A linearity standard includes a plurality of calibration solutions, each calibration solution having a different level of a reactant having a known response in a test strip and meter combination, and an electronic storage medium for storing calibration instructions and known responses for each solution of the plurality of calibration solutions.

A linearity standard includes a plurality of calibration solutions, each calibration solution having a different level of a reactant having a known response in a test strip and meter combination, and an electronic storage medium for storing calibration instructions and known responses for each solution of the plurality of calibration solutions.

A disposable sensor chip for biological component concentration measurement includes: a chip main body defining a cavity through which a body fluid is flowable; and a reagent located in the cavity such that the body fluid flowing through the cavity comes into contact with the reagent. The reagent comprises a 2-substituted benzothiazolyl-3-substituted phenyl-5-substituted sulfonated phenyl-2H-tetrazolium salt.

A disposable sensor chip for biological component concentration measurement includes: a chip main body defining a cavity through which a body fluid is flowable; and a reagent located in the cavity such that the body fluid flowing through the cavity comes into contact with the reagent. The reagent comprises a 2-substituted benzothiazolyl-3-substituted phenyl-5-substituted sulfonated phenyl-2H-tetrazolium salt.

The present invention relates to a method for measuring the cholesterol uptake capacity of lipoproteins. The present invention also relates to a reagent kit for measuring the cholesterol uptake capacity of lipoproteins. The present invention further relates to a tagged cholesterol which can be used in the method and the reagent kit.

The present invention relates to a method for measuring the cholesterol uptake capacity of lipoproteins. The present invention also relates to a reagent kit for measuring the cholesterol uptake capacity of lipoproteins. The present invention further relates to a tagged cholesterol which can be used in the method and the reagent kit.

To provide a method for simply and precisely measuring cholesterol (LDL-C) in low-density lipoprotein in a sample without use of any surfactant having an alkylphenol structure, in terms of environmental friendliness. A method for measuring LDL-C in a sample, the method comprising: reacting the sample with (i) a combination of cholesterol ester hydrolase and cholesterol oxidase or (ii) a combination of cholesterol ester hydrolase, an oxidized coenzyme and cholesterol dehydrogenase, in an aqueous solvent which comprises: [a] one or more surfactants selected from the group consisting of a polyoxyethylene alkyl ether and a polyoxyethylene polyoxypropylene alkyl ether; and [b] a polyoxyethylene polyoxypropylene copolymer; and which does not comprise any surfactant having an alkylphenol structure; and measuring a substance formed or consumed in the reaction.

To provide a method for simply and precisely measuring cholesterol (LDL-C) in low-density lipoprotein in a sample without use of any surfactant having an alkylphenol structure, in terms of environmental friendliness. A method for measuring LDL-C in a sample, the method comprising: reacting the sample with (i) a combination of cholesterol ester hydrolase and cholesterol oxidase or (ii) a combination of cholesterol ester hydrolase, an oxidized coenzyme and cholesterol dehydrogenase, in an aqueous solvent which comprises: [a] one or more surfactants selected from the group consisting of a polyoxyethylene alkyl ether and a polyoxyethylene polyoxypropylene alkyl ether; and [b] a polyoxyethylene polyoxypropylene copolymer; and which does not comprise any surfactant having an alkylphenol structure; and measuring a substance formed or consumed in the reaction.

A 2-substituted benzothiazolyl-3-substituted phenyl-5-substituted sulfonated phenyl-2H-tetrazolium salt represented by the following Formula (1): ##STR00001##
wherein, R.sup.1 can be a hydrogen atom, a hydroxyl group, a methoxy group, and an ethoxy group; R.sup.2 can be a nitro group, OR.sup.4, and a carboxyl group; R.sup.3 is a hydrogen atom, a methyl group, or an ethyl group, while at least one is a methyl group or an ethyl group; R.sup.4 is a methyl group or an ethyl group; m is 1 or 2; n is an integer from 0 to 2; p is 0 or 1; n+p is 1 or greater; q is 1 or 2; when q is 2, the OR.sup.3's are disposed adjacently to each other and may form a ring; and X is a hydrogen atom or an alkali metal atom.

A 2-substituted benzothiazolyl-3-substituted phenyl-5-substituted sulfonated phenyl-2H-tetrazolium salt represented by the following Formula (1): ##STR00001##
wherein, R.sup.1 can be a hydrogen atom, a hydroxyl group, a methoxy group, and an ethoxy group; R.sup.2 can be a nitro group, OR.sup.4, and a carboxyl group; R.sup.3 is a hydrogen atom, a methyl group, or an ethyl group, while at least one is a methyl group or an ethyl group; R.sup.4 is a methyl group or an ethyl group; m is 1 or 2; n is an integer from 0 to 2; p is 0 or 1; n+p is 1 or greater; q is 1 or 2; when q is 2, the OR.sup.3's are disposed adjacently to each other and may form a ring; and X is a hydrogen atom or an alkali metal atom.