Assemblies, systems, and methods for isolation of target material are provided. In various embodiments, an assembly for target material isolation includes a housing having an upper portion and a lower potion together defining an inner chamber. The inner chamber includes a semi-toroidal shape and the semi-toroidal shape defines a longitudinal axis. The assembly further includes one or more fluidic connection from the exterior of the housing to the inner chamber. An isolation material (e.g., polymer wool and/or magnetic beads) may be disposed within the inner chamber. A system includes a configured to fit at least a portion of the housing and releasably couple the assembly. Upon activation of the motor, the assembly may rotate about the longitudinal axis. An angle of the platform may be adjustable to thereby change the angle of the longitudinal axis about which the assembly rotates.

An automated apparatus for enriching the neurogenic exosomes in blood has a reaction frame at a bottom and a movable operation frame above the reaction frame, and a control structure for controlling the operation frame to run according to a preset track and controlling the reaction frame to react according to a set program. The reaction frame has an oscillation incubation structure, a centrifugal structure, a reagent placing structure, a consumable placing structure, a waste placing structure, a sample placing structure, a sample information identification structure, and a post-reaction enriched sample collection structure. The operation frame has a tube body moving structure for moving a tube body among different structures and a liquid taking and adding structure for transferring liquid in the whole process. The reaction frame or the operation frame has an EP tube marking and identification structure used when an EP tube is used for the first time.

A laser processing machine for killing specific cells from a group of cells on a surface of a layer containing an ingredient capable of absorbing laser light, the laser processing machine being configured to: control a laser light source to output laser light at 5 W or less and at a wavelength of 380 nm or greater such that the laser light source is applied to a second area on a second surface of the layer opposed to the first surface; and control an actuator to provide a relative movement between the second area where the laser light is applied and the layer at a rate of 2000 mm/sec or less such that the irradiated second area absorbs energy to generate heat that kills unwanted cells on a first area of the first surface and the laser light does not instantly kill the specific cells on the first area upon irradiation.

A cell culture vessel for use with a laser processing machine, including: a layer containing an ingredient that generates heat upon laser irradiation; the layer kills specific cells from among a group of cells cultured on a first surface of the layer when a second surface of the layer is irradiated with laser light having an output of 5W or less at a wavelength of 380 nm or greater and a relative movement between a second area on the second surface where the laser light is applied and the layer is at a rate of 2000 mm/sec or less such that the second area absorbs energy of the laser light to generate heat that kills the specific cells that are present on a first area of the first surface and the laser light does not instantly kill the specific cells on the first area upon irradiation with the laser light.

An inclined magnetic holder is disclosed, comprising a magnetic base and a centrifuge tube support plate. The centrifuge tube support plate is provided with centrifuge tube support holes. The magnetic base comprises a first bottom plate, a fixing plate provided on the first bottom plate, and two first-side support plates respectively provided at two sides of the fixing plate. Respective top portions of the two first-side support plates are provided with a position-locating slot. A bottom surface of the position-locating slot is configured with an inclined angle. Two ends of the centrifuge tube support plate are respectively provided with a position-locating protruding block for fitting and assembling into the position-locating slot. The centrifuge tube support holes are evenly and linearly distributed on the centrifuge tube support plate. An elastic circular engagement component for holding a centrifuge tube is provided inside the centrifuge tube support holes. A block magnet is fixed to the fixing plate at a location below and corresponding to each of the centrifuge tube support holes. The block magnets below each of the centrifuge tube support holes correspond to each of the centrifuge tubes. A north pole or south pole surface of the block magnet faces the centrifuge tube and is parallel to an axis of the centrifuge tube.

The cell culture system has a culture tank containing a liquid medium that cultures cells, and a cell separator including a hydrodynamic separation device and a liquid feeding unit. The hydrodynamic separation device has a curved flow channel having a rectangular cross-section, and separates relatively large cells from the cells contained in the liquid medium using a vortex flow generated by flow through the curved flow channel. The liquid feeding unit flows the liquid medium through the hydrodynamic separation device in a pressure environment controlled to suppress decrease in cell viability caused by pressure fluctuation in the liquid medium during flowing through the hydrodynamic separation device.

A filtration device that includes a cylindrical body and a filtration part. The cylindrical body has a first open end and a second closed end with an end wall. The filtration part is on a circumferential portion of the cylindrical body and has through-holes.

A system includes an algae bioreactor that contains an algae slurry, a heat exchanger in fluid communication with the algae bioreactor to receive the algae slurry from the algae bioreactor and heat and increase a pressure of the algae slurry, and one or more valves and a flash vessel in fluid communication with a discharge of the heat exchanger to flash the algae slurry and create steam and algae biomass. A separator receives the algae biomass from the flash vessel and separates oils from the algae biomass to generate a biofuel.

A centrifuge microplate fermenter for culturing cells in a nutrient medium wherein the centrifuge microplate fermenter is comprised of a top end, a bottom end, a vertical cylindrical outer wall positioned between the top end and the bottom end, and an inner wall positioned inside the outer wall, the bottom end further comprised of a plurality of baffles which protrude from inner wall toward a theoretical center of the vertical cylindrical outer wall terminating in a conical tip

A centrifuge rotor having a curved shape is offset on a spinning rotor base and creates contiguous areas of low to high centrifugal force depending on the distances from the axis of the rotor base and a method of separating components in a fluid based upon a difference in density of the components, the method comprising the steps of providing to a rotor as described herein the fluid containing the mixed together components to be separated based upon the difference in density of the mixed together components; continuously flowing the components in the fluid to the rotor through an input tube connected to the input port while the rotor is spinning about a centrifugal axis of rotation; separating the components in the fluid into fractions based upon the difference in density of the mixed together components with the use of centrifugal force when the rotor is spinning; collecting components having i) a first density via a first tube connected to the output port at the first end on the rotor, ii) a second density via a second tube connected to the output port at the second end on the rotor, iii) a third density via a third tube connected to the output port at the junction on the rotor and iv) a fourth density via a fourth tube connected to the output port between the input port and the output port at the first end.