A therapeutic article of manufacture that includes a body having fibers treated with a mixture including metal-modified cerium oxide nanoparticles (mCNPs) and one or more of a polymeric binder, a dispersant and a stabilizer. The mCNPs have a predominant 3+ surface charge and in a range of about 3-35 nanometers (nm) in size. The mCNPs are mixed in an amount that is in a range of about 0.01 to 0.1 weight percentage of the mixture having the mCNPs and the one or more of a polymeric binder, a dispersant and a stabilizer. The metal (m) is an antimicrobial promoting metal that is non-ionizing. A method is also provided that promotes wound healing and/or antimicrobial infection control with a barrier of the therapeutic article of manufacture.

A therapeutic article of manufacture that includes a body having fibers treated with a mixture including metal-modified cerium oxide nanoparticles (mCNPs) and one or more of a polymeric binder, a dispersant and a stabilizer. The mCNPs have a predominant 3+ surface charge and in a range of about 3-35 nanometers (nm) in size. The mCNPs are mixed in an amount that is in a range of about 0.01 to 0.1 weight percentage of the mixture having the mCNPs and the one or more of a polymeric binder, a dispersant and a stabilizer. The metal (m) is an antimicrobial promoting metal that is non-ionizing. A method is also provided that promotes wound healing and/or antimicrobial infection control with a barrier of the therapeutic article of manufacture.

A wound healing composition is provided that includes a tissue adhesive or epithelial tissue healing agent and metal-modified cerium oxide nanoparticles (mCNPs). The nCNPs have a predominant 3+ surface charge and are in a range of about 3-35 nanometers (nm) in size and mixed in an amount that is in a range of about 0.01 to 0.1 weight percentage of a mixture having the tissue adhesive or epithelial tissue healing agent and the mCNPs. The metal (m) is a stable metallic metal with antimicrobial properties and non-ionizing. The mCNPs includes AgCNP2. A method is provided that uses the healing composition to treat a wound or epithelial tissue. The composition can be used to treat the skin or eye and/or subcutaneous tissue.

A wound healing composition is provided that includes a tissue adhesive or epithelial tissue healing agent and metal-modified cerium oxide nanoparticles (mCNPs). The nCNPs have a predominant 3+ surface charge and are in a range of about 3-35 nanometers (nm) in size and mixed in an amount that is in a range of about 0.01 to 0.1 weight percentage of a mixture having the tissue adhesive or epithelial tissue healing agent and the mCNPs. The metal (m) is a stable metallic metal with antimicrobial properties and non-ionizing. The mCNPs includes AgCNP2. A method is provided that uses the healing composition to treat a wound or epithelial tissue. The composition can be used to treat the skin or eye and/or subcutaneous tissue.

A configuration in which an upper auxiliary layer of an absorber includes a super absorbent nonwoven fabric having a surface exposed on an uppermost surface of the absorber and having a Klemm water absorptiveness of 100 mm or more, first super absorbent polymer particles adjacent to a back surface of the super absorbent nonwoven fabric. The main absorption layer of the absorber is a cell absorbing sheet including second super absorbent polymer particles contained in the cells arranged at intervals. A convex bulging upward is formed at each cell in an upper sheet. The first super absorbent polymer particles are fixed to the upper surface of the upper sheet. An adhesion amount of the first super absorbent polymer particles on the upper surface of the upper sheet increases from the top of a convex toward the bottom of a valley between a convex and a convex adjacent each other.

A configuration in which an upper auxiliary layer of an absorber includes a super absorbent nonwoven fabric having a surface exposed on an uppermost surface of the absorber and having a Klemm water absorptiveness of 100 mm or more, first super absorbent polymer particles adjacent to a back surface of the super absorbent nonwoven fabric. The main absorption layer of the absorber is a cell absorbing sheet including second super absorbent polymer particles contained in the cells arranged at intervals. A convex bulging upward is formed at each cell in an upper sheet. The first super absorbent polymer particles are fixed to the upper surface of the upper sheet. An adhesion amount of the first super absorbent polymer particles on the upper surface of the upper sheet increases from the top of a convex toward the bottom of a valley between a convex and a convex adjacent each other.

Methods of using fiber-reinforced composite articles useful in supporting or immobilizing an injured body part is disclosed. The composite is a multi-layer, flexible precursor including fiber reinforcement plies, which can be rapidly cured into a rigid body using a thermosetting resin. Methods of making and using the same are also disclosed, along with kits containing such composite articles.

Methods of using fiber-reinforced composite articles useful in supporting or immobilizing an injured body part is disclosed. The composite is a multi-layer, flexible precursor including fiber reinforcement plies, which can be rapidly cured into a rigid body using a thermosetting resin. Methods of making and using the same are also disclosed, along with kits containing such composite articles.

Catheter securement compositions and methods providing significantly strong securement, water resistant seal, effective hemostasis, and antibacterial properties at and around vascular access sites. By securing the insertion site and the hub to the skin, the composition and method reduce complications such as catheter dislodgement, catheter infiltration, catheter migration, catheter occlusion, catheter-related phlebitis, and catheter-related infections.

Catheter securement compositions and methods providing significantly strong securement, water resistant seal, effective hemostasis, and antibacterial properties at and around vascular access sites. By securing the insertion site and the hub to the skin, the composition and method reduce complications such as catheter dislodgement, catheter infiltration, catheter migration, catheter occlusion, catheter-related phlebitis, and catheter-related infections.