C07C209/68

Fluorine-containing complex compound, and production method for fluorine-containing organic compound employing same

An object of the present invention is to enable the synthesis of various fluorine-containing compounds having an organic group at both terminals of their tetrafluoroethylene structure (—CF.sub.2—CF.sub.2—). The present invention provides a fluorine-containing complex compound including a fluorine-containing organic metal compound represented by formula (1a):
R.sup.1—CF.sub.2—CF.sub.2-M.sup.1  (1a)
wherein M.sup.1 is a metal selected from the group consisting of copper, zinc, nickel, iron, cobalt, and tin; and R.sup.1 represents an organic group, and at least one ligand selected from the group consisting of pyridine ring-containing compounds and phosphines.

Fluorine-containing complex compound, and production method for fluorine-containing organic compound employing same

An object of the present invention is to enable the synthesis of various fluorine-containing compounds having an organic group at both terminals of their tetrafluoroethylene structure (—CF.sub.2—CF.sub.2—). The present invention provides a fluorine-containing complex compound including a fluorine-containing organic metal compound represented by formula (1a):
R.sup.1—CF.sub.2—CF.sub.2-M.sup.1  (1a)
wherein M.sup.1 is a metal selected from the group consisting of copper, zinc, nickel, iron, cobalt, and tin; and R.sup.1 represents an organic group, and at least one ligand selected from the group consisting of pyridine ring-containing compounds and phosphines.

Fluorine-containing complex compound, and production method for fluorine-containing organic compound employing same

An object of the present invention is to enable the synthesis of various fluorine-containing compounds having an organic group at both terminals of their tetrafluoroethylene structure (—CF.sub.2—CF.sub.2—). The present invention provides a fluorine-containing complex compound including a fluorine-containing organic metal compound represented by formula (1a):
R.sup.1—CF.sub.2—CF.sub.2-M.sup.1  (1a)
wherein M.sup.1 is a metal selected from the group consisting of copper, zinc, nickel, iron, cobalt, and tin; and R.sup.1 represents an organic group, and at least one ligand selected from the group consisting of pyridine ring-containing compounds and phosphines.

SALTS OF POTASSIUM ATP CHANNEL OPENERS AND USES THEREOF
20220047605 · 2022-02-17 ·

Provided are immediate or prolonged administration of certain salts of K.sub.ATP channel openers such as diazoxide to a subject to achieve novel pharmacodynamic, pharmacokinetic, therapeutic, physiological, metabolic and compositional outcomes in the treatment of diseases or conditions involving K.sub.ATP channels. Also provided are pharmaceutical formulations, methods of administration and dosing of the salts that achieve these outcomes and reduce the incidence of adverse effects in treated individuals. Further provided are method of co-administering the salts with other drugs to treat diseases of humans and animals.

SALTS OF POTASSIUM ATP CHANNEL OPENERS AND USES THEREOF
20220047605 · 2022-02-17 ·

Provided are immediate or prolonged administration of certain salts of K.sub.ATP channel openers such as diazoxide to a subject to achieve novel pharmacodynamic, pharmacokinetic, therapeutic, physiological, metabolic and compositional outcomes in the treatment of diseases or conditions involving K.sub.ATP channels. Also provided are pharmaceutical formulations, methods of administration and dosing of the salts that achieve these outcomes and reduce the incidence of adverse effects in treated individuals. Further provided are method of co-administering the salts with other drugs to treat diseases of humans and animals.

PROCESS FOR PREPARING SUBSTITUTED ANILINES

The present invention relates to a process for preparing compounds of the formula (I)

##STR00001##

starting from compounds of the formula (II)

##STR00002##

wherein R.sup.1, R.sup.2, R.sup.3 and R.sup.3′ are defined in according to the invention.

PROCESS FOR PREPARING SUBSTITUTED ANILINES

The present invention relates to a process for preparing compounds of the formula (I)

##STR00001##

starting from compounds of the formula (II)

##STR00002##

wherein R.sup.1, R.sup.2, R.sup.3 and R.sup.3′ are defined in according to the invention.

Triphenylamine derivative and use therefor

A triphenylamine derivative represented by formula (1) exhibits good solubility in an organic solvent and allows an organic EL element having excellent luminance characteristics to be achieved when formed into a thin film and applied to a positive hole injection layer. ##STR00001##
(In the formula, R.sup.1 to R.sup.17 mutually independently represent a hydrogen atom, a halogen atom, a nitro group, a cyano group, an amino group, an aldehyde group, a hydroxyl group, a thiol group, a carboxylic acid group, and the like; and l, m, and n mutually independently represent an integer 1 to 5.)

Triphenylamine derivative and use therefor

A triphenylamine derivative represented by formula (1) exhibits good solubility in an organic solvent and allows an organic EL element having excellent luminance characteristics to be achieved when formed into a thin film and applied to a positive hole injection layer. ##STR00001##
(In the formula, R.sup.1 to R.sup.17 mutually independently represent a hydrogen atom, a halogen atom, a nitro group, a cyano group, an amino group, an aldehyde group, a hydroxyl group, a thiol group, a carboxylic acid group, and the like; and l, m, and n mutually independently represent an integer 1 to 5.)

SOLID-SUPPORTED PALLADIUM (II) COMPLEX AS A HETEROGENEOUS CATALYST FOR CROSS COUPLING REACTIONS AND METHODS THEREOF

A solid-supported catalyst ligand which chelates palladium (II) species to form a complex that functions as a heterogeneous catalyst that is stable and can be recycled without significantly losing any catalytic activity in a variety of chemical transformations, a method for producing the solid-supported catalyst ligand and a method for catalyzing a palladium cross-coupling reaction, such as the Suzuki-Miyaura, Mizoroki-Heck, and Sonagashira reactions.