Patent classifications
C07D513/20
Spirooxindole-copper complex as novel efficient anticorrosion agent for C-steel
New spirooxindole compounds are described herein, as well as the use of such spirooxindole compounds in forming copper complexes that act as efficient anticorrosion agents for C-steel. Also described are methods for forming the new spirooxindole compounds as well as anti-corrosion coatings containing the spirooxindole-copper complexes, CuL.
Spirooxindole-copper complex as novel efficient anticorrosion agent for C-steel
New spirooxindole compounds are described herein, as well as the use of such spirooxindole compounds in forming copper complexes that act as efficient anticorrosion agents for C-steel. Also described are methods for forming the new spirooxindole compounds as well as anti-corrosion coatings containing the spirooxindole-copper complexes, CuL.
Spiro-sulfonamide derivatives as inhibitors of myeloid cell leukemia-1 (MCL-1) protein
The disclosure is directed to compounds of Formula I ##STR00001##
Pharmaceutical compositions comprising compounds of Formula I as well as methods of their use and preparation, are also described.
Spiro-sulfonamide derivatives as inhibitors of myeloid cell leukemia-1 (MCL-1) protein
The disclosure is directed to compounds of Formula I ##STR00001##
Pharmaceutical compositions comprising compounds of Formula I as well as methods of their use and preparation, are also described.
CYCLIZED SULFAMOYLARYLAMIDE DERIVATIVES AND THE USE THEREOF AS MEDICAMENTS FOR THE TREATMENT OF HEPATITIS B
Inhibitors of HBV replication of Formula (I-A)
##STR00001##
including stereochemically isomeric forms, and salts, hydrates, solvates thereof, wherein R.sup.a to R.sup.d, and R.sup.1 to R.sup.8 have the meaning as defined herein.
The present invention also relates to processes for preparing said compounds, pharmaceutical compositions containing them and their use, alone or in combination with other HBV inhibitors, in HBV therapy.
CYCLIZED SULFAMOYLARYLAMIDE DERIVATIVES AND THE USE THEREOF AS MEDICAMENTS FOR THE TREATMENT OF HEPATITIS B
Inhibitors of HBV replication of Formula (I-A)
##STR00001##
including stereochemically isomeric forms, and salts, hydrates, solvates thereof, wherein R.sup.a to R.sup.d, and R.sup.1 to R.sup.8 have the meaning as defined herein.
The present invention also relates to processes for preparing said compounds, pharmaceutical compositions containing them and their use, alone or in combination with other HBV inhibitors, in HBV therapy.
MCL1 INHIBITORS
The present disclosure generally relates to compounds of Formula (I) and pharmaceutical compositions that may be used in methods of treating cancer.
##STR00001##
MCL1 INHIBITORS
The present disclosure generally relates to compounds of Formula (I) and pharmaceutical compositions that may be used in methods of treating cancer.
##STR00001##
Tricyclic pyridones and pyrimidones
Compounds with KRAS G12C inhibitory active are disclosed and methods of using the same to treat a cancer comprising a K-Ras G12C mutation.
Tricyclic pyridones and pyrimidones
Compounds with KRAS G12C inhibitory active are disclosed and methods of using the same to treat a cancer comprising a K-Ras G12C mutation.