A high-molecular-weight compound having a plurality of polymer chains linked through a divalent or higher-valent linking group, in which the divalent or higher-valent linking group has a thiol group and at least one of a thioether structure and a thiourethane structure, and a ratio of an absolute weight-average molecular weight to a relative weight-average molecular weight (absolute Mw/relative Mw) of the high-molecular-weight compound is 1.25 or more; and a method for producing the same are provided.

A high-molecular-weight compound having a plurality of polymer chains linked through a divalent or higher-valent linking group, in which the divalent or higher-valent linking group has a thiol group and at least one of a thioether structure and a thiourethane structure, and a ratio of an absolute weight-average molecular weight to a relative weight-average molecular weight (absolute Mw/relative Mw) of the high-molecular-weight compound is 1.25 or more; and a method for producing the same are provided.

The exemplary arrangements relate to ammonium salts of partially fluorinated organic acids. The exemplary arrangements also relate to methods of synthesis of the ammonium salts of partially fluorinated organic acids. The exemplary arrangements also relate to methods of use of the ammonium salts of partially fluorinated organic acids to produce stabilizing emulsions of the oil-in-water and/or water-in-oil type. The exemplary arrangements also relate to methods of use and applications of the ammonium salts of partially fluorinated organic acids, for example use as stabilizing agents in blood substitute preparations.

A process synthesizes a compound with at least one alkylene group and at least one thiol or thiolate group. The process involves reacting a compound with at least one five-membered cyclic monothiocarbonate group with a starter selected from a compound with at least one thiol group, from a compound with at least one hydroxy group, or from a basic inorganic composed; to obtain a compound with at least one alkylene group and at least one thiol or thiolate group and carbon dioxide.

A process synthesizes a compound with at least one alkylene group and at least one thiol or thiolate group. The process involves reacting a compound with at least one five-membered cyclic monothiocarbonate group with a starter selected from a compound with at least one thiol group, from a compound with at least one hydroxy group, or from a basic inorganic composed; to obtain a compound with at least one alkylene group and at least one thiol or thiolate group and carbon dioxide.

The present invention relates to TLR2 agonist compounds and their compositions, and the use of such compounds and compositions in the prevention and/or treatment of respiratory infections, or diseases or conditions associated with viral or bacterial infections.

The present application provides processes for synthesizing lipids of Formula I useful in the synthesis of fat-soluble compounds for targeting and enhancing activity of therapeutic molecules, including siRNA.

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The present application provides processes for synthesizing lipids of Formula I useful in the synthesis of fat-soluble compounds for targeting and enhancing activity of therapeutic molecules, including siRNA.

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A method for preparing a compound of formula RSH where R represents an alkyl group, by gas-phase catalytic reaction of hydrogen sulfide with a compound of formula ROH, in the presence of a solid catalyst, according to which method the reaction is performed in the presence of a catalyst which includes one or several pure or mixed rare-earth oxide(s), one or several pure or mixed rare-earth sulfide(s), or one or several pure or mixed rare-earth oxysulfide(s). When the rare earth is lanthanum, the catalyst is a mixed oxide of lanthanum and of at least one metal selected from rare earths or not and when the rare earth is cerium, the catalyst is supported on an alumina.

A method for preparing a compound of formula RSH where R represents an alkyl group, by gas-phase catalytic reaction of hydrogen sulfide with a compound of formula ROH, in the presence of a solid catalyst, according to which method the reaction is performed in the presence of a catalyst which includes one or several pure or mixed rare-earth oxide(s), one or several pure or mixed rare-earth sulfide(s), or one or several pure or mixed rare-earth oxysulfide(s). When the rare earth is lanthanum, the catalyst is a mixed oxide of lanthanum and of at least one metal selected from rare earths or not and when the rare earth is cerium, the catalyst is supported on an alumina.