Patent classifications
C07D493/20
PROCESS FOR SEPARATING AND PURIFYING ARTEMISININ
The present invention belongs to a process for separating and purifying artemisinin comprising S1. concentrating and pressure filtering an artemisinin extraction liquid to obtain a crude artemisinin crystal 1 and a mother liquor 1, and concentrating the mother liquor 1 to obtain an artemisinin extract 1; S2. adding the artemisinin extract 1 to an aqueous alcohol solution to obtain an aqueous alcohol extraction liquid 1 and an artemisinin extract 2; S3. subjecting the artemisinin extract 2 to S2 so as to obtain an aqueous alcohol extraction liquid 2 and an artemisinin extract 3; S4. combining the aqueous alcohol extraction liquids 1 and 2 to obtain a crude artemisinin crystal 2 and a mother liquor 2; and S5. combining the crude artemisinin crystals 1 and 2, then dissolving same in an alcohol solvent and filtering same, heating the filtrate and then concentrating same to obtain a fine artemisinin product.
Compounds and method of preventing or treating cancer using the same
The present disclosure relates to novel compounds and a method of preventing or treating cancer using the same, and more particularly to compounds having structural formulae 1 to 3. The compounds of the present disclosure exhibit an excellent activity of inhibiting various cancer cells, and thus can be effectively used in a composition or method for preventing, alleviating, or treating cancer.
Compounds and method of preventing or treating cancer using the same
The present disclosure relates to novel compounds and a method of preventing or treating cancer using the same, and more particularly to compounds having structural formulae 1 to 3. The compounds of the present disclosure exhibit an excellent activity of inhibiting various cancer cells, and thus can be effectively used in a composition or method for preventing, alleviating, or treating cancer.
CONTROLLED RELEASE FORMULATIONS FOR THE TREATMENT OF MALARIA
The present disclosure relates to a controlled release complex of a carboxylated polymer having carboxyl groups having a degree of substitution of about 0.1 to about 1.0, forming a complex through ionic interaction with an antimalarial alkaloid extract; a solid oral dosage form comprising the same, and a solid oral dosage form comprising an antimalarial drug combination which comprises the controlled release complex of the present invention and an antimalarial drug.
VERRUCARIN A DERIVATIVES AND ANTIBODY DRUG CONJUGATES THEREOF
Provided herein are verrucarin A derivatives, linker-verrucarin A derivatives and antibody drug conjugates thereof. In one embodiment, the verrucarin A derivatives, linker-verrucarin A derivatives and antibody drug conjugates are useful in treating viral diseases.
VERRUCARIN A DERIVATIVES AND ANTIBODY DRUG CONJUGATES THEREOF
Provided herein are verrucarin A derivatives, linker-verrucarin A derivatives and antibody drug conjugates thereof. In one embodiment, the verrucarin A derivatives, linker-verrucarin A derivatives and antibody drug conjugates are useful in treating viral diseases.
Materials for organic electroluminescent devices
The present invention relates to compounds of the formula (1) which are suitable for use in electronic devices, in particular organic electroluminescent devices, and to electronic devices which comprise these compounds.
Composition, method of manufacture, and use of site-specific delivery of bruceolides for treatment of cancer and other diseases
Disclosed are bruceolides for the treatment of cancer, and other diseases, selectively targeting unwanted cells. The disclosed bruceolides may include a site specific cleavable moiety inhibiting the chemotoxic activity until cleaved, i.e., removed, within and/or near a cancer to be treated. As to facilitate selective delivery to cancer tumors, the disclosed bruceolides may be loaded into, attached to or otherwise carried by nanoparticles.
Composition, method of manufacture, and use of site-specific delivery of bruceolides for treatment of cancer and other diseases
Disclosed are bruceolides for the treatment of cancer, and other diseases, selectively targeting unwanted cells. The disclosed bruceolides may include a site specific cleavable moiety inhibiting the chemotoxic activity until cleaved, i.e., removed, within and/or near a cancer to be treated. As to facilitate selective delivery to cancer tumors, the disclosed bruceolides may be loaded into, attached to or otherwise carried by nanoparticles.
Organic heterocyclic compound and light-emitting diode comprising same
The present disclosure relates to an organic compound represented by Chemical Formula A or B, and an organic light-emitting diode comprising the same.