Disclosed are an automated nucleic acid extraction method and device. The device includes a base body, a cassette, a driving unit, a moving frame and a syringe. The base body comprises a sample accommodating area, a column accommodating area, a cassette accommodating area and a collection tube being arranged in a linear direction. The cassette is arranged in the cassette accommodating area and includes two parallel walls and at least two vertical walls. The parallel walls and the vertical walls jointly form a lysis buffer well, at least one wash buffer well and an elution buffer well. Each vertical wall includes a load-bearing abutment. The driving unit and the moving frame are arranged on the base body. The syringe is arranged on the moving frame and is driven by the driving unit to reciprocate along with the moving frame in the linear direction.

The current disclosure concerns a method for decontaminating a virus production system, wherein virus particles are produced in at least one bioreactor and purified from liquids comprising said virus particles thereby generating liquid waste, said method comprising the step of exposing said system or a part thereof to heated air and/or liquid at a temperature of at least 60° C. after viral production took place, thereby eradicating remaining virus particles in said system. In a second and third aspect the current disclosure concerns a virus production system wherein the system comprises a heating device suitable for heating air and/or liquid to a temperature of at least 60° C., and the use of such a system for the production of viruses and/or viral vaccines.

A portable and mobile bioprocessing system and method for protein manufacturing that is compact, integrated and suited for on-demand production of any type of proteins and for delivery of the produced proteins to patients or for assay purposes. The portable system and method can also be used for efficient on-demand production of any type of protein with point-of-care delivery.

A portable and mobile bioprocessing system and method for protein manufacturing that is compact, integrated and suited for on-demand production of any type of proteins and for delivery of the produced proteins to patients or for assay purposes. The portable system and method can also be used for efficient on-demand production of any type of protein with point-of-care delivery.

The present invention provides a system for the capture and purification CO.sub.2 and a purification unit for said system, wherein said purification unit comprises: a first filter having a first container and a first filler material; a second filter having a second container and a second filler material, downstream of said first filter; a third filter having a third container and a third filler material, downstream of said second filter, said third filter having, additionally, a heating element thermally coupled to said third filler material; and control means of said heating element; wherein said first filler material is silica; wherein said second filler material is zeolite; and wherein said third filler material is a metal-organic framework modified with activated carbon.

An improved fluid filtration system is described. The system uses improved sensor assemblies to avoid the problem of biomass build up and reduce the holdup volume of liquid outside of the process vessel. It significantly enhances the performance, robustness and consistency of the filtration.

The present invention provides a system for recovering protein in a production process of an ultrahigh maltose syrup, including a saccharification tank, an enzyme preparation tank, a first plate heat exchanger, a second plate heat exchanger, a plate and frame filter, a buffer tank and a rotary drum filter. The present invention further provides a method of recovering protein by using the system. After the sugar liquid in the saccharification tank is stood, the protein floats at the upper part of the saccharification tank and the lower liquid is clear and transparent and thus the sugar liquid can be directly filtered. When the saccharification tank is discharged, the lower liquid is firstly discharged with the remaining liquid being bottoms containing protein. During a production process, enzymatic hydrolysis is performed for the sugar liquid containing protein before filtration to improve the filtration effect of the sugar liquid. Assisted by the plate and frame filter, protein can be recovered. The present invention improves the economic benefits, reduces the production costs, and thus solves the problem of difficulty in recovering protein in a production process of an ultrahigh maltose syrup.

Disclosed herein is a perfusion filtration module or bioreactor for filtering a fluid, wherein the filtration module or bioreactor has a plurality of hollow fiber filter membranes that are splayed to reduce fouling of the filtration array.

The present invention pertains to methods for manufacturing high titer antibody products. In particular, the invention pertains, in part, to improved serum-free animal cell culture medium, which can used for the production of a protein of interest. Additionally, the present invention further pertains to chromatographic procedures employed to successfully isolate the antibody product subject of the present disclosure.

A system and method for producing cellulosic ethanol by biomass saccharification and fermentation is provided. The system includes a first reactor configured to carry out an enzymatic hydrolysis reaction of a biomass feedstock, a second reactor configured to carry out a fermentation reaction of the biomass feedstock, and a collection tank configured to collect the cellulosic ethanol. The first reactor and second reactor are provided with an enzymatic hydrolysis dosing pipe and a fermentation dosing pipe, respectively. An outlet of the first reactor is connected to an inlet of the second reactor through a fermentation pipe. An outlet of the second reactor is connected to an inlet of the first reactor through a discharge pipe that is provided with a first discharge pipe configured to discharge material from the second reactor. The first reactor is connected to an inlet of the collection tank through an ethanol pipe.