The present invention relates to the use of at least one tetra functional non-ionic amphiphilic block copolymer as a vehicle for capped or uncapped mRNA for intracellular delivery for gene therapy.

The present invention relates to the use of at least one tetra functional non-ionic amphiphilic block copolymer as a vehicle for capped or uncapped mRNA for intracellular delivery for gene therapy.

The present invention provides isolated nanosheets each of which includes a plurality of pseudo-polyrotaxanes and which are easily isolated without adhering to each other. The present invention provides an isolated nanosheet including a plurality of pseudo-polyrotaxanes each having one or more first cyclic molecules and a linear molecule included in a cavity or cavities of the first cyclic molecules in a skewered manner, wherein the linear molecules include, as part thereof, first linear molecules each having an ionizable group that ionizes in water or an aqueous solution.

According to one aspect of the present invention, an organic fluorine compound is represented by a general formula
(R-π-E-CH.sub.2).sub.2-A  (1A)
(where A is a divalent perfluoropolyether group, π is an arylene group or a single bond, R is an alkenyl group or an alkynyl group, and E is an ether bond or an ester bond or a group that is represented by a chemical formula
—O—CH.sub.2CH(OH)CH.sub.2O—
two groups each of which is represented by a general formula
R-π-E-CH.sub.2—
may be the same or different, and at least one n among two π is an arylene group).

According to one aspect of the present invention, an organic fluorine compound is represented by a general formula
(R-π-E-CH.sub.2).sub.2-A  (1A)
(where A is a divalent perfluoropolyether group, π is an arylene group or a single bond, R is an alkenyl group or an alkynyl group, and E is an ether bond or an ester bond or a group that is represented by a chemical formula
—O—CH.sub.2CH(OH)CH.sub.2O—
two groups each of which is represented by a general formula
R-π-E-CH.sub.2—
may be the same or different, and at least one n among two π is an arylene group).

Provided is a semiconductor nanoparticle complex in which a ligand is coordinated to a surface of a semiconductor nanoparticle. The semiconductor nanoparticle is a core-shell type semiconductor nanoparticle including a core containing In and P and one or more layers of shells. The semiconductor nanoparticle further includes halogen and the molar ratio of halogen to In is 0.80 to 15.00 in terms of atoms. The ligand includes one or more kinds of mercapto fatty acid esters represented by the following general formula: HS—R.sub.1—COO—R.sub.2. The mercapto fatty acid ester has an SP value of 9.20 or more. The mercapto fatty acid ester has a molecular weight of 700 or less, and the average SP value of the entire ligand is 9.10 to 11.00. The present invention provides a semiconductor nanoparticle complex dispersible at a high mass fraction in a polar dispersion medium while keeping high fluorescence quantum yield.

Provided is a semiconductor nanoparticle complex in which a ligand is coordinated to a surface of a semiconductor nanoparticle. The semiconductor nanoparticle is a core-shell type semiconductor nanoparticle including a core containing In and P and one or more layers of shells. The semiconductor nanoparticle further includes halogen and the molar ratio of halogen to In is 0.80 to 15.00 in terms of atoms. The ligand includes one or more kinds of mercapto fatty acid esters represented by the following general formula: HS—R.sub.1—COO—R.sub.2. The mercapto fatty acid ester has an SP value of 9.20 or more. The mercapto fatty acid ester has a molecular weight of 700 or less, and the average SP value of the entire ligand is 9.10 to 11.00. The present invention provides a semiconductor nanoparticle complex dispersible at a high mass fraction in a polar dispersion medium while keeping high fluorescence quantum yield.

High temperature lubricants for magnetic media are provided. One such lubricant includes fluoroalkyl, fluoroalkenyl, perfluoroalkyl, or perfluoroalkyl ether segments, anchoring functional groups engageable with a protective overcoat of a magnetic recording media, and cyclic functional groups. The lubricants can be used in conjunction with a magnetic recording medium and/or a magnetic data storage system.

The present invention relates to the use of at least one tetrafunctional non-ionic amphiphilic block copolymer as a vehicle for capped or uncapped mRNA for intracellular delivery for gene therapy.

The present invention relates to the use of at least one tetrafunctional non-ionic amphiphilic block copolymer as a vehicle for capped or uncapped mRNA for intracellular delivery for gene therapy.