C12Q1/54

Chemically patterned microfluidic paper-based analytical device (C-μPAD) for multiplex analyte detection

Disclosed is a device and method for a microfluidic paper-based analytical device (μPAD), for low-cost and user-friendly analytical devices capable of use for disease screening, point-of-care pathogen and biomarker detection, food and water quality testing. A microfluidic paper-based analytical device is further produced by chemical vapor deposition for multiplex heavy metal detection in water. Assay demonstrations proved that the immobilization of functional groups and multiplex heavy metal detection is suitable for real-world applications and established the approach for DNA analysis. The disclosed invention comprises multilayer capability, including the ability for various biomolecules to be immobilized with charge interaction.

MEDICAL DIAGNOSTIC DEVICES AND METHODS

A medical diagnostic device includes a wirelessly transmitted time data receiver and processor. Associated devices, methods and functionality are also described.

MEDICAL DIAGNOSTIC DEVICES AND METHODS

A medical diagnostic device includes a wirelessly transmitted time data receiver and processor. Associated devices, methods and functionality are also described.

PERSONAL HYGIENE WIPE WITH INTEGRAL URINE GLUCOSE DETECTION FEATURE
20220323311 · 2022-10-13 ·

A personal hygiene wipe with an integral urine glucose detection feature. The wipe includes a substrate that is adapted for impregnation with a composition having one or more drying, cleaning, odor control, or antibacterial properties. The wipe also is saturated with a chemical composition for detecting glucose in urine. When glucose is detected, the wipe turns to a different color.

Apparatus to Detect Salt Concentrations and Glucose in Bodily Fluids
20230060490 · 2023-03-02 ·

The present development is a method and device to monitor the salt level in a patient's blood without the need of laboratory facilities or intervention by medical personnel. The basic device is designed to measure the concentration of analytes, specifically sodium ion and potassium ion, in the patient's blood and to communicate the analyte level to the patient essentially instantaneously through a mobile monitor or display screen. In a variation, the device combines the analyte-concentration measuring function with a means for measuring the concentration of glucose in blood, and the blood analyte level and glucose level are displayed to the patient essentially instantaneously. Both the salt level device and the salt level+glucose level device may be further adapted to allow for the salt and glucose level data to be stored in a data storage base so the patient has an historical record of the concentration levels.

Apparatus to Detect Salt Concentrations and Glucose in Bodily Fluids
20230060490 · 2023-03-02 ·

The present development is a method and device to monitor the salt level in a patient's blood without the need of laboratory facilities or intervention by medical personnel. The basic device is designed to measure the concentration of analytes, specifically sodium ion and potassium ion, in the patient's blood and to communicate the analyte level to the patient essentially instantaneously through a mobile monitor or display screen. In a variation, the device combines the analyte-concentration measuring function with a means for measuring the concentration of glucose in blood, and the blood analyte level and glucose level are displayed to the patient essentially instantaneously. Both the salt level device and the salt level+glucose level device may be further adapted to allow for the salt and glucose level data to be stored in a data storage base so the patient has an historical record of the concentration levels.

BIOSENSOR, CHANNEL MEMBER USED IN BIOSENSOR, AND METHOD OF USING BIOSENSOR
20220333150 · 2022-10-20 · ·

A biosensor includes: a flow channel through which a liquid sample flows, the liquid sample containing a specific component; a holding sheet that is disposed in the flow channel and holds a substance corresponding to the specific component; and a first temperature sensor that is disposed to correspond to the holding sheet and detects a reaction heat generated by a contact reaction between the specific component and the corresponding substance. The biosensor acquires information on the specific component based on the reaction heat.

SENSING PLATFORM

Sensors comprising B-L-S; wherein: B is a biomolecule comprising one or more surface-exposed thiol moieties, L is a thiol reactive linking group, and S is a substrate; wherein L is covalently linked to B via the one or more surface-exposed thiol moieties.

SENSING PLATFORM

Sensors comprising B-L-S; wherein: B is a biomolecule comprising one or more surface-exposed thiol moieties, L is a thiol reactive linking group, and S is a substrate; wherein L is covalently linked to B via the one or more surface-exposed thiol moieties.

COMPOSITION FOR URINE GLUCOSE DETECTION AND SYSTEM FOR IDENTIFYING URINE GLUCOSE BY USING SAME
20220315980 · 2022-10-06 ·

A composition for urine glucose detection includes a fixing agent, an indicator and glucose oxidase, wherein the fixing agent includes one or more selected from the group consisting of a soap base, gelatin, and natural fatty acids.