Patent classifications
C07D263/54
AROMATIC BRIDGED RING AMIDE DERIVATIVES FOR THE TREATMENT AND PROPHYLAXIS OF HEPATITIS B VIRUS INFECTION
The present invention provides novel compounds having the general formula:
##STR00001## wherein A.sub.1 to A.sub.4, X.sub.1, X.sub.2 and R.sup.1 are as described herein, compositions including the compounds and methods of using the compounds.
AROMATIC BRIDGED RING AMIDE DERIVATIVES FOR THE TREATMENT AND PROPHYLAXIS OF HEPATITIS B VIRUS INFECTION
The present invention provides novel compounds having the general formula:
##STR00001## wherein A.sub.1 to A.sub.4, X.sub.1, X.sub.2 and R.sup.1 are as described herein, compositions including the compounds and methods of using the compounds.
PESTICIDALLY ACTIVE HETEROCYCLIC DERIVATIVES WITH SULFOXIMINE CONTAINING SUBSTITUENTS
Compounds of the formula (I), wherein the substituents are as defined in claim 1. Furthermore, the present invention relates to agrochemical compositions which comprise compounds of formula (I), to preparation of these compositions, and to the use of the compounds or compositions in agriculture or horticulture for combating, preventing or controlling animal pests, including arthropods and in particular insects, nematodes, molluscs or representatives of the order Acarina.
##STR00001##
PESTICIDALLY ACTIVE HETEROCYCLIC DERIVATIVES WITH SULFOXIMINE CONTAINING SUBSTITUENTS
Compounds of the formula (I), wherein the substituents are as defined in claim 1. Furthermore, the present invention relates to agrochemical compositions which comprise compounds of formula (I), to preparation of these compositions, and to the use of the compounds or compositions in agriculture or horticulture for combating, preventing or controlling animal pests, including arthropods and in particular insects, nematodes, molluscs or representatives of the order Acarina.
##STR00001##
METHOD OF CONTROLLING SOYBEAN RUST FUNGUS HAVING RESISTANCE TO QoI FUNGICIDE
A method for controlling a soybean rust fungus having an amino acid substitution of F129L in a mitochondrial cytochrome b protein. A compound of formula (I) can be used for controlling a soybean rust fungus having an amino acid substitution of F129L in a mitochondrial cytochrome b protein,
##STR00001##
wherein: R.sup.1 represents a C1-C4 alkyl group or the like; n represents 0, 1, or 2; Q represents the group of Q1 or the like;
##STR00002##
represents the binding site to the rest of molecule; X.sup.1 represents —C(H)═ or the like; X.sup.2 represents -C(O)OCH.sub.3 or the like; J represents the group represented by J1 or the like;
##STR00003##
# represents the binding position to E; Y.sup.1 represents an oxygen atom or the like; Y.sup.2 represents ═C(R.sup.6)— or the like; R.sup.6 represents a C1-C4 alkyl group or the like; and E represents a C1-C6 chain hydrocarbon group or the like.
USE OF NON-STEROIDAL ANTI-INFLAMMATORY COMPOUNDS FOR TREATMENT OF INFLAMMATION
The present disclosure provides use of non-steroidal anti-inflammatory compositions as described herein for used in the treatment of inflammation, inflammatory-related diseases, pain and/or fever.
FLUORESCENT PROBE, PREPARATION METHOD THEREFOR AND USE THEREOF
Provided are a fluorescent probe, a preparation method therefor and a use thereof. The fluorescent probe responds to viscosity sensitively and specifically, can be used for the specific fluorescence labeling of proteins and can also be used in the quantification, detection or kinetic study of proteins and the imaging of cells, tissues and living bodies.
FLUORESCENT PROBE, PREPARATION METHOD THEREFOR AND USE THEREOF
Provided are a fluorescent probe, a preparation method therefor and a use thereof. The fluorescent probe responds to viscosity sensitively and specifically, can be used for the specific fluorescence labeling of proteins and can also be used in the quantification, detection or kinetic study of proteins and the imaging of cells, tissues and living bodies.
NADPH OXIDASE 4 INHIBITORS
The invention relates to 2,5-disubstituted benzoxazole and benzothiazole derivatives of Formula (I)
##STR00001##
wherein L, X, Y, and ring (A) are as described in the description, their preparation and their use as pharmaceutically active compounds. Said compounds may be useful for the prevention or treatment of diseases or disorders associated with impaired reactive oxygen species (ROS) production, and/or for the prevention or treatment of various fibrotic diseases.
NADPH OXIDASE 4 INHIBITORS
The invention relates to 2,5-disubstituted benzoxazole and benzothiazole derivatives of Formula (I)
##STR00001##
wherein L, X, Y, and ring (A) are as described in the description, their preparation and their use as pharmaceutically active compounds. Said compounds may be useful for the prevention or treatment of diseases or disorders associated with impaired reactive oxygen species (ROS) production, and/or for the prevention or treatment of various fibrotic diseases.