C07C65/105

APPLYING HANSEN SOLUBILITY PARAMETERS TO METAL-ORGANIC FRAMEWORK SYNTHESIS CONDITIONS
20210053903 · 2021-02-25 ·

A method suitable for use in investigating synthesis conditions for metal-organic frameworks may include: identifying synthesis conditions that includes a first solvent system by which a metal-organic framework is successfully synthesized; and synthesizing the metal-organic framework under substantially the same synthesis conditions but with a second solvent system (or a comparable solvent system) having a difference (R.sub.a) between Hansen solubility parameters of 5 MPa.sup.0.5 or less as compared to the first solvent system.

Preparation and Purification of Biphenyldicarboxylic Acids

Processes are described for purifying a biphenyldicarboxylic acid product containing one or more impurities, particularly at least formylbiphenylcarboxylic acid. In the processes, a mixture comprising the biphenyldicarboxylic acid product is contacted with hydrogen in the presence of a hydrogenation catalyst under conditions to selectively reduce at least part of the formylbiphenylcarboxylic acid to produce a hydrogenation effluent comprising (i) hydroxymethylbiphenylcarboxylic acid and/or methylbiphenylcarboxylic acid, and (ii) biphenylcarboxylic acid. At least a portion of the biphenyldicarboxylic acid is then separated from the hydrogenation effluent. Advantageously, a polyester product may be produced from the separated biphenyldicarboxylic acid.

Preparation and Purification of Biphenyldicarboxylic Acids

Processes are described for purifying a biphenyldicarboxylic acid product containing one or more impurities, particularly at least formylbiphenylcarboxylic acid. In the processes, a mixture comprising the biphenyldicarboxylic acid product is contacted with hydrogen in the presence of a hydrogenation catalyst under conditions to selectively reduce at least part of the formylbiphenylcarboxylic acid to produce a hydrogenation effluent comprising (i) hydroxymethylbiphenylcarboxylic acid and/or methylbiphenylcarboxylic acid, and (ii) biphenylcarboxylic acid. At least a portion of the biphenyldicarboxylic acid is then separated from the hydrogenation effluent. Advantageously, a polyester product may be produced from the separated biphenyldicarboxylic acid.

CARBOXYLATED POLYPHENOL DERIVATIVES AND THEIR COSMETIC USE
20200197275 · 2020-06-25 · ·

A subject matter of the present invention is the cosmetic use of at least one compound of formula (I):

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in which:

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denotes a divalent radical chosen from a carbon-carbon single bond *CH.sub.2CH.sub.2* or double bond *CHCH*, of Z or E configuration or their mixtures, b=0 or 1, c=0 or 1, d=0, 1 or 2, and R and R independently denote a hydrogen atom, a linear C.sub.1-C.sub.6 alkyl radical or a branched C.sub.3-C.sub.6 alkyl radical, to treat and/or prevent signs of aging and/or of photoaging of keratinous substances, preferably of the skin, and/or to depigment, lighten and/or whiten keratinous substances, preferably the skin.

The present invention also relates to novel compounds and to a corresponding cosmetic method.

CARBOXYLATED POLYPHENOL DERIVATIVES AND THEIR COSMETIC USE
20200197275 · 2020-06-25 · ·

A subject matter of the present invention is the cosmetic use of at least one compound of formula (I):

##STR00001##

in which:

##STR00002##

denotes a divalent radical chosen from a carbon-carbon single bond *CH.sub.2CH.sub.2* or double bond *CHCH*, of Z or E configuration or their mixtures, b=0 or 1, c=0 or 1, d=0, 1 or 2, and R and R independently denote a hydrogen atom, a linear C.sub.1-C.sub.6 alkyl radical or a branched C.sub.3-C.sub.6 alkyl radical, to treat and/or prevent signs of aging and/or of photoaging of keratinous substances, preferably of the skin, and/or to depigment, lighten and/or whiten keratinous substances, preferably the skin.

The present invention also relates to novel compounds and to a corresponding cosmetic method.

RESIST COMPOSITION, METHOD OF FORMING RESIST PATTERN, AND COMPOUND

A resist composition including a base material component (A) whose solubility in a developing solution is changed due to the action of an acid, and a compound (D0) formed of an anion moiety and a cation moiety which is represented by Formula (d0), in which the cation moiety of the compound (D0) has a Log P value of less than 7.7. In the formula, M.sup.m+ represents an m-valent organic cation, R.sup.d0 represents a substituent, p represents an integer of 0 to 3, q represents an integer of 0 to 3, n represents an integer of 2 or greater, and a relationship of n+p(q2)+5 is satisfied.

##STR00001##

Preparation of phenyl compounds

The invention relates to a method for preparing a compound comprising two phenyl groups by reacting a bisfuranic compound with a dienophile; and to such compounds.

Preparation of phenyl compounds

The invention relates to a method for preparing a compound comprising two phenyl groups by reacting a bisfuranic compound with a dienophile; and to such compounds.

RESORCINOL-BASED COMPOUNDS AND USES THEREOF

The disclosure provides for resorcinol-based compounds, pharmaceutical compositions made therefrom, and methods of treatment thereof for various disorders, including neoplastic disorders.

Biphenyl derivative and uses thereof

The present invention relates to a biphenyl derivative and use thereof, and the biphenyl derivative has a structure represented by the formula (I) as defined in the specification. The use refers the use of the biphenyl derivative or a pharmaceutically acceptable salt or solvate thereof, or a pharmaceutical composition comprising the biphenyl derivative or a pharmaceutically acceptable salt or solvate thereof in the preparation of a medicament for the treatment and/or prevention of ischemic stroke.