A sensor device according to the present technology includes a stack sensor. The stack sensor includes a first sensor layer and a second sensor layer. The first sensor layer has, as a detection target, a first substrate in a culture solution, the first substrate being changed in accordance with a change in a state of a cell. The second sensor layer has, as a detection target, a second substrate in the culture solution and is provided on the first sensor layer, the second substrate being changed in accordance with the change in the state.

The present invention relates to a method for growing aquatic organisms capable of photosynthesis in a controlled aqueous environment and a system for carrying out said method. The invention provides a method and system for growing aquatic organisms capable of photosynthesis under controlled conditions and which uses low energy input.

The invention relates to a method for characterizing the activity of a culture comprising microalgae, the method comprising the steps of: supplying a sample of the culture from a bioreactor to a chamber fluidically connected to the bioreactor; illuminating the sample in the chamber; measuring the concentration of dissolved oxygen in the sample in order to determine a rate of oxygen production by the illuminated sample. The invention also relates to a device and an apparatus for characterizing a culture comprising microalgae.

Provided are systems and methods for spatially and temporally controlling light with an illumination device comprising a light source operably connected to a circuit board, one or more light guide plates, one or more optical masks, a controller, and a computer readable medium, comprising instructions that, when executed by the controller, cause the controller to: illuminate a cell or a substrate with light from the light source, and spatially and temporally control illumination of light to the cell or the substrate with one or more illumination parameters, wherein the one or more light guide plates provides uniform illumination of the light. Also provided herein are methods of screening using the system and/or device of the present disclosure.

Provided is a culture-medium-monitoring apparatus including: an optical measurement unit that includes an illumination light source and a collecting lens that radiate an illumination light onto a culturing liquid, a retroreflective member that has an array in which micro-reflective elements are arrayed, that is disposed so as to sandwich the vessel between the retroreflective member, and the illuminating light source and the collecting lens, and that reflects the illumination light passed through the culturing liquid in the vessel, and a light detector that detects an intensity of the illumination light passed through the culturing liquid in the vessel after being reflected by the retroreflective member; and a control portion that causes the intensity of the illumination light to be repeatedly detected at a prescribed timing, and that determines a state of the culturing liquid on the basis of a change over time in the intensity of the illumination light.

This apparatus (30) for the production of microalgae comprises a vessel (1) intended to receive a culture medium of the microalgae, and a lighting device (6) intended to be positioned in the vessel inside the culture medium. The lighting device (6) is configured to emit light at least in a range of wavelengths useful for the photosynthesis of the microalgae. The apparatus comprises a control system (15) for automatically controlling a power supply of the lighting device (6) so as to adjust the output light intensity of the lighting device (6) according to the concentration of microalgae in the vessel (1).

A deep water drawing step of drawing deep water that exists in a deep region of the sea to a surface region of the sea with an upwelling pipe (1); and a phytoplankton culturing step of culturing the phytoplankton in the upwelling pipe (1) are included to produce, as a basic producer of a food chain, a living marine resource, such as fishes and shellfishes, with phytoplankton produced in the phytoplankton culturing step.

A microalgae culture broth producing system includes a device for culture broth sterilization using a micro bubble generator, an air compression and pressure equalization device for the injection of carbon dioxide and oxygen in the atmosphere into the culture broth. The system also includes an air chilling device to maintain suitable culture broth temperature when water temperature is too high, an automatic carbon dioxide supply device to promote photosynthesis, and a sealed vertical photobioreactor to block out pollutants and increase dissolved carbon dioxide and oxygen concentration. The system further includes a high-efficiency harvesting device using hollow fiber membranes, and a hot air drying device using the waste heat generated by air compression.

A device for storing live algae is disclosed. The device may include: a closed container, at least partially transparent to light, the container is configured to hold live algae aquaculture at a predetermined temperature; at least one light source for providing light to the closed container; a CO.sub.2 source for providing CO.sub.2 to the closed container; an air circulation system for circulating air inside the closed container; and a controller for controlling the at least one light source to illuminate an internal space of the closed container in an amount sufficient to keep the algae aquaculture alive but inhibits reproduction of the algae for at least 4 weeks.

Methods and systems for preparing clonal cell populations are described. In some instances the disclosed methods comprise: a) identifying and selecting a cell based on its position on a surface or in a container, where the selection is not based on whether the cell comprises an exogenous label or an expressed reporter; b) photoablating all non-selected cells on the surface or in the container; and c) growing a clonal population of the selected cell.