C07C251/86

USE OF SMALL MOLECULE INHIBITORS TO KLF10 FOR MODULATION OF T REGULATORY CELLS AND CANCER IMMUNOTHERAPY

The invention relates to compositions and methods for inhibiting Krüppel-like Factor 10 (KLF10) for modulation of T regulatory cells and cancer immunotherapy.

USE OF SMALL MOLECULE INHIBITORS TO KLF10 FOR MODULATION OF T REGULATORY CELLS AND CANCER IMMUNOTHERAPY

The invention relates to compositions and methods for inhibiting Krüppel-like Factor 10 (KLF10) for modulation of T regulatory cells and cancer immunotherapy.

Organ preconditioning formulation with mitochondrial elongating agents

Provided herein is a formulation to pre-treat an organ prior to transplantation and for inducing mitochondrial morphological alterations.

Organ preconditioning formulation with mitochondrial elongating agents

Provided herein is a formulation to pre-treat an organ prior to transplantation and for inducing mitochondrial morphological alterations.

ADDITIVE FOR MEDIUM FOR PROMOTING PRODUCTION OF PARACRINE FACTOR

The present invention provides a medium additive for promoting production of a paracrine factor in a cell, containing a compound represented by the following formula (I) or a salt thereof:

##STR00001##

wherein each symbol is as defined in the DESCRIPTION.

ADDITIVE FOR MEDIUM FOR PROMOTING PRODUCTION OF PARACRINE FACTOR

The present invention provides a medium additive for promoting production of a paracrine factor in a cell, containing a compound represented by the following formula (I) or a salt thereof:

##STR00001##

wherein each symbol is as defined in the DESCRIPTION.

Analogs of Nitrofuran Antibiotics to Combat Resistance
20220009914 · 2022-01-13 ·

Novel compounds and methods of killing or inhibiting the growth of bacteria.

Analogs of Nitrofuran Antibiotics to Combat Resistance
20220009914 · 2022-01-13 ·

Novel compounds and methods of killing or inhibiting the growth of bacteria.

PARG INHIBITORS AND METHOD OF USE THEREOF

Provided herein are, inter alia, compounds inhibiting poly(ADP-ribose) Glycohydrolase (PARG) in a cancer cell and methods of treating cancer using compounds of the invention.

PARG INHIBITORS AND METHOD OF USE THEREOF

Provided herein are, inter alia, compounds inhibiting poly(ADP-ribose) Glycohydrolase (PARG) in a cancer cell and methods of treating cancer using compounds of the invention.