Patent classifications
C07C51/02
Magnesium lactate fermentation process
A fermentation process for producing magnesium lactate from a carbon source including the steps of: providing a fermentation medium including a fermentable carbon source in a fermentation reactor; fermenting the fermentation medium by a lactic acid producing microorganism in the presence of an alkaline magnesium salt to provide a fermentation broth including magnesium lactate; and recovering solid magnesium lactate from the magnesium lactate containing fermentation broth, wherein during at least 40% of the operating time of the fermentation process, the concentration of solid magnesium lactate in the fermentation broth is maintained in the range of 5-40 vol. %, calculated as solid magnesium lactate crystals on the total of the fermentation broth. The process allows stable operation at high productivity, in combination with efficient product separation.
Method of producing a 2-((meth)allyloxymethyl)acrylic acid derivative, and 2-((meth)allyloxymethyl)acrylic acid alkali metal salt powder
Provided is a method of producing various 2-((meth)allyloxymethyl)acrylic acid derivatives in high yields with no need to load a raw material in a large excess for improving a reaction conversion ratio, and without use of a catalyst having high toxicity or a strong acid catalyst. Also provided are powder compounds that may be utilized as raw materials for synthesizing various chemical products. A method of producing a 2-((meth)allyloxymethyl)acrylic acid derivative includes causing the powder of a salt of a 2-((meth)allyloxymethyl)acrylic acid anion and an alkali metal cation (component A), and a halide (component B) to react with each other to produce a 2-((meth)allyloxymethyl)acrylic acid derivative. The 2-((meth)allyloxymethyl)acrylic acid alkali metal salt powder is the powder of a salt of a 2-((meth)allyloxymethyl)acrylic acid anion and an alkali metal cation, and has a bulk density of 0.50 g/mL or more, or a water content of 0.05 wt % or less.
Method of producing a 2-((meth)allyloxymethyl)acrylic acid derivative, and 2-((meth)allyloxymethyl)acrylic acid alkali metal salt powder
Provided is a method of producing various 2-((meth)allyloxymethyl)acrylic acid derivatives in high yields with no need to load a raw material in a large excess for improving a reaction conversion ratio, and without use of a catalyst having high toxicity or a strong acid catalyst. Also provided are powder compounds that may be utilized as raw materials for synthesizing various chemical products. A method of producing a 2-((meth)allyloxymethyl)acrylic acid derivative includes causing the powder of a salt of a 2-((meth)allyloxymethyl)acrylic acid anion and an alkali metal cation (component A), and a halide (component B) to react with each other to produce a 2-((meth)allyloxymethyl)acrylic acid derivative. The 2-((meth)allyloxymethyl)acrylic acid alkali metal salt powder is the powder of a salt of a 2-((meth)allyloxymethyl)acrylic acid anion and an alkali metal cation, and has a bulk density of 0.50 g/mL or more, or a water content of 0.05 wt % or less.
Method of producing a 2-((meth)allyloxymethyl)acrylic acid derivative, and 2-((meth)allyloxymethyl)acrylic acid alkali metal salt powder
Provided is a method of producing various 2-((meth)allyloxymethyl)acrylic acid derivatives in high yields with no need to load a raw material in a large excess for improving a reaction conversion ratio, and without use of a catalyst having high toxicity or a strong acid catalyst. Also provided are powder compounds that may be utilized as raw materials for synthesizing various chemical products. A method of producing a 2-((meth)allyloxymethyl)acrylic acid derivative includes causing the powder of a salt of a 2-((meth)allyloxymethyl)acrylic acid anion and an alkali metal cation (component A), and a halide (component B) to react with each other to produce a 2-((meth)allyloxymethyl)acrylic acid derivative. The 2-((meth)allyloxymethyl)acrylic acid alkali metal salt powder is the powder of a salt of a 2-((meth)allyloxymethyl)acrylic acid anion and an alkali metal cation, and has a bulk density of 0.50 g/mL or more, or a water content of 0.05 wt % or less.
Water-based extraction and purification processes for cannabinoid acids
The present invention relates to methods of extracting cannabinoid acids from cannabis plant material by combining the plant material with an aqueous solution having a high pH to solubilize cannabinoid acid anions, followed by precipitation of the cannabinoid acids at low pH and filtration. The method provides yields of up to 97%, while high pH purification of ethanol extracted oils yielded purities up to 86%.
Water-based extraction and purification processes for cannabinoid acids
The present invention relates to methods of extracting cannabinoid acids from cannabis plant material by combining the plant material with an aqueous solution having a high pH to solubilize cannabinoid acid anions, followed by precipitation of the cannabinoid acids at low pH and filtration. The method provides yields of up to 97%, while high pH purification of ethanol extracted oils yielded purities up to 86%.
METHOD OF MANUFACTURING FOR TEREPHTHALIC ACID USING POLYETHYLENE TEREPHTHALATE WITH HIGH DEGREE OF POLYMERIZATION MORE THAN 0.75 DL/G OF INTRINSIC VISCOSITY
The present invention relates to a method for production of terephthalic acid using high polymerization degree polyethylene terephthalate, which includes: (i) introducing high polymerization degree polyethylene terephthalate having an intrinsic viscosity of 0.75 dl/g or more into a continuous reactor, and then heating and pressurizing the same to prepare a fluidal polyethylene terephthalate; (ii) introducing a mixed slurry prepared by mixing an alkaline material containing an alkali-metal, a weak acid salt of the alkali-metal and ethylene glycol together into an internal position of the continuous reactor, through which the fluidal polyethylene terephthalate passes, and implementing neat reaction of the fluidal polyethylene terephthalate with the mixed slurry in the continuous reactor to prepare alkali-metal terephthalate; and (iii) dissolving the prepared alkali-metal terephthalate in water, removing foreign substances through filtration and centrifugation, adding acid to the alkali-metal terephthalate dissolved in water and reacting the same, thereby producing terephthalic acid.
METHOD OF MANUFACTURING FOR TEREPHTHALIC ACID USING POLYETHYLENE TEREPHTHALATE WITH HIGH DEGREE OF POLYMERIZATION MORE THAN 0.75 DL/G OF INTRINSIC VISCOSITY
The present invention relates to a method for production of terephthalic acid using high polymerization degree polyethylene terephthalate, which includes: (i) introducing high polymerization degree polyethylene terephthalate having an intrinsic viscosity of 0.75 dl/g or more into a continuous reactor, and then heating and pressurizing the same to prepare a fluidal polyethylene terephthalate; (ii) introducing a mixed slurry prepared by mixing an alkaline material containing an alkali-metal, a weak acid salt of the alkali-metal and ethylene glycol together into an internal position of the continuous reactor, through which the fluidal polyethylene terephthalate passes, and implementing neat reaction of the fluidal polyethylene terephthalate with the mixed slurry in the continuous reactor to prepare alkali-metal terephthalate; and (iii) dissolving the prepared alkali-metal terephthalate in water, removing foreign substances through filtration and centrifugation, adding acid to the alkali-metal terephthalate dissolved in water and reacting the same, thereby producing terephthalic acid.
METHOD OF PREPARING OXALIC ACID
The present invention provides a method of preparing oxalic acid (H.sub.2C.sub.2O.sub.4), the method at least comprising the steps of: (a) providing a metal formate (HCO.sub.2M) containing stream, wherein the metal (M) of the metal formate (HCO.sub.2M) is a monovalent metal selected from the group consisting of Li, Na, K, Cs, Rb and a mixture thereof; (b) heating the metal formate (HCO.sub.2M) containing stream thereby obtaining a metal oxalate (M.sub.2C.sub.2O.sub.4) containing stream; (c) subjecting the metal oxalate (M.sub.2C.sub.2O.sub.4) containing stream to electrodialysis, thereby obtaining at least oxalic acid (M.sub.2C.sub.2O.sub.4) and a metal hydroxide (MOH).
METHOD OF PREPARING OXALIC ACID
The present invention provides a method of preparing oxalic acid (H.sub.2C.sub.2O.sub.4), the method at least comprising the steps of: (a) providing a metal formate (HCO.sub.2M) containing stream, wherein the metal (M) of the metal formate (HCO.sub.2M) is a monovalent metal selected from the group consisting of Li, Na, K, Cs, Rb and a mixture thereof; (b) heating the metal formate (HCO.sub.2M) containing stream thereby obtaining a metal oxalate (M.sub.2C.sub.2O.sub.4) containing stream; (c) subjecting the metal oxalate (M.sub.2C.sub.2O.sub.4) containing stream to electrodialysis, thereby obtaining at least oxalic acid (M.sub.2C.sub.2O.sub.4) and a metal hydroxide (MOH).