Patent classifications
C07C51/418
Method of obtaining complex acidic salts of divalent metals and dicarboxylic acids
A method of obtaining a complex acidic salt of a divalent metal and a dicarboxylic acid includes heating water in a reactor; adding a dicarboxylic acid to the heated water; stirring the water to dissolve the dicarboxylic acid in the heated water to produce a solution or a suspension of the dicarboxylic acid in the heated water; adding MeO to the solution or the suspension, where Me is a divalent metal; continuing the stirring of the solution or suspension until formation of the complex acidic salt Me(AcH).sub.2.nH.sub.2O begins, where Ac is an anion of the dicarboxylic acid, and n=0-8; cooling the complex acidic salt to below a temperature of crystallization; sedimenting the complex acidic salt; filtering the complex acidic salt to remove water from the complex acidic salt; and drying the complex acidic salt.
Method of obtaining complex acidic salts of divalent metals and dicarboxylic acids
A method of obtaining a complex acidic salt of a divalent metal and a dicarboxylic acid includes heating water in a reactor; adding a dicarboxylic acid to the heated water; stirring the water to dissolve the dicarboxylic acid in the heated water to produce a solution or a suspension of the dicarboxylic acid in the heated water; adding MeO to the solution or the suspension, where Me is a divalent metal; continuing the stirring of the solution or suspension until formation of the complex acidic salt Me(AcH).sub.2.nH.sub.2O begins, where Ac is an anion of the dicarboxylic acid, and n=0-8; cooling the complex acidic salt to below a temperature of crystallization; sedimenting the complex acidic salt; filtering the complex acidic salt to remove water from the complex acidic salt; and drying the complex acidic salt.
ALKALINE EARTH METAL SALTS
A composition may include an alkaline earth metal salt. The alkaline earth metal salt may have an angle of repose less than or equal to about 34. The alkaline earth salt may be used to form a tablet. The tablet may have a friability less than or equal to about 1%. A method of forming an alkaline earth metal salt may include providing a slurry that includes an alkaline earth metal and an organic polyatomic anion, and spray drying the slurry to form a spray dried alkaline earth metal salt. The slurry temperature may be greater than or equal to about 50° C. A method of forming a tablet may include tableting a non-agglomerated alkaline earth metal salt.
ALKALINE EARTH METAL SALTS
A composition may include an alkaline earth metal salt. The alkaline earth metal salt may have an angle of repose less than or equal to about 34. The alkaline earth salt may be used to form a tablet. The tablet may have a friability less than or equal to about 1%. A method of forming an alkaline earth metal salt may include providing a slurry that includes an alkaline earth metal and an organic polyatomic anion, and spray drying the slurry to form a spray dried alkaline earth metal salt. The slurry temperature may be greater than or equal to about 50° C. A method of forming a tablet may include tableting a non-agglomerated alkaline earth metal salt.
METHOD FOR PRODUCING AN ADSORBENT FROM ORGANOMETALLIC FRAMEWORK STRUCTURES (MOF)
The present invention relates to a method for the production of an absorbent made of metal-organic framework structures (MOF), in the case of which at least one metal salt is converted with at least one organic ligand. The conversion is effected at a temperature greater than 100° C. in a solvent mixture which comprises DMSO and water. The invention relates in addition to an adsorbent produced with the method according to the invention or to a substrate coated with such an adsorbent and also to possibilities of use of such an adsorbent or substrate.
ITACONIC ACID DERIVATIVES AND USES THEREOF INTREATING AN INFLAMMATORY DISEASE OR A DISEASE ASSOCIATED WITH AN UNDESIRABLE IMMUNE RESPONSE
The invention relates to compounds of formula (IW-1) and to their use in treating or preventing an inflammatory disease or a disease associated with an undesirable immune response: wherein R.sup.A, R.sup.B, R.sup.C and R.sup.D are as defined herein.
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ITACONIC ACID DERIVATIVES AND USES THEREOF INTREATING AN INFLAMMATORY DISEASE OR A DISEASE ASSOCIATED WITH AN UNDESIRABLE IMMUNE RESPONSE
The invention relates to compounds of formula (IW-1) and to their use in treating or preventing an inflammatory disease or a disease associated with an undesirable immune response: wherein R.sup.A, R.sup.B, R.sup.C and R.sup.D are as defined herein.
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HIGH ASPECT RATIO LAYERED DOUBLE HYDROXIDE MATERIALS AND METHODS FOR PREPARATION THEREOF
Embodiments are directed to adamantane-intercalated layered double-hydroxide (LDH) particles and the methods of producing adamantane-intercalated LDH particles. The method comprises adding to an aqueous solution a first precursor and a second precursor to form an initial mixture, where the first precursor is Al(OH).sub.3 or Al.sub.2O.sub.3, the second precursor is a hydroxide M(OH).sub.2 or an oxide MO, where M is a metal of oxidation state +2; and the initial mixture has a M/Al molar ratio of from 1 to 5. The method also comprises adding to the initial mixture an amount of adamantane to form a reaction mixture having an Al/adamantane molar ratio of from 0.5 to 2; and heating the reaction mixture to produce adamantane-intercalated LDH particles, where the adamantane-intercalated LDH particles have aspect ratios greater than 100.
SYNTHESIS OF MAGNESIUM ADAMANTANE SALTS AND MAGNESIUM OXIDE NANOCOMPOSITES, AND SYSTEMS AND METHODS INCLUDING THE SALTS OR THE NANOCOMPOSITES
A method for preparing a magnesium adamantane carboxylate salt is provided. The method includes mixing a magnesium salt and a diamondoid compound having at least one carboxylic acid moiety to form a reactant mixture and hydrothermally treating the reactant mixture at a reaction temperature for a reaction time to form the magnesium adamantane carboxylate salt.
Synthesis of MOFs
The present invention relates to the synthesis of a variety of metal organic frameworks (MOFs) using low temperature and solvents which are considered to be not particularly harmful to the environment. There is also provided novel MOFs which may be made by the desired processes.