The present disclosure relates to a process for preparing a Lawsonia inermis extract which is rich in Lawsone. It also relates to the extract which may be obtained by said process and to a composition comprising thereof. The disclosure also relates to a method for dying fibers, in particular keratin fibers.

The present invention relates to a process for the preparation, also on an industrial scale, of indocyanine green of formula (I) (ICG, 1 H-benz[e]indole, 2-[7-[1,3-dihydro-1,1-dimethyl-3-(4-sulfobutyl)-2H-benz[e]indol-2-ylidene]-1,3,5-heptatrienyl]-1,1-di-methyl-3-(4-sulfobutyl) hydroxide, inner salt, sodium salt, CAS RN 3599-32-4) with a total impurity content <0.5% and % and single impurity <0.10%, MeOH free, purity determined by a new analytical method HPLC at the wavelength of 254 nm, and the related composition with stable NaI, which is water soluble and has NaI content <2.5%.

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The present invention relates to a valuable product in the form of a flavonoid-containing phenol mixture having intense red coloration and to a method for obtaining a valuable-substance phase, more particularly a red-colored phase, from a native substance mixture.

A process for the preparation of diaminophenothiazinium compounds is described, which allows achieving quickly and effectively a high degree of purity of the same.

The present invention refers to a process for purifying leucoindigo salt solutions, for removal of aromatic amines, particularly aniline and N-methylaniline, comprising: adding to a purification vessel a leucoindigo salt solution containing aromatic amines, said solution in the form of a stationary mass; bubbling with a controlled flow rate an inert gas in the purification vessel, by means of a device submerged at the surface of the stationary mass; injecting with a controlled flow rate a gas purification current into the vessel, by means of a device submerged at the stationary mass; and recovering the purified solution from the vessel. It also refers to the use of inert gas in a process for purifying leucoindigo salt solutions, acting as a gas anti-foaming agent, to reduce foam and chances of product stripping during processing.

The present invention involves an improved process for the preparation of Indocyanine green of Formula (I) having high purity of about 99%, wherein the process comprises steps of reacting 1,1,2-trimethyl-1H-benzo[e]indole with 1,4-butane sulfone in boiling solvent to give 4-(1,1,2-trimethyl-1H-benzo[e]indolium-3-yl)butane-1-sulfonate. Followed by reacting 4-(1,1,2-trimethyl-1H-benzo[e]indolium-3-yl)butane-1-sulfonate of Formula (IV) and N-phenyl-N-((1E,3E,5E)-5-(phenylimino)penta-1,3-dienyl)acetamide of formula (V) in presence of sodium acetate and alcohol; and extracting the title compound formula (I) with an ester solvent. ##STR00001##

The present disclosure provides colorant compounds and methods of isolation of the colorant compounds derived from a reaction of genipin and an amine. The colorant compositions comprise purified compounds (e.g., a purified polymer or a purified dimer) obtained from multiple fractioning by chromatography of the reaction resulting material. The purified polymer or dimer can be used as a colorant by itself or in combination with another colorant for imparting color to a food, a drug, a cosmetic, a medical device, and textile products.

A method of separating oil-soluble pigment and water-soluble pigment from natural material using aerogels characterized in comprising the steps of: (A) immersing a natural material in a leaching solvent to extract a pigment; (B) mixing the leaching solution from which pigment is extracted in step (A) with aerogel to adsorb oil-soluble pigment to aerogels; (C) separating oil-soluble pigment adsorbed on the surface of aerogel in step (B); (D) drying and concentrating the pigment separated in step (C), enhancing a method of separating from natural material the initial substance for pharmaceuticals, food, cosmetics, etc. facilitating a safer and more efficient production process compared to the conventional separation method.

The present invention provides a method for preparing a colour-stable preparation of a magnesium chlorophyllin alkali metal salt or alkali earth metal salt from natural sources of chlorophyll. The invention further provides a colour-stable and substantially pure pigment composition comprising a vibrant green magnesium chlorophyllin in the form of an alkali metal or alkali earth metal salt, e.g. those prepared by the methods of the invention, and the use of the salts and compositions of the invention as colouring agents, in particular as food colouring agents, and as medicaments and disinfectants.

A method for manufacturing an azoic pigment is disclosed, according to an illustrative embodiment of the present invention. The method includes producing slurry of the azoic pigment. The slurry includes primary aromatic amine (PAA). The method further includes the derivatization of the residual PAA in the slurry, followed by encapsulation of the slurry. The slurry is acidified or basified. Finally, the slurry is further processed, thereby forming PAA migration free azoic pigment. The derivatization and encapsulation additively or synergistically reduce the PAA content thereby inhibiting migration of PAA from the pigment into a substrate onto which the pigment is loaded.