The invention relates to a sterile connector for the sterile transfer of a liquid medium, in particular a biological medium, from a liquid container (2) into a fluid chamber (3, 3), wherein the sterile connector (1) has a first coupling device (5) and a second coupling device (6). It is proposed that the first coupling device (5) has a fluid inlet (7) and a fluid outlet (8) and also a first cannula (9), the latter having an end which is directed away from the fluid inlet (7) and forms the fluid outlet (8), that the second coupling device (6) has a fluid passage (10) which, in an initial state of the sterile connector (1), is covered axially by a first septum (11), that the fluid outlet (8), in the initial state of the sterile connector (1), is arranged in a hermetically sealed region of the first coupling device (5) and the surface (11a) of the first septum (11) facing axially away from the fluid passage (10) is arranged in a hermetically sealed region of the second coupling device (6), and that, in a fluidic connection process starting from the initial state of the sterile connector (1), a fluidic connection between the fluid inlet (7) and the fluid passage (10) can be produced by the fact that the end of the first cannula (9) forming the fluid outlet (8) pierces the first septum (11) of the second coupling device (6).

A bioprocess vessel includes a flexible bag or substantially rigid container that defines an interior volume and having a bottom surface, the bottom surface being open or containing an aperture therein for the passage of fluid. A pump is secured to the bottom surface of the flexible bag or substantially rigid container. In some embodiments is secured directly to the flexible bag or substantially rigid container. In other embodiments, the pump is secured indirectly the flexible bag or substantially rigid container using, for example, a port that extends through the aperture on the bottom surface. The port or flanged surface may also be integrated into the pump, which is secured to the vessel. An optional mixing adaptor may be provided inside the interior volume of the flexible bag or substantially rigid container and at least partially covers the inlet that leads to the pump.

A culture container linkage device according to the present disclosure includes a first actuator configured to advance or retract needles 32, an actuator holder rotatably provided on a frame and configured to hold the first actuator, a second actuator, and a washer configured to wash the needles. The second actuator rotates the needles via the actuator holder. The needles are configured to be positioned, by the second actuator, at a container-facing position at which the needles face a culture container and a washing-facing position at which the needles face the washer.

The present invention relates in part to devices, systems, and methods for the production and characterization of engineered tissue constructs. The devices and methods generate decellularized tissue constructs that can be recellularized using donor cells for high-throughput studies of organ physiology, and/or organ pathology. The devices and methods can be used with the systems to mechanically and electrically stimulate the engineered tissue constructs under culture or physiological conditions to detect and assess the presence and degree of any organ pathologies.

The invention relates to an incubation system (26) comprising a preferably multilayered carrier (1) and a container (27). The carrier (1) is received in the container (27) in such a way that the container (27) and the carrier (1) are in fluid communication via at least one interface. Furthermore, the carrier (1) is fastened to the container (27) in such a way that the at least one interface for fluid exchange between the container (27) and the carrier (1) is tight.

An energy-saving and environment-friendly garbage disposal box capable of dispersing garbage, applicable to various areas, includes a domestic garbage disposal unit, a recyclable garbage disposal unit and a plastic garbage disposal unit. A pedal mashing device is provided to a rear portion of the domestic garbage disposal unit. The garbage disposal box is covered by solar panels and a computer display. An auto electronic weighing plate is provided to top the garbage disposal box. A set of mashing cutters is disposed inside the garbage disposal box to connect spatially with a fermentation area, and an organic fertilizer area is located under the fermentation area. The recyclable garbage disposal unit is furnished with a garbage entrance at an upper portion thereof and three external drawers corresponding to three recycle chambers. The plastic garbage disposal unit covered by solar panels is furnished thereinside a gravity compression iron and a battery set. The garbage disposal box provided by this patent disclosure and featured in flexible garbage dispersing functions can resolve environmental degradation caused by garbage piling and environmental pollution caused by the current garbage disposal means, and can also provide a possibility to maximize the garbage utilization rate.

A bottle includes a body, a cap mounted to a cap neck of the body. The cap has an outer peripheral portion which is provided with a protrusion. Around the cap, there is provided a position indicator indicating whether the cap is at a correctly closed position, based on the positional relationship between the protrusion and the position indicator.

A tank with a door locking mechanism for use in bioprocessing, and methods of using the door locking mechanism, is provided.

A system may include a base assembly having a top and a bottom restable on a surface, with the base assembly comprising at least one trough having an upper opening into a cavity and a trough holder configured to hold the at least one trough. The system may also include a cover assembly mounted on the base assembly and configured to cover the at least one trough in the holder. The cover assembly may comprise a main cover portion including a cover wall extending over the at least one trough, with at least one aperture extending through the main cover portion and being substantially vertically aligned with the cavity of the at least one trough mounted on the base assembly. The cover assembly may also include a disc pressure portion configured to removably insert into the at least one aperture press against a disc positioned at the aperture of the main cover portion to move the disc toward the cavity of the at least one trough.

A system for algae incubation including a reactor cell adapted to grow algae, a support buoy secured to the reactor cell, and a floating vessel secured to the reactor cell.