Patent classifications
C07D495/16
ORGANIC COMPOUND AND ORGANIC LIGHT EMITTING ELEMENT COMPRISING THE SAME
The present disclosure provides an organic compound represented by the Chemical Formula 1 and an organic light emitting element including the same. Specifically, there may be provided an organic light emitting element having high efficiency or long lifespan by including a first electrode, a second electrode, and an organic material layer positioned therebetween, where the organic material layer includes an organic compound represented by the Chemical Formula 1.
ORGANIC COMPOUND AND ORGANIC LIGHT EMITTING ELEMENT COMPRISING THE SAME
The present disclosure provides an organic compound represented by the Chemical Formula 1 and an organic light emitting element including the same. Specifically, there may be provided an organic light emitting element having high efficiency or long lifespan by including a first electrode, a second electrode, and an organic material layer positioned therebetween, where the organic material layer includes an organic compound represented by the Chemical Formula 1.
INHIBITORS OF BRUTON'S TYROSINE KINASE AND METHOD OF THEIR USE
The present disclosure is directed to compounds of Formula (I) and methods of their use and preparation, as well as compositions comprising compounds of Formula (I).
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INHIBITORS OF BRUTON'S TYROSINE KINASE AND METHOD OF THEIR USE
The present disclosure is directed to compounds of Formula (I) and methods of their use and preparation, as well as compositions comprising compounds of Formula (I).
##STR00001##
INHIBITORS OF BRUTON'S TYROSINE KINASE AND METHOD OF THEIR USE
- Nidhi Arora ,
- Genesis M. Bacani ,
- Joseph Kent BARBAY ,
- Scott D. Bembenek ,
- Min Cai ,
- Wei Chen ,
- Charlotte Pooley Deckhut ,
- James P. Edwards ,
- Brahmananda Ghosh ,
- Baoyu Hao ,
- Kevin D. KREUTTER ,
- Gang Li ,
- Mark S. Tichenor ,
- Jennifer D. VENABLE ,
- Jianmei Wei ,
- John J.M. WIENER ,
- Yao Wu ,
- Yaoping Zhu ,
- Feihuang Zhang ,
- Zheng Zhang ,
- Kun Xiao
The present disclosure is directed to compounds of formula I′ and methods of their use and preparation, as well as compositions comprising compounds of formula I′.
##STR00001##
INHIBITORS OF BRUTON'S TYROSINE KINASE AND METHOD OF THEIR USE
- Nidhi Arora ,
- Genesis M. Bacani ,
- Joseph Kent BARBAY ,
- Scott D. Bembenek ,
- Min Cai ,
- Wei Chen ,
- Charlotte Pooley Deckhut ,
- James P. Edwards ,
- Brahmananda Ghosh ,
- Baoyu Hao ,
- Kevin D. KREUTTER ,
- Gang Li ,
- Mark S. Tichenor ,
- Jennifer D. VENABLE ,
- Jianmei Wei ,
- John J.M. WIENER ,
- Yao Wu ,
- Yaoping Zhu ,
- Feihuang Zhang ,
- Zheng Zhang ,
- Kun Xiao
The present disclosure is directed to compounds of formula I′ and methods of their use and preparation, as well as compositions comprising compounds of formula I′.
##STR00001##
COMPOSITIONS COMPRISING THIENOPYRIMIDINE AND THIENOPYRIDINE COMPOUNDS AND METHODS OF USE THEREOF
The present disclosure relates generally to thienopyrimidine and thienopyridine compounds and methods of use thereof. In particular embodiments, the present disclosure provides compositions comprising thienopyrimidine and thienopyridine compounds of Formula 3:
##STR00001##
and methods of use to inhibit the interaction of menin with MLL1, MLL2 and MLL-fusion oncoproteins.
COMPOSITIONS COMPRISING THIENOPYRIMIDINE AND THIENOPYRIDINE COMPOUNDS AND METHODS OF USE THEREOF
The present disclosure relates generally to thienopyrimidine and thienopyridine compounds and methods of use thereof. In particular embodiments, the present disclosure provides compositions comprising thienopyrimidine and thienopyridine compounds of Formula 3:
##STR00001##
and methods of use to inhibit the interaction of menin with MLL1, MLL2 and MLL-fusion oncoproteins.
ORGANIC ELECTROLUMINESCENT COMPOUND AND ORGANIC ELECTROLUMINESCENT DEVICE COMPRISING THE SAME
The present disclosure relates to an organic electroluminescent compound represented by formula 1 and an organic electroluminescent device comprising the same. By comprising the organic electroluminescent compound of the present disclosure, it is possible to provide an organic electroluminescent device having improved operating voltage, luminous efficiency, lifetime, and/or power efficiency.
Inhibitors of Bruton's tyrosine kinase and methods of their use
The present disclosure is directed to compounds of Formula (I) and methods of their use and preparation, as well as compositions comprising compounds of Formula (I). ##STR00001##