Compounds of formula III:

##STR00001##

and salts thereof are disclosed. Also disclosed are methods for preparing compounds of formula III, intermediates useful for preparing compounds of formula III and methods for preparing compounds and materials from compounds of formula III.

In certain aspects, the invention relates to methods of treating proliferative cervical disorders (such as cervical cancer and cervical dysplasia) and treating virus infection by administering artemisinin-related compounds. In certain aspects, the invention relates to methods of treating a tumor induced by an oncogenic virus, methods of killing or inhibiting a squamous cell carcinoma, and methods of inhibiting the replication of a virus, by administering artemisinin-related compounds.

In certain aspects, the invention relates to methods of treating proliferative cervical disorders (such as cervical cancer and cervical dysplasia) and treating virus infection by administering artemisinin-related compounds. In certain aspects, the invention relates to methods of treating a tumor induced by an oncogenic virus, methods of killing or inhibiting a squamous cell carcinoma, and methods of inhibiting the replication of a virus, by administering artemisinin-related compounds.

The present disclosure relates to concise processes for making (−)-picrotoxinin (1, PXN) and 5-methyl-picrotoxinin (20, 5MePXN), and to 5MePXN, its pharmaceutical compositions, and its method of use for inhibiting GABA.sub.A receptor.

The present invention relates to stereochemically defined polypropionates and methods for preparing and using the same. The stereochemically defined polypropionates may be useful in the synthesis of natural products and/or natural product-like libraries.

A polymer for resist use is obtainable from a hemiacetal compound having formula (1a) wherein R.sup.1 is H, CH.sub.3 or CF.sub.3, R.sup.2 to R.sup.4 each are H or a monovalent hydrocarbon group, X.sup.1 is a divalent hydrocarbon group, ZZ designates a non-aromatic mono- or polycyclic ring of 4 to 20 carbon atoms having a hemiacetal structure, k.sup.1=0 or 1, and k.sup.2=0 to 3. A resist composition comprising the polymer displays controlled acid diffusion and low roughness during both positive and negative tone developments. ##STR00001##

A polymer for resist use is obtainable from a hemiacetal compound having formula (1a) wherein R.sup.1 is H, CH.sub.3 or CF.sub.3, R.sup.2 to R.sup.4 each are H or a monovalent hydrocarbon group, X.sup.1 is a divalent hydrocarbon group, ZZ designates a non-aromatic mono- or polycyclic ring of 4 to 20 carbon atoms having a hemiacetal structure, k.sup.1=0 or 1, and k.sup.2=0 to 3. A resist composition comprising the polymer displays controlled acid diffusion and low roughness during both positive and negative tone developments. ##STR00001##

The present invention relates to novel phenylaminopyrimidine(FAP)-derived compounds of general formulas I and II:

##STR00001##

Where, in formula I, R.sub.1 is:

##STR00002##

Where, in formula II, X.sup.+ is selected among one of the compounds below:

##STR00003##

Where, in formula II, Y is

##STR00004##

The compounds of the present invention are powerful and nonspecific tyrosine kinase inhibitors, and the use of these compounds in the treatment.

The present invention relates to novel phenylaminopyrimidine(FAP)-derived compounds of general formulas I and II:

##STR00001##

Where, in formula I, R.sub.1 is:

##STR00002##

Where, in formula II, X.sup.+ is selected among one of the compounds below:

##STR00003##

Where, in formula II, Y is

##STR00004##

The compounds of the present invention are powerful and nonspecific tyrosine kinase inhibitors, and the use of these compounds in the treatment.

Certain embodiments are directed to oridonin analogs or derivatives. In certain aspects, the derivatives are used as anticancer or anti-inflammatory agents.