Patent classifications
C07B2200/11
Antibody targeting cell surface deposited complement protein C3d and use thereof
An anti-C3d antibody or antibody fragment; method for use thereof to kill cancer cells; and related methods and compositions.
Solid composite stabilizer for perchloroethylene (PCE) and preparation method
The solid composite stabilizer for PCE includes the following components in parts by weight: 10 to 30 parts of a phenol-substituted ion-exchange resin, 50 to 80 parts of a basic anion-exchange resin, and 50 to 100 parts of a desiccating agent. The phenol-substituted ion-exchange resin is chloromethylated macroporous polystyrene-divinylbenzene (PS-DVB) substituted by a phenolic compound; and the basic anion-exchange resin is chloromethylated macroporous PS-DVB substituted by an amine compound. The preparation method includes the following step: thoroughly mixing the phenol-substituted ion-exchange resin, the basic anion-exchange resin, and the desiccating agent in a specified ratio to obtain the solid composite stabilizer for PCE. The solid composite stabilizer for PCE is packaged in a glass fiber bag and placed in PCE for storage and use.
COMPLEX COMPOUND AND METHOD FOR MANUFACTURING THE SAME
[Problem] To provide a complex compound useful as a catalyst for a hydrophosphorylation reaction and a process for producing the same.
[Means to Solve the Problem] A complex compound of the present invention is a complex compound of a resin fine particle represented by the following general formula (1):
##STR00001## wherein, R.sup.1 represents a substituted or unsubstituted hydrocarbon group, R.sup.2 represents a substituted or unsubstituted alkyl group or a substituted or unsubstituted aryl group, R.sup.3 and R.sup.4 each independently represent a hydrogen atom, a substituted or unsubstituted alkyl group or a substituted or unsubstituted aryl group, and based on the total of 100% of the values of n and m, the value of n is within the range of 20 to 100%, the value of m is within the range of 0 to 80%, and * represents bonding with the surface of the resin fine particle and a transition metal.
Arene-immobilized ru(II)TsDPEN complexes: synthesis and applications to the asymetric transfer hydrogenation of ketones
Arene-immobilized Ru(II)TsDPEN Noyori-Ikariya catalysts anchored to silica through the coordinated η6-arene are provided. The catalysts efficiently catalyze many reactions, including the asymmetric transfer hydrogenation of ketones to alcohols.
(+)-3-(2,3-DIFLUOROPHENYL)-3-METHOXYPYRROLIDINE OR PHARMACEUTICALLY ACCEPTABLE SALTS THEREOF, A PROCESS FOR PREPARATION THEREOF AND USES THEREOF
Described is a salt of Formula IIb:
##STR00001##
Materials coated with calixarenes
This invention relates to the direct grafting of a calixarene mostly onto the surface of a material, as well as to a grafting process, and certain calixarene intermediates useful for carrying the grafting process.
Affinity Reagent and Catalyst Discovery Through Fiber-Optic Array Scanning Technology
Devices, systems and methods for affinity reagent and catalyst discovery employing a library on a bead HTS platform, each bead comprising affixed non-natural polymers of a distinct bioactive monomer with sequence pre-defined branching and folding in tertiary structures, and fiber-optic array scanning technology.
(+)-3-(2,3-difluorophenyl)-3-methoxypyrrolidine or pharmaceutically acceptable salts thereof, a process for preparation thereof and uses thereof
The disclosure provides a process for manufacturing thereof a salt of Formula IIb: ##STR00001##
Compositions and methods for improving sample identification in indexed nucleic acid libraries
The present invention is concerned with compositions and methods for improving the rate of correct sample identification in indexed nucleic acid library preparations for multiplex next generation sequencing by blocking the 3′ ends of pooled indexed polynucleotides from multiple samples prior to amplification and sequencing.
RETINOIC ACID RECEPTOR ANTAGONISTS AS CHAPERONE-MEDIATED AUTOPHAGY MODULATORS AND USES THEREOF
Compounds, compositions and methods are provided for selectively activating chaperone-mediated autophagy (CMA), protecting cells from oxidative stress, proteotoxicity and lipotoxicity, and/or antagonizing activity of retinoic acid receptor alpha (RAR) in subjects in need thereof.