Patent classifications
C07C233/91
Prodrugs of Fumarates and Their Use in Treating Various Diseases
The present invention provides compounds of formula (I), and pharmaceutical compositions thereof.
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Prodrugs of Fumarates and Their Use in Treating Various Diseases
The present invention provides compounds of formula (I), and pharmaceutical compositions thereof.
##STR00001##
Enamide process
A convenient method for converting oximes into enamides is disclosed. The process produces enamides without the concomitant production of a large volume of metallic waste. ##STR00001## The enamides are useful precursors to amides and amines.
Enamide process
A convenient method for converting oximes into enamides is disclosed. The process produces enamides without the concomitant production of a large volume of metallic waste. ##STR00001## The enamides are useful precursors to amides and amines.
Prodrugs of fumarates and their use in treating various diseases
The present invention provides compounds of formula (I), and pharmaceutical compositions thereof. ##STR00001##
Prodrugs of fumarates and their use in treating various diseases
The present invention provides compounds of formula (I), and pharmaceutical compositions thereof. ##STR00001##
ACTINIC RAY-SENSITIVE OR RADIATION-SENSITIVE RESIN COMPOSITION, RESIST FILM, PATTERN FORMING METHOD, AND METHOD FOR MANUFACTURING ELECTRONIC DEVICE
Provided is an actinic ray-sensitive or radiation-sensitive resin composition that can provide a pattern having good cross-sectional rectangularity. The actinic ray-sensitive or radiation-sensitive resin composition includes: a resin having a group that is decomposed by the action of an acid to generate a polar group; an onium salt (I) that generates an acid represented by formula (1) upon irradiation with actinic rays or radiation; and an onium salt (II) having at least one structural moiety W that includes an anionic moiety A and a cationic moiety M and forms an acidic moiety represented by HA upon irradiation with the actinic rays or radiation. The acid dissociation constant derived from the acidic moiety represented by HA and formed by replacing the cationic moiety in the structural moiety W with H.sup.+ is larger than the acid dissociation constant of the acid represented by formula (1).
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PRODRUGS OF FUMARATES AND THEIR USE IN TREATING VARIOUS DISEASES
The present invention provides compounds of formula (I), and pharmaceutical compositions thereof.
##STR00001##
PRODRUGS OF FUMARATES AND THEIR USE IN TREATING VARIOUS DISEASES
The present invention provides compounds of formula (I), and pharmaceutical compositions thereof.
##STR00001##
NAPHTHOQUINONES, PRO-DRUGS, AND METHODS OF USE THEREOF
Provided herein are naphthoquinones compounds such as those with a hydrogen bond donating group of the formula (I): wherein: R.sub.1, R.sub.2, R.sub.3, R.sub.4, R.sub.5, and n are as defined herein. Also provided herein are pharmaceutical composition of the present compounds and methods of treatment using the compounds including their use in the treatment of cancer.
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