Methods, systems, compositions, and devices for the manufacturing of high-quality building blocks, such as polynucleotides, are described herein. Processes described herein provide for efficient washing of residual reagents, solvents, or byproducts from previous synthetic steps to allow for the generation of polynucleotides with low error rates. Processes described herein also provide for reduction in deletion rates during chemical nucleic acid synthesis. Further, methods and devices described herein allow for the rapid construction and assembly of large libraries of highly accurate polynucleotides.

##STR00001##

A compound having the structure of Formula I: wherein m=2 and n is an odd-number between 4 and 20, or a derivative thereof, or a salt, or a prodrug thereof, and a compound having the structure of Formula II: wherein m and n are independently an integer between 2 and 20, or a derivative thereof, or a salt, or a prodrug thereof are described. Compositions and methods of use of the compounds for therapeutically modulating peroxisome proliferator-activated receptors (PPARs) are also provided

##STR00001##

A compound having the structure of Formula I: wherein m=2 and n is an odd-number between 4 and 20, or a derivative thereof, or a salt, or a prodrug thereof, and a compound having the structure of Formula II: wherein m and n are independently an integer between 2 and 20, or a derivative thereof, or a salt, or a prodrug thereof are described. Compositions and methods of use of the compounds for therapeutically modulating peroxisome proliferator-activated receptors (PPARs) are also provided

Processes and facilities for producing a recycled content organic chemical compound directly or indirectly from waste plastic. Processing schemes are described herein for converting waste plastic (or hydrocarbon having recycled content derived from waste plastic) into useful intermediate chemicals and final products. In some aspects, recycled content aromatics (r-aromatics) can be processed to provide recycled content paraxylene (r-paraxylene), which can then be used to provide recycled content dimethyl terephthalate (r-DMT). The r-DMT can then be used to form a variety of other chemical and end products, including recycled content cyclohexanedimethanol (r-CHDM) and various recycled content polymers, such as polyesters and aramid polymers.

Processes and facilities for producing a recycled content organic chemical compound directly or indirectly from waste plastic. Processing schemes are described herein for converting waste plastic (or hydrocarbon having recycled content derived from waste plastic) into useful intermediate chemicals and final products. In some aspects, recycled content aromatics (r-aromatics) can be processed to provide recycled content paraxylene (r-paraxylene), which can then be used to provide recycled content dimethyl terephthalate (r-DMT). The r-DMT can then be used to form a variety of other chemical and end products, including recycled content cyclohexanedimethanol (r-CHDM) and various recycled content polymers, such as polyesters and aramid polymers.