The current invention is directed towards compounds of the general formula (I), wherein the integers are defined as follows: R.sup.1 is —(CH.sub.2)nCH(CH.sub.3).sub.2, R.sup.2 is —(CH.sub.2).sub.n+2CH(CH.sub.3).sub.2, G.sup.1 selected from monosaccharides with 4 to 6 carbon atoms, x in the range of from 1.1 to 4, n is a number in the range of from zero to 3. ##STR00001##

Disclosed herein is a class of chiral binuclear metal complexes for stereoselective glycoside hydrolysis of saccharides, and more particular chiral binuclear transition metal complex catalysts that discriminate epimeric glycosides and α- and β-glycosidic bonds of saccharides in aqueous solutions at near physiological pHs. The chiral binuclear metal complexes include a Schiff-base-type ligand derived from a chiral diamino building block, and a binuclear transition metal core, each which can be varied for selectivity. The metal core is a Lewis-acidic metal ion, such as copper, zinc, lanthanum, iron and nickel. The Schiff-base may be a reduced or non-reduced Schiff-base derived from aliphatic linear, aliphatic cyclic diamino alcohols or aromatic aldehydes. The ligand can be a penta- or heptadentate ligand derived from pyridinecarbaldehydes, benzaldehydes, linear or cyclic diamines or diamino alcohols.

Disclosed herein is a class of chiral binuclear metal complexes for stereoselective glycoside hydrolysis of saccharides, and more particular chiral binuclear transition metal complex catalysts that discriminate epimeric glycosides and α- and β-glycosidic bonds of saccharides in aqueous solutions at near physiological pHs. The chiral binuclear metal complexes include a Schiff-base-type ligand derived from a chiral diamino building block, and a binuclear transition metal core, each which can be varied for selectivity. The metal core is a Lewis-acidic metal ion, such as copper, zinc, lanthanum, iron and nickel. The Schiff-base may be a reduced or non-reduced Schiff-base derived from aliphatic linear, aliphatic cyclic diamino alcohols or aromatic aldehydes. The ligand can be a penta- or heptadentate ligand derived from pyridinecarbaldehydes, benzaldehydes, linear or cyclic diamines or diamino alcohols.

The method for purifying oses from hemicellulose originating from lignocellulosic biomass includes eliminating the cellulose matrix and the solid residues and/or the suspended materials from the acid hydrolysate containing oses in order to obtain a clarified hydrolysate, and subjecting the clarified hydrolysate, without adding any basic chemical reagent to increase the pH to at least one step of ultrafiltration and/or to at least one step of nanofiltration, so as to obtain a filtrate containing the majority of the pentoses and a retentate containing the species likely to precipitate under the effect of an increase in the pH. The filtrate is treated by at least one step of electrodialysis so as to recover the acid catalyst from an acid-supplemented solution, and obtain a deacidified filtrate.

The present disclosure relates to the methods for the preparation of reactive [F-18]fluoride in a form of [F-18]sulfonyl fluoride suitable for efficient radiolabeling without an azeotropic evaporation step by the use of anion exchange resin and sulfonyl chloride, and its applications in the manufacturing of PET radiopharmaceuticals.

The present disclosure relates to the methods for the preparation of reactive [F-18]fluoride in a form of [F-18]sulfonyl fluoride suitable for efficient radiolabeling without an azeotropic evaporation step by the use of anion exchange resin and sulfonyl chloride, and its applications in the manufacturing of PET radiopharmaceuticals.

The current invention is directed towards mixtures of compounds, comprising (A) in the range of from 93 to 97% by weight compound of general formula (I) (B) in the range of from 3 to 6.5% by weight compound of general formula (II) (C) in the range of from 0.2 to 0.5% by weight compound of general formula (III) wherein the integers are defined as follows: R.sup.1 is —(CH.sub.2).sub.nCH.sub.3, R.sup.2 is —(CH.sub.2).sub.n+2CH.sub.3, R.sup.3 is —(CH.sub.2).sub.n+1CH(CH.sub.3).sub.2, R.sup.4 is —(CH.sub.2).sub.n−1CH(CH.sub.3).sub.2 G.sup.1 selected from monosaccharides with 4 to 6 carbon atoms, x in the range of from 1.1 to 10, n is a number in the range of from 1 to 4. ##STR00001##

A method for separating hydrolysis product of biomass is provided. The method includes providing a mixture solution containing a hydrolysis product of biomass and a divalent metal salt, adjusting the pH value of the mixture solution to between 1-4.6, and performing a filtering procedure on the mixture solution using a nanofiltration membrane to obtain a concentrated solution and a filtrate, wherein the concentrated solution mainly includes the hydrolysis product of biomass and the filtrate mainly includes the divalent metal salt.

A method for separating hydrolysis product of biomass is provided. The method includes providing a mixture solution containing a hydrolysis product of biomass and a divalent metal salt, adjusting the pH value of the mixture solution to between 1-4.6, and performing a filtering procedure on the mixture solution using a nanofiltration membrane to obtain a concentrated solution and a filtrate, wherein the concentrated solution mainly includes the hydrolysis product of biomass and the filtrate mainly includes the divalent metal salt.

In some aspects, the present disclosure relates to a method of hydrolyzing a polysaccharide to obtain the corresponding saccharides using an amino acid solution. In some embodiments, the present disclosure provides a method of using an amino acid salt such as hydrogen glycine in a solution to obtain a monosaccharide such as glucose, xylose, or fructose.