The invention provides novel compounds having the general formula (I) and pharmaceutically acceptable salts thereof, wherein the variables RA, subscript n, ring A, X.sup.2, L, subscript m, X.sup.1, ring D, R.sup.1, and R.sup.N have the meaning as described herein, and compositions containing such compounds and methods for using such compounds and compositions. ##STR00001##

The present invention relates to a new compound of formula (I) wherein the variables have the meaning as indicated in the claims; or an enantiomer or salt thereof. The compounds of formula (I) are useful in the control of parasites, in particular endoparasites, in and on vertebrates. ##STR00001##

The present disclosure provides an organic compound, a light extraction layer material, and an organic electronic device. The organic compound has a structure represented by formula (1). X.sub.1 and X.sub.2 are independently selected from O, S, or NR.sub.1; L.sub.1 and L.sub.2 are independently selected from a single bond, a substituted or unsubstituted aromatic group having 6 to 30 ring atoms, or a substituted or unsubstituted heteroaromatic group having 5 to 30 ring atoms; M.sub.1 and M.sub.2 are independently selected from a substituted or unsubstituted aromatic group having 6 to 60 ring atoms, a substituted or unsubstituted heteroaromatic group having 5 to 60 ring atoms, or a substituted or unsubstituted amino group.

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The invention relates to 2,5-disubstituted benzoxazole and benzothiazole derivatives of Formula (I)

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wherein L, X, Y, and ring (A) are as described in the description, their preparation and their use as pharmaceutically active compounds. Said compounds may be useful for the prevention or treatment of diseases or disorders associated with impaired reactive oxygen species (ROS) production, and/or for the prevention or treatment of various fibrotic diseases.

Provided herein are compounds of Formula (I), and pharmaceutically acceptable salts, N-oxides, or solvates thereof,

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Also provided herein are pharmaceutical compositions, comprising compounds of Formula (I), and methods of using compounds of Formula (I).

Provided herein are compounds of Formula (I), and pharmaceutically acceptable salts, N-oxides, or solvates thereof,

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Also provided herein are pharmaceutical compositions, comprising compounds of Formula (I), and methods of using compounds of Formula (I).

The present invention relates to the following compounds for use in the treatment of a bacterial infection ##STR00001##
wherein the integers are as defined in the description. The invention also relates to compounds for use as medicaments, pharmaceutical compositions and some novel compounds.

Disclosed are compound of formula (I) and pharmaceutically accepted salts and prodrugs thereof, wherein each of R.sup.1, R.sup.2, R.sup.3, R.sup.4, R.sup.5, R.sup.6, X.sup.1, and X.sup.2 is as defined in the description. These compounds are protein kinases inhibitors, especially the inhibitors of Mek, which are useful in the treatment of cancers and inflammation of mammals. Disclosed are the treatment methods of cancers and inflammation of mammals as well as pharmaceutical expositions comprising the compounds described herein. The preparation of benzoheterocyclic compounds are disclosed. Disclosed are the preparation of potential drug candidates, such as benzooxazol, benzothiazol, benzothiadiazol and the like. ##STR00001##

Disclosed are compound of formula (I) and pharmaceutically accepted salts and prodrugs thereof, wherein each of R.sup.1, R.sup.2, R.sup.3, R.sup.4, R.sup.5, R.sup.6, X.sup.1, and X.sup.2 is as defined in the description. These compounds are protein kinases inhibitors, especially the inhibitors of Mek, which are useful in the treatment of cancers and inflammation of mammals. Disclosed are the treatment methods of cancers and inflammation of mammals as well as pharmaceutical expositions comprising the compounds described herein. The preparation of benzoheterocyclic compounds are disclosed. Disclosed are the preparation of potential drug candidates, such as benzooxazol, benzothiazol, benzothiadiazol and the like. ##STR00001##

A compound represented by a formula (IIa) is provided. In formula (IIa), Y.sup.1 to Y.sup.8 represent O, S, OC(O), C(O)O or the like, G.sup.1 and G.sup.2 represent a divalent linear aliphatic group having 1 to 20 carbon atoms or the like, Z.sup.1 and Z.sup.2 represent an alkenyl group having 2 to 10 carbon atoms or the like, A.sup.x represents a group represented by a formula (II), wherein X represents an oxygen atom, a sulfur atom or the like, D represents an alkylene group having 1 to 20 carbon atoms or the like, A.sup.1 represents a trivalent aromatic group or the like, A.sup.2 and A.sup.3 represent a divalent alicyclic hydrocarbon group having 3 to 30 carbon atoms or the like, A.sup.4 and A.sup.5 represent a divalent aromatic group having 4 to 30 carbon atoms or the like, Q.sup.1 represents an alkyl group having 1 to 6 carbon atoms or the like, and m and n are 0 or 1.

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