Disclosed herein are methods for preparing [(2S,3R)N-[(2S)-3-(cyclopent-1-en-1-yl)-1-[(2R)-2-methyloxiran-2-yl]-1-oxopropan-2-yl]-3-hydroxy-3-(4-methoxyphenyl)-2-[(2S)-2-[2-(morpholin-4-yl)acetamido]propanamido]propanamide (compound G): and precursors thereof.

##STR00001##

Disclosed herein are methods for preparing [(2S,3R)N-[(2S)-3-(cyclopent-1-en-1-yl)-1-[(2R)-2-methyloxiran-2-yl]-1-oxopropan-2-yl]-3-hydroxy-3-(4-methoxyphenyl)-2-[(2S)-2-[2-(morpholin-4-yl)acetamido]propanamido]propanamide (compound G): and precursors thereof.

##STR00001##

A silver impregnation solution containing: (i) silver ions, (ii) a polar organic additive containing two to four carbon atoms and two to four functional groups selected from hydroxy, carboxylic acid, and amine groups, provided that a carboxylic acid group can only be present along with a hydroxy or amine group, and provided that an amine group can only be present along with a hydroxy or carboxylic acid group; and (iii) water; wherein components (i) and (ii) are water soluble and dissolved in the impregnation solution. Also described herein is a method for producing a catalyst effective in the oxidative conversion of ethylene to ethylene oxide, the method comprising subjecting a refractory carrier impregnated with the above-described silver impregnation solution to a calcination process. Also described herein is a method for converting ethylene to ethylene oxide by use of the foregoing silver catalyst, as produced by the above-described silver impregnation solution.

A silver impregnation solution containing: (i) silver ions, (ii) a polar organic additive containing two to four carbon atoms and two to four functional groups selected from hydroxy, carboxylic acid, and amine groups, provided that a carboxylic acid group can only be present along with a hydroxy or amine group, and provided that an amine group can only be present along with a hydroxy or carboxylic acid group; and (iii) water; wherein components (i) and (ii) are water soluble and dissolved in the impregnation solution. Also described herein is a method for producing a catalyst effective in the oxidative conversion of ethylene to ethylene oxide, the method comprising subjecting a refractory carrier impregnated with the above-described silver impregnation solution to a calcination process. Also described herein is a method for converting ethylene to ethylene oxide by use of the foregoing silver catalyst, as produced by the above-described silver impregnation solution.

A composite solid base catalyst, a manufacturing method thereof and a manufacturing method of glycidol are provided. The composite solid base catalyst includes an aluminum carrier and a plurality of calcium particles. The plurality of calcium particles are supported by the aluminum carrier. Beta basic sites of the composite solid base catalyst are 0.58 mmol/g-3.89 mmol/g.

A composite solid base catalyst, a manufacturing method thereof and a manufacturing method of glycidol are provided. The composite solid base catalyst includes an aluminum carrier and a plurality of calcium particles. The plurality of calcium particles are supported by the aluminum carrier. Beta basic sites of the composite solid base catalyst are 0.58 mmol/g-3.89 mmol/g.

Stabilized compositions employing a sequestrant system and a binding system for improving shelf stability and dispensing stability of a solid activated bleach composition are disclosed. The compositions contain a peroxygen source and a catalyst activator which require generation of a peroxycarboxylic acid or other active oxygen sanitizing agent at a point of use. Stabilized compositions employ a sequestrant system including a phosphonic acid and/or dipicolinic acid sequestrant and a binding system comprising an anionic surfactant for a solid formulation of a catalyst activator and peroxygen source to provide shelf stability and dispensing stability for a activated bleach composition. Methods of formulating and use are further disclosed.

Stabilized compositions employing a sequestrant system and a binding system for improving shelf stability and dispensing stability of a solid activated bleach composition are disclosed. The compositions contain a peroxygen source and a catalyst activator which require generation of a peroxycarboxylic acid or other active oxygen sanitizing agent at a point of use. Stabilized compositions employ a sequestrant system including a phosphonic acid and/or dipicolinic acid sequestrant and a binding system comprising an anionic surfactant for a solid formulation of a catalyst activator and peroxygen source to provide shelf stability and dispensing stability for a activated bleach composition. Methods of formulating and use are further disclosed.

The invention relates to a method for obtaining glycidol in a semi-continuous or continuous manner by decarboxylating glycerol carbonate at reduced pressure, at a temperature less than or equal to 130 C. and in the presence of alkoxide catalysts of alkaline metals and alkaline earth metals, metal oxides, mixed metal oxides, metal stannates and mixed metal stannates, all of which optionally supported via SiO.sub.2, -Al.sub.2O.sub.3, MgO and ZrO.sub.2.

The invention relates to a method for obtaining glycidol in a semi-continuous or continuous manner by decarboxylating glycerol carbonate at reduced pressure, at a temperature less than or equal to 130 C. and in the presence of alkoxide catalysts of alkaline metals and alkaline earth metals, metal oxides, mixed metal oxides, metal stannates and mixed metal stannates, all of which optionally supported via SiO.sub.2, -Al.sub.2O.sub.3, MgO and ZrO.sub.2.