An object is to provide a composition and a method for eliminating undifferentiated pluripotent stem cells remaining in a cell group induced to differentiate from pluripotent stem cells. It has been found that while dihydroorotate dehydrogenase inhibitors exhibit cytotoxic activity against pluripotent stem cells, they do not exhibit significant cytotoxic activity against differentiated cells such as somatic stem cells.

The present invention relates to a living fatty material from which immunity is removed, and a method for manufacturing the same, and more specifically, to a living fat tissue from which immunity is removed and to a method for manufacturing the same, comprising the steps of collecting fat tissues; irradiating the fat tissues with 20 to 500 kGy of gamma (γ) rays; and applying centrifugal separation of the fat tissues irradiated with gamma rays.

The present invention provides a sperm sorting chip and a method for sorting sperm using the same. Said sperm sorting chip includes: a flow channel structure sequentially configured with a gradually diverging flow field region, a main flow channel, and a gradually converging main flow channel intercommunicated with each other from a first side end to a second side end; a fluid injection port, a semen injection port, and a semen extraction port separately located at the first side end and communicated with a main input channel of the gradual diverging flow field region; and a waste fluid outlet located at the second side end and communicated with the gradually converging main flow channel. The gradually diverging flow field region further includes a plurality of sub-input channels derived from the main input channel and converged into the main flow channel, and the plurality of sub-input channels have a gradually widening channel width at the junction with the main flow channel. By contrast, the gradually converging main flow channel has a gradually narrowing channel width toward the waste fluid outlet.

Disclosed herein are platforms, systems, and methods including a cell culture system that includes a cell culture container comprising a cell culture, the cell culture receiving input cells, a cell imaging subsystem configured to acquire images of the cell culture, a computing subsystem configured to perform a cell culture process on the cell culture according to the images acquired by the cell imaging subsystem, and a cell editing subsystem configured to edit the cell culture to produce output cell products according to the cell culture process.

The present invention relates to a method for isolating bona fide pancreatic progenitor cells and to cell populations enriched for bona fide pancreatic progenitor cells.

The present invention provides a cell treatment apparatus that can improve the operating rates of an observation unit and a laser irradiation unit in the case of treating a plurality of cell culture vessels. The cell treatment apparatus of the present invention includes: a cell treatment chamber in which cells in a cell culture vessel are treated; an observation unit that can observe the cells in the cell culture vessel; a laser irradiation unit that can irradiate the cells with lasers; a first moving unit that can move the observation unit; and a second moving unit that can move the laser irradiation unit, wherein the cell treatment chamber includes a plurality of regions in which the cells can be treated, each region includes a first cell culture vessel placement unit and a second cell culture vessel placement unit, in the first cell culture vessel placement unit, the cells in the cell culture vessel are observed by the observation unit, in the second cell culture vessel placement unit, the cells in the cell culture vessel are irradiated with lasers by the laser irradiation unit, the observation unit is moved by the first moving unit in a state of being able to observe the cells in the cell culture vessel in the first cell culture vessel placement unit of each region, and the laser irradiation unit is moved by the second moving unit in a state of being able to irradiate the cells in the cell culture vessel in the second cell culture vessel placement unit of each region with lasers.

A method for preparing a cell membrane-coated nano topological array and a use thereof are disclosed. The method includes: stimulating macrophages to form stimulated macrophages, and extracting the membrane of the stimulated macrophages; at the same time, processing a substrate to form a substrate with nanowires, and treating the substrate with nanowires to form a positively charged nanowire substrate; combining the membrane of the stimulated macrophages with the positively charged nanowire substrate to obtain a macrophage membrane-modified nano topological array. The present invention is simple in preparation and operation, and can be applied to capture bacteria.

Provided is a DNT cell population with IL-17 secretory cells removed and a preparation method therefor and the use thereof. The DNT cell population has the effects of inhibiting T cell proliferation and inducing apoptosis, can inhibit the inflammation of adipose tissue, improve insulin resistance, alleviate diabetes, and relieve steatohepatitis, and can also be used for preventing and treating antigen-specific allergic asthma.

According to one embodiment, a pluripotent stem cell manufacturing system includes processing circuitry. The processing circuitry acquires storage information for the storage of a sample from a donor, and surviving cell number information for the number of surviving cells contained in the sample. The processing circuitry estimates tissue stem cell number information for the number of tissue stem cells contained in the sample, based on the storage information and the surviving cell number information.

The present invention relates to apparatuses for use in electrophoretic separation of macromolecules and/or cells.