The present invention provides a composition comprising fetal cartilage tissue-derived cells and a fetal cartilage tissue-derived extracellular matrix as active ingredients for regenerating a growth plate. The composition for regenerating a growth plate can inhibit bone bridge formation in a growth plate injury region without a scaffold and differentiate to a growth plate cartilage tissue to effectively fill and regenerate the injured region therewith, whereby the regenerated growth plate tissue can recover growth ability. In addition, the composition is compatible with and safe to biological tissues and is characterized by high reproducibility and homogeneity.

The present invention provides a composition comprising fetal cartilage tissue-derived cells and a fetal cartilage tissue-derived extracellular matrix as active ingredients for regenerating a growth plate. The composition for regenerating a growth plate can inhibit bone bridge formation in a growth plate injury region without a scaffold and differentiate to a growth plate cartilage tissue to effectively fill and regenerate the injured region therewith, whereby the regenerated growth plate tissue can recover growth ability. In addition, the composition is compatible with and safe to biological tissues and is characterized by high reproducibility and homogeneity.

Disclosed is a method of crosslinking hair or other keratin fibers by (i) providing a crosslinking agent comprising an oxidized sugar having at least two aldehyde groups; and (ii) infiltrating a plurality of non-crosslinked hair or other keratin fibers with the crosslinking agent under conditions effective to cause protein molecules contained in the non-crosslinked hair or other keratin fibers to become crosslinked, thereby yielding a population of crosslinked hair or other keratin fibers. The protein molecules include amine groups that react with the aldehyde groups of the oxidized sugar to yield the crosslinked hair or other keratin fibers. Also disclosed are formulations for crosslinking hair or other keratin fibers and methods of using the formulations to treat human hair to maintain a desired three dimensional structure. This formulation includes a crosslinking agent having a plurality of oxidized sugars having at least two aldehyde groups or mixture thereof.

A method for producing a part in the form of a solid block from a natural material in particulate form containing scleroproteins. A phase of heating the natural material, under compression at a pressure greater than or equal to 30 MPa, to a temperature greater than or equal to the denaturation temperature of the scleroproteins contained in the material. A phase of cooling the material thus obtained to a temperature less than 100° C., while maintaining the compression during at least a part of the cooling phase.

A method for producing a part in the form of a solid block from a natural material in particulate form containing scleroproteins. A phase of heating the natural material, under compression at a pressure greater than or equal to 30 MPa, to a temperature greater than or equal to the denaturation temperature of the scleroproteins contained in the material. A phase of cooling the material thus obtained to a temperature less than 100° C., while maintaining the compression during at least a part of the cooling phase.

A natural binder for binding biomasses and industrial waste and/or recycled materials, using processes employed for petroleum-derived binders, includes a mixture of a protein flour, a plant hydrolyzate, and a magnesium oxide.

A natural binder for binding biomasses and industrial waste and/or recycled materials, using processes employed for petroleum-derived binders, includes a mixture of a protein flour, a plant hydrolyzate, and a magnesium oxide.

The present invention relates to a medical implant for cartilage and/or bone repair at an articulating surface of a joint. The implant comprises a contoured implant body and at least one extending post. The implant body has an articulating surface configured to face the articulating part of the joint and a bone contact surface configured to face the bone structure of a joint, where the said articulating and bone contact surfaces face mutually opposite directions and said bone contact surface is provided with the extending post. A cartilage contact surface connects the articulating and the bone contact surfaces and is configured to contact the cartilage surrounding the implant body in a joint. The articulating surface has a layer that consists of titanium nitride (TiN) as the wear-resistant material. The cartilage contact surface has a coating that substantially consists of a material having chondrointegration properties.

The present invention relates to a medical implant for cartilage and/or bone repair at an articulating surface of a joint. The implant comprises a contoured implant body and at least one extending post. The implant body has an articulating surface configured to face the articulating part of the joint and a bone contact surface configured to face the bone structure of a joint, where the said articulating and bone contact surfaces face mutually opposite directions and said bone contact surface is provided with the extending post. A cartilage contact surface connects the articulating and the bone contact surfaces and is configured to contact the cartilage surrounding the implant body in a joint. The articulating surface has a layer that consists of titanium nitride (TiN) as the wear-resistant material. The cartilage contact surface has a coating that substantially consists of a material having chondrointegration properties.

A turkey collagen hydrolysate composition is prepared from turkey collagen sources, wherein the composition has: a protein concentration of from about 80 wt % to 100 wt %; a protein molecular weight distribution wherein from about 80% to 100% of the protein in the turkey collagen hydrolysate composition has a molecular weight of from about 500 to about 15,000 Daltons; a protein solubility of from about 97% to 100% at a pH selected from the group consisting of pH 7.0, pH 3.4, pH 5, and all of pH 7.0, pH 5, and pH 3.4; and a protein amino acid content of 3 to 25 glycine (g/100 g sample), 0.5 to 15 hydroxyproline (g/100 g sample), 1 to 18 proline (g/100 g sample), 0.02 to 4 taurine (g/100 g sample), and 0.05 to 3 tryptophan (g/100 g sample). Methods of preparing turkey collagen hydrolysate compositions are described.