A photobioreactor includes one or more annular chambers concentrically positioned about a central axis, and an algae slurry contained within the one or more annular chambers.

A system and method for converting food waste and other biologically-derived waste materials into nutrients for an algal growth system using worms to produce such nutrients is described. In one embodiment, a method for converting food waste into nutrients for an algal growth system using worms includes providing food waste to a container including a plurality of worms. The method also includes collecting castings from the food waste processed by the plurality of worms. The method further includes providing a wash to the container. The wash causes the castings to move to a bottom portion of the container adjacent to a moveable screen. The method includes actuating the moveable screen so that the castings pass through a plurality of holes in the moveable screen. The method also includes providing the passed castings to an algal growth system.

An algae cultivation system may include: a plurality of panels within a cultivation container, positioned along a first axis perpendicular to the gravitational force, wherein a cultivation volume is created between each pair of panels, and wherein the cultivation volumes are fluidly coupled so as to allow horizontal flow therebetween along the first axis; at least one first sparger, to distribute a first fluid into the container at a first operating flow rate; at least one second sparger, to distribute a second fluid into the container at a second operating flow rate; and at least one controller, to control the first operating flow rate and the second operating flow rate. The first operating flow rate may be adapted to allow turbulent mixing the algae in the cultivation container, and the second operating flow rate may be adapted to allow assimilation of materials in a liquid in the cultivation container.

Zebrafish are a powerful model for investigating cardiac repair due to their unique regenerative abilities, scalability, and compatibility with many genetic tools. However, characterizing the regeneration process in live adult zebrafish hearts has proved challenging because adult fish are opaque and explanted hearts in conventional culture conditions experience rapid declines in morphology and physiology. To overcome these limitations, we fabricated a fluidic device for culturing explanted adult zebrafish hearts with constant media perfusion that is also compatible with live imaging. Unlike hearts cultured in dishes for one week, the morphology and calcium activity of hearts cultured in the device for one week were largely similar to freshly explanted hearts. We also cultured injured hearts in the device and used live imaging techniques to continuously record the revascularization process over several days, demonstrating how our device enables unprecedented visual access to the multi-day process of adult zebrafish heart regeneration.

Disclosed herein are platforms, systems, and methods including a cell culture system that includes a cell culture container comprising a cell culture, the cell culture receiving input cells, a cell imaging subsystem configured to acquire images of the cell culture, a computing subsystem configured to perform a cell culture process on the cell culture according to the images acquired by the cell imaging subsystem, and a cell editing subsystem configured to edit the cell culture to produce output cell products according to the cell culture process.

A kit and a method for improving the quality, acceleration of change in and or improving the yield from a bioreaction of a bioreaction mixture. The bioreaction mixture is typically held in an inner space in a vessel, such as a biomanufacturing vessel, with means for movement of the bioreaction mixture and one or more modules are provided to emit one or more electromagnetic fields to which the bioreaction mixture is exposed over a period of time.

A modular incubator includes a housing including one or more fastening mechanisms for attachment to a workstation frame, a platform located at the housing and defining a sample placement area, and a chamber wall structure coupled to the platform. The chamber wall structure is pivotable between a closed position against the platform to form a sample chamber and an open position in which a front end of the chamber wall structure is spaced apart from the platform to allow access to the sample placement area. The modular incubator further includes a lid coupled to and openable from the chamber wall structure to expose at least a portion of the chamber wall structure for viewing.

The present disclosure provides methods and materials for the cultivation and/or propagation of a photosynthetic organism. Such methods may comprise the use of a lamp assembly that comprises a plurality of circuit boards, each comprising at least three edges, arranged in a substantially spherical shape defining an interior lamp assembly volume, wherein the plurality of circuit boards comprise a first planar surface in contact with the interior lamp assembly volume and an opposing second planar surface comprising light emitting diodes (LEDs); and a barrier that surrounds the plurality of circuit boards forming the substantially spherical shape.

A photobioreactor is particularly suited for producing micro-organisms such as microalgae. The photobioreactor is a closed reactor with reactor vessels which have an open top that is closed by a top wall of the photobioreactor and in which a nutrient medium can be held. At least some of the reactor vessels are individual vessels. Adjacent reactor vessels form a gap between a front wall and a rear wall, the gap being closed at the top side by an overflow wall region and having a vessel overflow opening between the adjacent reactor vessels. A lighting element is held in the gap. Each of the reactor vessels has a partition which divides the reactor vessel into a front reactor chamber and a rear reactor chamber. At least one partition through-flow opening between the front and rear reactor chambers is formed in the partition close to the bottom wall.

A culturing device includes a microplate including a plurality of vessels, each of the vessels having a bottom surface having light transmittance and an opening at an upper portion, a lid having light transmittance, and an intermediate plate having light transmittance sandwiched between the lid and the microplate. The intermediate plate has a plurality of convex portions on a surface thereof facing the microplate and provided with a plurality of through holes corresponding to the convex portions that are disposed so that when the intermediate plate and the microplate are overlapped, each of the plurality of convex portions is inserted into each of the plurality of vessels and each of the plurality of through holes coincides with the opening of each of the plurality of vessels. The lid comes into contact with the intermediate plate so as to close the plurality of through holes provided in the intermediate plate.