Cannabis plant material is extracted with a solvent matrix consisting of one or more organic solvents and optionally water. The cannabis plant material is agitated in the solvent matrix and then removed by filtration or centrifugation. Following extraction, the plant material is separated from the solvent matrix by centrifugation. The resulting extract is clarified by membrane filtration which also removes most of the water and water-soluble impurities. The resulting extract is dewaxed using membrane filtration and/or liquid-liquid extraction. Excess solvent and terpenoids are removed by means of molecular weight cutoff membrane filtration and the resulting cannabinoid solution is decarboxylated catalytically. Seed crystals are added to crystallize the cannabinoids.

The present invention describes a method which outlines a process for conversion of CBD to a Δ.sup.9-tetrahydrocannabinol (Δ.sup.9-THC) compound or derivative thereof involving treating a naturally produced CBD intermediate compound with an organoaluminum-based Lewis acid catalyst, under conditions effective to produce the Δ.sup.9-tetrahydrocannabinol compound or derivative thereof at a relatively high concentration. The source of the CBD is from industrial hemp having less than 0.3% Δ.sup.9-THC and extracting and purifying a CBD distillate or isolate or a combination thereof. This procedure will produce Δ.sup.9-THC that is essentially free from any other cannabinoids other than some trace amounts of the initial CBD starting material, or about 95% Δ.sup.9-THC and 2-4% CBD. Another aspect of the present invention relates to a process for further purification and enrichment of the Δ.sup.9-THC using distillation and collecting an essentially pure fraction of Δ.sup.9-THC using additional distillation or enrichment form of purification. Included are methods and processes to scale the reaction from the lab to large scale manufacturing. Included are methods for adding a molecule marker to authenticate high purity Δ.sup.9-THC products. Formulations and uses for pharmaceuticals, nutraceuticals, food products, and topicals are also provided.

The present invention describes a method which outlines a process for conversion of CBD to a Δ.sup.9-tetrahydrocannabinol (Δ.sup.9-THC) compound or derivative thereof involving treating a naturally produced CBD intermediate compound with an organoaluminum-based Lewis acid catalyst, under conditions effective to produce the Δ.sup.9-tetrahydrocannabinol compound or derivative thereof at a relatively high concentration. The source of the CBD is from industrial hemp having less than 0.3% Δ.sup.9-THC and extracting and purifying a CBD distillate or isolate or a combination thereof. This procedure will produce Δ.sup.9-THC that is essentially free from any other cannabinoids other than some trace amounts of the initial CBD starting material, or about 95% Δ.sup.9-THC and 2-4% CBD. Another aspect of the present invention relates to a process for further purification and enrichment of the Δ.sup.9-THC using distillation and collecting an essentially pure fraction of Δ.sup.9-THC using additional distillation or enrichment form of purification. Included are methods and processes to scale the reaction from the lab to large scale manufacturing. Included are methods for adding a molecule marker to authenticate high purity Δ.sup.9-THC products. Formulations and uses for pharmaceuticals, nutraceuticals, food products, and topicals are also provided.

Problem The present invention is to provide a generation method that can generate 3,5-dihydroxy-4-methoxybenzyl alcohol, which was not found at all from raw oyster meat originally, at an extraction phase of oyster meat essence. Solution The present invention heats raw oyster meat from which 3,5-dihydroxy-4-methoxybenzyl alcohol is not detected in a raw state at 98° C. to 100° C. for six hours or more to generate 3,5-dihydroxy-4-methoxybenyl alcohol from oyster meat liquid on which the heating process has been performed.

The invention discloses a method for producing bio-fuel (BF) from a high-viscosity biomass using thermo-chemical conversion of the biomass in a production line (10) with pumping means (PM), heating means (HM) and cooling means (CM). The method has the steps of 1) operating the pumping means, the heating means and the cooling means so that the production line is under supercritical fluid conditions (SCF) to induce biomass conversion in a conversion zone (CZ) within the production line, and 2) operating the pumping means so that at least part of the production line is in an oscillatory flow (OF) mode. The invention is advantageous for providing an improved method for producing biofuel from a high-viscosity biomass. This is performed by an advantageous combination of two operating modes: supercritical fluid (SCF) conditions and oscillatory flow (OF).

Methods of isolating phenols from phenol-containing media. The methods include combining a phospholipid-containing composition with the phenol-containing medium to generate a combined medium, incubating the combined medium to precipitate phenols in the combined medium and thereby form a phenol precipitate phase and a phenol-depleted phase, and separating the phenol precipitate phase and the phenol-depleted phase. The methods can further include extracting phenols from the separated phenol precipitate phase. The extracting can include mixing the separated phenol precipitate phase with an extraction solvent to solubilize in the extraction solvent at least a portion of the phenols originally present in the phenol precipitate phase.

Methods of isolating phenols from phenol-containing media. The methods include combining a phospholipid-containing composition with the phenol-containing medium to generate a combined medium, incubating the combined medium to precipitate phenols in the combined medium and thereby form a phenol precipitate phase and a phenol-depleted phase, and separating the phenol precipitate phase and the phenol-depleted phase. The methods can further include extracting phenols from the separated phenol precipitate phase. The extracting can include mixing the separated phenol precipitate phase with an extraction solvent to solubilize in the extraction solvent at least a portion of the phenols originally present in the phenol precipitate phase.

The present disclosure provides a method preparing Silver-nanocurcumin material for inhibiting new coronavirus. The turmeric powder is heated and stirred and then mixed with silver nitrate solution. After multiple steps of cooling, stirring for reaction and centrifuging and other steps, crude extract of Silver-nanocurcumin is obtained. Then, after further processes such as the multiple washing and centrifuging, a purified composition of Silver-nanocurcumin is obtained. The composition of Silver-nanocurcumin can be used to inhibit the new coronavirus and its similar viruses, and as a source of drugs for the prevention and treatment of diseases derived from the new coronavirus COVID-19 in the future.

In alternative embodiments, provided are industrial processes and methods for extracting or removing cannabinoids, flavonoids and terpenes from plant materials such as trichomes. In alternative embodiments, the cannabinoids, flavonoids and terpenes are extracted or removed from the plant materials using a non-polar, organic solvent, or a mixture of non-polar, organic solvent and polar, organic solvent.

In alternative embodiments, provided are industrial processes and methods for extracting or removing cannabinoids, flavonoids and terpenes from plant materials such as trichomes. In alternative embodiments, the cannabinoids, flavonoids and terpenes are extracted or removed from the plant materials using a non-polar, organic solvent, or a mixture of non-polar, organic solvent and polar, organic solvent.