallic laminate shaped flow path member has surface irregularities, the inner surface of the flow path of the metallic laminate shaped flow path member is formed with a glass coating layer in such a manner as to fill at least recessed regions of the surface irregularities of the metallic substrate, and the glass coating layer includes at least one of a layer of a P.sub.2O.sub.5—ZnO—Al.sub.2O.sub.3 based glass, a layer of a Bi.sub.2O.sub.3—ZnO—B.sub.2O.sub.3 based glass, and a layer of an SiO.sub.2—B.sub.2O.sub.3—Na.sub.2O based glass.