C12M45/02

SYSTEM AND METHOD FOR AUTOMATED CELL PROCESSING
20230167398 · 2023-06-01 · ·

The present invention is directed to a system, method, use, and diagnostic kit for cell processing. The invention discloses a cell-quantifying component configured for quantifying the cells in the derived tissue. The cell quantifying component can be configured for quantifying the volume flow in the system. Based on the cell-relevant data generated by at least cell quantification, the operational parameters for cell processing are determined.

Method for cooling and detoxifying biomass
11485988 · 2022-11-01 · ·

The present invention relates to an improved method and device for treating biomass in which thermally treated biomass is discharged from a pressurized reactor and introduced into a blow tank and then a flash tank, wherein the absolute pressure in the blow tank is maintained above atmospheric pressure and the absolute pressure in the flash tank is maintained below atmospheric pressure. The slurry of biomass separated in the flash tank is then enzymatically treated. The heat from the thermally treated biomass is recovered from the latent heat of a vaporous aqueous stream withdrawn from the blow tank.

Cell Surface Marker Depletion in a Sample Processing Device

The disclosure provides methods, devices, and kits for conducting a quantitative analysis of a whole blood sample. Various modifications to the disclosed methods, devices, and kits are described.

Tissue processing apparatus, a filter and a method for processing tissue therefrom
11667877 · 2023-06-06 ·

A tissue processing apparatus, a filter and a method for processing tissue therefrom #! The problem to be solved is to provide a portable apparatus for processing harvested fat to form a good quality graft that does not clog syringes, and the problem is solved by providing an apparatus as in the present invention with a filter that is inclined to the base of the apparatus and comprises of plurality of elongated protrusion that are structured at an angle on the surface of the filter and blocks the fibres when the harvested fat moves on the inclined surface of the filter, thereby filtering the harvested fat and avoiding clogging of syringes.

Method for dissociating cell aggregates

A method for dissociating cell aggregates in an agitated reactor. The method comprises providing a cell culture comprising cell aggregates in the agitated reactor, contacting the cell aggregates with a dissociation reagent, generating a dissociation force in the agitated reactor and exposing the contacted cell aggregates to the generated dissociation force under conditions sufficient to dissociate the contacted cell aggregates. The method may be used in a process for passaging cells and/or generating dissociated differentiated cells from stem and/or progenitor cells.

Microfluidic tissue dissociation device and method

A tissue dissociation device includes an inlet coupled to a first stage having a single channel having an upstream end and a downstream end; a plurality of serially arranged intermediate stages, wherein a first intermediate stage of the plurality is fluidically coupled to the downstream end of the first stage, and wherein each subsequent intermediate stage of the plurality has an increasing number of channels (with channels of smaller dimensions); and an outlet coupled to a last stage of the intermediate stages.

System and method for separating high value by-products from grains used for alcohol production
09732302 · 2017-08-15 ·

Systems and methods are provided for separating high value by-products, such as oil and/or germ, from grains used for alcohol production. In one embodiment, a method for separating by-products from grains used for alcohol production includes, subjecting milled grains to liquefaction to provide a liquefied starch solution including fiber, protein, and germ. The germ is separated from the liquefied starch solution. The separated germ is ground, e.g., to a particle size less than 50 microns, to release oil to provide a germ/oil mixture. Then, prior to fermentation, the oil is separated from the germ/oil mixture to yield an oil by-product. The pH of the germ/oil mixture can be adjusted to about 8 to about 10.5 and/or cell wall breaking enzymes or chemicals may be added to help release oil from the germ. In one example, the oil yield is greater than 1.0 lb/Bu.

Intelligent Microbial Sample Treatment System

An intelligent microbial sample treatment system includes a workbench, and a sample treatment assembly, a culture medium treatment assembly, a streaking assembly and a culture medium storage assembly that are disposed on the workbench; the sample treatment assembly comprises a sample transfer device, a filling device, and a scanning device, a weight detection device, a filling location, a shaking device and waiting locations that are disposed in sequence; and the sample transfer device moves a sample cup among the scanning device, the weight detection device, the filling location, the shaking device and the waiting locations. The intelligent microbial sample treatment system disclosed by the present invention enables improvement of work efficiency and reduction of space occupation and has a reasonable structural layout and high work efficiency.

Organic Waste Digester System
20170226466 · 2017-08-10 ·

An organic waste digester system is provided. The system includes a heated hopper unit within the housing to receive organic waste. An agitation mechanism mixes the organic waste along with a microbe mixture to aid breakdown of the waste. Liquefied organic waste is discharged through an outlet and conveyed to a drying unit downstream of the hopper unit. The drying unit includes a microwave dryer unit.

System and method for processing of biological tissue samples

The present disclosure provides an automated system for processing of tissue. The system comprises a plurality of containers for storing at least one of tissue samples, buffer solutions, enzymes and other reagents, tissue processing container for processing of the tissue, and a robotic assembly coupled to the tissue processing container. The robotic assembly is configured to: carry the tissue processing container towards each of the plurality of containers, and align an inlet port of the tissue processing container with an outlet port of each of the plurality of containers for collecting the liquids, and moves the tissue processing container in multiple-planes to perform at least one of the washing processes, digestion process, phase separation process and combination thereof. The system also comprises of a control unit interfaced with the robotic assembly for controlling operations of the robotic assembly while processing the tissue.