C07K16/02

HYPERIMMUNIZED EGG PRODUCT FOR TREATING OR PREVENTING ALCOHOLIC LIVER DISEASE AND GRAFT-VERSUS-HOST DISEASE
20240199723 · 2024-06-20 · ·

In one aspect, the present disclosure is directed to a method for preventing or treating alcoholic liver disease or graft-versus-host disease in a subject in need thereof, comprising administering to the subject a therapeutically effective amount of a hyperimmunized egg product obtained from an egg-producing animal, thereby preventing or treating the alcoholic liver disease or the graft-versus-host disease in the subject, wherein the hyperimmunized egg product comprises a therapeutically effective amount of one or more antibodies to an antigen selected from the group consisting of Enterococcus faecalis, Enterococcus faecalis cytolysin toxin, and Enterococcus faecium. The present disclosure is also directed to hyperimmunized eggs and egg products produced by an animal that has been hyperimmunized with an antigen selected from the group consisting of Enterococcus faecalis, isolated Enterococcus faecalis cytolysin toxin, and Enterococcus faecium. Methods of preparing the hyperimmunized eggs and egg products are also disclosed.

Compositions and methods for reducing at least one symptom of human allergy to cats

The present application provides compositions, methods, and systems for reducing allergic response to Fel D1. Such compositions, methods, and systems generally include a supplement comprising an anti-Fel D1 molecule and an animal digest.

VACCINES AND IMMUNOGLOBULINS TARGETING AFRICAN SWINE FEVER VIRUS, METHODS OF PREPARING SAME, AND METHODS OF USING SAME
20240181032 · 2024-06-06 ·

The present disclosure provides a method of isolating and preparing live African Swine Fever (ASF) viruses (ASFV) and an ASFV vaccine composed of ASF virus particles. ASF viral components, and/or immunosuppressive protein factors. The ASFV vaccine can be used to immunize pigs and wild boars, or can be used to immunize species other than pig or wild boar, such as fowl, bovine, goat, rabbit, donkey or horse, to generate polyclonal immunoglobulins with broad-spectrum specificity to the ASFV. The ASFV-specific immunoglobulins then can be extracted and purified. The ASFV-specific immunoglobulins can provide acute treatment of ASF-infected pigs or wild boars or preventative treatment for pigs or wild boars at risk of ASF, for example that may have been exposed to ASFV or ASFV-infected subjects.

Antibody against alopecia-inducing substance as antigen, composition and production method
10246520 · 2019-04-02 · ·

Causes of hair loss have not been completely clarified and still remain unknown in many points. However, it appears that hair loss is partly caused by a mechanism wherein androgenic hormones in the scalp become active via the activation of DHT hormone by 5-reductase and thus the activity of cells in hair roots is lost. In the present invention, an antibody, said antibody being obtained by inoculating a female bird with 5-reductase or DHT as an antigen, is administered to the scalp so that the activity of DHT is suppressed and the activity of cells in hair roots is elevated. This antibody can be used in the form of a composition together with other component(s), for example, as a hair tonic together with another hair growth promoter.

Antibody against alopecia-inducing substance as antigen, composition and production method
10246520 · 2019-04-02 · ·

Causes of hair loss have not been completely clarified and still remain unknown in many points. However, it appears that hair loss is partly caused by a mechanism wherein androgenic hormones in the scalp become active via the activation of DHT hormone by 5-reductase and thus the activity of cells in hair roots is lost. In the present invention, an antibody, said antibody being obtained by inoculating a female bird with 5-reductase or DHT as an antigen, is administered to the scalp so that the activity of DHT is suppressed and the activity of cells in hair roots is elevated. This antibody can be used in the form of a composition together with other component(s), for example, as a hair tonic together with another hair growth promoter.

Kit for a Determination Method for Calprotectin and the Use of Calprotectin as a Predictive Marker for Cardiovascular Disease
20190049439 · 2019-02-14 ·

An assay kit for the use in a method for the detection of potential for CVD or propensity to CVD in a human or non-human animal subject. The method including assessing the concentration of calprotectin in a calprotectin-containing sample taken from the subject.

COATED EGG YOLK CORES, METHODS OF MAKING AND METHODS OF USE THEREOF
20190045830 · 2019-02-14 ·

A method of making coated avian egg yolk cores includes providing dried avian egg yolk cores having a diameter of 100 to 1500 micrometers, applying avian egg albumen to the dried avian egg yolk cores to provide the coated avian egg yolk cores, and optionally drying the coated avian egg yolk cores, wherein the ratio of dry avian egg albumen to dried avian egg yolk in the coated avian egg yolk cores is 1:10 to 10:1. Also included are the coated avian egg yolk cores, food and feed additives containing the coated avian egg yolk cores and food and feed compositions containing the coated avian egg yolk cores.

COATED EGG YOLK CORES, METHODS OF MAKING AND METHODS OF USE THEREOF
20190045830 · 2019-02-14 ·

A method of making coated avian egg yolk cores includes providing dried avian egg yolk cores having a diameter of 100 to 1500 micrometers, applying avian egg albumen to the dried avian egg yolk cores to provide the coated avian egg yolk cores, and optionally drying the coated avian egg yolk cores, wherein the ratio of dry avian egg albumen to dried avian egg yolk in the coated avian egg yolk cores is 1:10 to 10:1. Also included are the coated avian egg yolk cores, food and feed additives containing the coated avian egg yolk cores and food and feed compositions containing the coated avian egg yolk cores.

ANTIBODIES AGAINST GLYPICAN-3 AND THEIR USES IN CANCER DIAGNOSIS AND TREATMENT
20190016818 · 2019-01-17 ·

The present invention relates to anti-GPC3 antibodies and their applications. The invention investigates the potential inhibitory effect of anti-GPC3 antibodies on tumor growth, proliferation, migration and their applications for diagnostic and therapeutic purposes.

ANTIBODIES AGAINST GLYPICAN-3 AND THEIR USES IN CANCER DIAGNOSIS AND TREATMENT
20190016818 · 2019-01-17 ·

The present invention relates to anti-GPC3 antibodies and their applications. The invention investigates the potential inhibitory effect of anti-GPC3 antibodies on tumor growth, proliferation, migration and their applications for diagnostic and therapeutic purposes.