Patent classifications
C07H15/04
PROCESS FOR PREPARING GLUCOPYRANOSYL-SUBSTITUTED BENZYL-BENZENE DERIVATIVES
The present invention relates to processes for preparing glucopyranosyl-substituted benzyl-benzene derivatives of general formula III,
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wherein R.sup.1, R.sup.2 and R′ are defined according to claim 1; and the use of such processes in the synthesis of SGLT2 inhibitors.
Immunogenic trehalose compounds and uses thereof
Disclosed herein are immunogenic trehalose compounds and methods of use thereof, for example as vaccine adjuvants.
Immunogenic trehalose compounds and uses thereof
Disclosed herein are immunogenic trehalose compounds and methods of use thereof, for example as vaccine adjuvants.
Novel Sugar Derivatives and Uses Thereof to Prepare Novel Senolytic Agents
Provided herein are novel sugar derivatives which are intermediates for preparing senolytic agents that selectively kill senescent cells associated with numerous pathologies and diseases, including age-related pathologies and diseases.
Modified oligonucleotides and compound that can be used for synthesizing same
The present disclosure falls within the field of biomedical technology, and in particular relates to modified oligonucleotides and a compound that can be used for synthesizing same and a method for modifying oligonucleotides. The present disclosure also relates to the use of the modified oligonucleotides for preventing and/or treating diseases associated with the liver in a subject.
Modified oligonucleotides and compound that can be used for synthesizing same
The present disclosure falls within the field of biomedical technology, and in particular relates to modified oligonucleotides and a compound that can be used for synthesizing same and a method for modifying oligonucleotides. The present disclosure also relates to the use of the modified oligonucleotides for preventing and/or treating diseases associated with the liver in a subject.
FLAVOR COMPOSITION CONTAINING HMG GLUCOSIDES
A flavor composition containing at least one HMG glucoside compound that can be used to enhance the taste of edible compositions including sweet goods, such as confectionery goods, and savory goods, such as pet foods.
FLAVOR COMPOSITION CONTAINING HMG GLUCOSIDES
A flavor composition containing at least one HMG glucoside compound that can be used to enhance the taste of edible compositions including sweet goods, such as confectionery goods, and savory goods, such as pet foods.
NEW IMMUNOSTIMULATORS AND USE THEREOF IN IMMUNOTHERAPY
The present invention relates to a new family of iNKT stimulators, referred to as 6″-O-PEGm-NHR-GalCer, which are potent analogues of KRN7000. These iNKT stimulators can advantageously be used in therapy, in particular for the prevention and/or treatment of many diseases requiring a stimulation of an immune response, such as cancer, viral, bacterial or parasitic diseases, autoimmune diseases or inflammatory diseases. The iNKT cell stimulator of the invention may be coupled to a biological carrier, such as a therapeutic and/or targeting agent, or be vectorized, for example in nanoparticles, to be specifically delivered to target cells.
NEW IMMUNOSTIMULATORS AND USE THEREOF IN IMMUNOTHERAPY
The present invention relates to a new family of iNKT stimulators, referred to as 6″-O-PEGm-NHR-GalCer, which are potent analogues of KRN7000. These iNKT stimulators can advantageously be used in therapy, in particular for the prevention and/or treatment of many diseases requiring a stimulation of an immune response, such as cancer, viral, bacterial or parasitic diseases, autoimmune diseases or inflammatory diseases. The iNKT cell stimulator of the invention may be coupled to a biological carrier, such as a therapeutic and/or targeting agent, or be vectorized, for example in nanoparticles, to be specifically delivered to target cells.