A process comprising: (a) contacting a feed stream comprising a di-alkyltin dihalide distillate with an alkylation agent, thereby forming an alkylated mixture comprising R.sub.4Sn and optionally R.sub.3SnX, R.sub.2SnX.sub.2, or mixtures thereof, where R is a linear, branched or cyclic C.sub.1-C.sub.20 alkyl, and X is a halide; (b) contacting the alkylated mixture with SnX.sub.4, thereby forming an alkyltin halide mixture comprising RSnX.sub.3, R.sub.2SnX.sub.2, and optionally impurities, R.sub.3SnX or mixtures thereof; (c) separating by distillation the alkyltin halide mixture to form a mono-alkyltin halide-rich distillate stream and a liquid di-alkyltin halide-rich bottoms stream comprising R.sub.2SnX.sub.2, RSnX.sub.3, and optionally impurities, R.sub.3SnX, or mixtures thereof; (d) separating by distillation the di-alkyltin halide-rich bottoms stream, thereby forming the liquid di-alkyltin dihalide distillate comprising R.sub.2SnX.sub.2, and optionally RSnX.sub.3, R.sub.3SnX or mixtures thereof, and an impurities-rich bottoms stream; and (e) recycling a part, x.sub.recycle, of the liquid di-alkyltin dihalide distillate to step (a), where x.sub.recycle ranges from greater than 0.0% to 100.0% of the distillate.

Provided herein are methods of making metal halide perovskites, including methods of making bulk crystals or micro crystals. The metal halide perovskites may be a light emitting material.

A Pb-free Sn-halide Perovskite solar cell with improved photoelectric conversion efficiency is provided. A solar cell uses a perovskite compound represented by ABX.sub.3 where A is a cation, B is a metal, and X is a halogen, wherein each of A, B and X may be composed of a plurality of elements, and B includes Sn and Ge.

The present invention disclosed a novel (4,8-bis(5-(trimethylstannyl)thiophen-2-yl)benzo[1,2-b:4,5-b]dithiophene-2,6-diyl)bis(trimethylstannane) compound, its preparation and use for the synthesis of polymers, which is used to build devices for capacitor and solar applications. The present invention further discloses to an improved process for the synthesis of DTBDT having improved yields.

The present invention provides methods for radiolabeling compounds useful as Hsp90 inhibitors. The present invention also provides intermediates useful in such methods, and compositions of radiolabeled compounds. The present invention provides, among other things novel methods for the synthesis of radiolabeled compounds. In certain embodiments, the present invention provides compounds of formula I.

Described herein are complexes comprising a cationic antibacterial agent and a metal salt; oral care compositions comprising same; along with methods of making and using these complexes and compositions.

Prostate-specific membrane antigen (PSMA) binding compounds having radioisotope substituents are described, as well as chemical precursors thereof. Compounds include pyridine containing compounds, compounds having phenylhydrazine structures, and acylated lysine compounds. The compounds allow ready incorporation of radionuclides for single photon emission computed tomography (SPECT) and positron emission tomography (PET) for imaging, for example, prostate cancer cells and angiogenesis.

A process of preparing compounds of general formula I, ##STR00001##
by cuprate coupling of a vinyl cuprate of general formula II ##STR00002##
with a protected enone of general formula IV ##STR00003##
to produce a compound of general formula (V) ##STR00004##
removing the protecting groups of the compound of general formula (V) and purifying the compound of general formula (I) by chromatography; wherein the vinyl cuprate of formula (II) is prepared by reacting a vinyl stannane of formula III with copper halide CuX and alkyllithium R1Li ##STR00005##
and wherein an excess of the alkyllithium is decomposed before the said coupling reaction.

The present technology is directed to compounds, compositions, medicaments, and methods related to the treatment of cancers expressing PSMA. The compounds are of Formulas I & II ##STR00001##
or pharmaceutically acceptable salts thereof. The present technology is especially well-suited for use in treating prostate cancer.

By providing a novel polycyclic aromatic compound in which a plurality of aromatic rings are linked via a boron atom, a nitrogen atom, or the like, options of a material for an organic EL element are increased. In addition, by using the novel polycyclic aromatic compound as a material for an organic electroluminescent element, an excellent organic EL element is provided.