The present disclosure relates to a method for obtaining a high molecular weight chitosan with a lower acetylation degree and its use in human or veterinarian medicine. More specifically, to the obtaining of this biomaterial by means of a simpler process, with reduced energy costs, when compared with conventional procedures.

Hydrogels comprising a macromolecular matrix and water may be used to augment soft tissue of a human being, promote or support cell or tissue viability or proliferation, create space in tissue, and for other purposes. A macromolecular matrix may comprise a hyaluronic acid component crosslinked to a silk fibroin component.

Hydrogels comprising a macromolecular matrix and water may be used to augment soft tissue of a human being, promote or support cell or tissue viability or proliferation, create space in tissue, and for other purposes. A macromolecular matrix may comprise a hyaluronic acid component crosslinked to a silk fibroin component.

The disclosed embodiments include a blend of bison fibers, another fiber, and adhesives. The bison fibers are sheared from a bison, scoured, dehaired, blended with various other fibers and/or compositions, carded, and manufactured into insulation. The bison hairs can be categorized by diameter into one of four categories: prime, drop A, drop B, or drop C. Furthermore, bison fiber can be categorized based on length, coarseness, weight, and/or where on the bison it was sheared from. The insulation can be batted, woven, knit, loose, and/or other similar types. The insulation can be used for garments, outdoor equipment, bedding products, and/or other products. The weight of the insulation can be between 40 grams per square meter and 500 grams per square meter. The bison fiber can be blended with recycled polyester, bison fiber, wool, bast fiber, cellulose fiber, and/or synthetic fiber. The adhesives can be low-melt poly, or resin.

The disclosed embodiments include a blend of bison fibers, another fiber, and adhesives. The bison fibers are sheared from a bison, scoured, dehaired, blended with various other fibers and/or compositions, carded, and manufactured into insulation. The bison hairs can be categorized by diameter into one of four categories: prime, drop A, drop B, or drop C. Furthermore, bison fiber can be categorized based on length, coarseness, weight, and/or where on the bison it was sheared from. The insulation can be batted, woven, knit, loose, and/or other similar types. The insulation can be used for garments, outdoor equipment, bedding products, and/or other products. The weight of the insulation can be between 40 grams per square meter and 500 grams per square meter. The bison fiber can be blended with recycled polyester, bison fiber, wool, bast fiber, cellulose fiber, and/or synthetic fiber. The adhesives can be low-melt poly, or resin.

An aqueous adhesive composition and a process for preparing such compositions are disclosed. The composition comprises macromolecular complex comprising (A) a first component comprising (i) a framework element and (ii) a polyphenol, and (B) second component comprising a polypeptide, oligopeptide, amino acid, or polyamine. The framework element comprises (a) a polypeptide, oligopeptide, amino acid, or polyamine, (b) a polysaccharide, oligosaccharide, or monosaccharide, or a saccharide conjugate, or (c) a lignin, a lignan or a lignin conjugate. The polyphenol comprises a tannin, a tannic acid, a flavonoid, or a poly-resorcinol. An adhesive precursor composition comprising the first component is also disclosed.

An aqueous adhesive composition and a process for preparing such compositions are disclosed. The composition comprises macromolecular complex comprising (A) a first component comprising (i) a framework element and (ii) a polyphenol, and (B) second component comprising a polypeptide, oligopeptide, amino acid, or polyamine. The framework element comprises (a) a polypeptide, oligopeptide, amino acid, or polyamine, (b) a polysaccharide, oligosaccharide, or monosaccharide, or a saccharide conjugate, or (c) a lignin, a lignan or a lignin conjugate. The polyphenol comprises a tannin, a tannic acid, a flavonoid, or a poly-resorcinol. An adhesive precursor composition comprising the first component is also disclosed.

An aqueous adhesive composition and a process for preparing such compositions are disclosed. The composition comprises macromolecular complex comprising (A) a first component comprising (i) a framework element and (ii) a polyphenol, and (B) second component comprising a polypeptide, oligopeptide, amino acid, or polyamine. The framework element comprises (a) a polypeptide, oligopeptide, amino acid, or polyamine, (b) a polysaccharide, oligosaccharide, or monosaccharide, or a saccharide conjugate, or (c) a lignin, a lignan or a lignin conjugate. The polyphenol comprises a tannin, a tannic acid, a flavonoid, or a poly-resorcinol. An adhesive precursor composition comprising the first component is also disclosed.

A biomaterial that includes collagen and an antimicrobial agent such as citric acid is provided herein. The biomaterial may further include a metal, such as silver, and an anionic polysaccharide, such as oxidized regenerated cellulose (ORC). Methods of using the biomaterial in wound therapy and on medical implants, and methods for preparing the biomaterial are also disclosed herein.

A biomaterial that includes collagen and an antimicrobial agent such as citric acid is provided herein. The biomaterial may further include a metal, such as silver, and an anionic polysaccharide, such as oxidized regenerated cellulose (ORC). Methods of using the biomaterial in wound therapy and on medical implants, and methods for preparing the biomaterial are also disclosed herein.