A fluorine-containing ether compound represented by the following formula (1).
R.sup.1R.sup.2CH.sub.2R.sup.3CH.sub.2R.sup.4(1)
(R.sup.1 is an organic group having an alicyclic structure having 3 to 13 carbon atoms; R.sup.2 is represented by the following formula (2), and a in the formula (2) is an integer of 1 to 3; R.sup.3 is a perfluoropolyether chain; and R.sup.4 is a terminal group having two or three polar groups, in which individual polar groups bond to different carbon atoms and the carbon atoms to which the polar groups bond are bonded to each other through a linking group having a carbon atom to which the polar groups do not bond.) ##STR00001##

This disclosure provides improved lipid-based compositions, including lipid nanoparticle compositions, and methods of use thereof for delivering agents in vivo including nucleic acids and proteins. These compositions are not subject to accelerated blood clearance and they have an improved toxicity profile in vivo.

A fluoropolymer having fluoropolyether linkages, at least two ester linkages, and hydrolyzable functional groups is represented by chemical structure (I): ##STR00001##
With respect to chemical structure (I), m is a number from 1 to 4 and n is a number from 10 to 60, each R.sup.1 is independently fluorine or CF.sub.3, R.sup.2 is an alkylene group, R.sup.3 is an alkylene group in which one or more hydrogens of the alkylene group are optionally substituted with fluorine, R.sup.4 is an alkyl group in which one or more hydrogens of the alkyl group are substituted with fluorine, R.sup.5 is an alkylene group in which at least one hydrogen of the alkylene group is substituted with a group comprising CF.sub.3, CF.sub.2H, or a hydrolyzable silyl group, and Z is a group represented by chemical structure (II), ##STR00002##
Methods of preparing the fluoropolymer and coating compositions containing the fluoropolymer are also included.

To provide a fluorinated ether compound, a fluorinated ether composition and a coating liquid, capable of forming a surface layer excellent in water/oil repellency, abrasion resistance, fingerprint stain removability, lubricity, chemical resistance and light resistance, as well as an article having such a surface layer. A fluorinated ether compound represented by A.sup.1-O-Q.sup.1-(R.sup.f11O).sub.m1R.sup.f12R.sup.11N[R.sup.12SiR.sup.13.sub.n1X.sup.1.sub.3-n1].sub.2, wherein A.sup.1: C.sub.1-20 perfluoroalkyl group, Q.sup.1: single bond, fluoroalkylene group containing at least one hydrogen atom, etc., R.sup.f11, R.sup.f12: perfluoroalkylene group, m1: integer of from 2 to 200, R.sup.11: single bond, alkylene group, etc., R.sup.12: alkylene group, etc., R.sup.13: monovalent hydrocarbon group, etc., X.sup.1: hydrolyzable group, n1: integer of from 0 to 2.

To provide a hydrophilic polymer derivative having a novel linker technique which is able to from a hydrophilic polymer pro-drug of a drug containing an amino group or the like in order to overcome the restrictions of conventional hydrophilic polymer pro-drugs. A hydrophilic polymer derivative containing a hydrophilic polymer moiety and an acetal moiety, wherein the hydrophilic polymer derivative contains a structure represented by formula (1) or formula (2):

##STR00001##

Thermally-conductive gap fillers are described. The gap fillers comprise an aziridino-functional polyether polymer and thermally conductive particles. Initiators suitable for such systems e also described. Such gap fillers may be used in various applications including the manufacture of battery modules and subunits.

A polyphenylene ether bismaleimide resin is provided. The polyphenylene ether bismaleimide resin (PPE-BMI) is formed from a modified polyphenylene ether diamine and a maleic anhydride by a condensation polymerization. The modified polyphenylene ether diamine is formed by reacting a phenol-based compound with a polyphenylene ether.

A vinyl-containing copolymer is copolymerized from (a) first compound, (b) second compound, and (c) third compound. (a) First compound is an aromatic compound having a single vinyl group. (b) Second compound is polybutadiene or polybutadiene-styrene having side vinyl groups. (c) Third compound is an acrylate compound. The vinyl-containing copolymer includes 0.003 mol/g to 0.010 mol/g of benzene ring, 0.0005 mol/g to 0.008 mol/g of vinyl group, and 1.2*10.sup.?5 mol/g to 2.4*10.sup.?4 mol/g of ester group.

An object to provide a lubricant that makes it possible, in a magnetic disk device in which energy assisted recording technology such as HAMR is employed, to prevent or reduce oxidative decomposition in an oxygen-containing atmosphere and maintain high heat resistance in the oxygen-containing atmosphere is attained by a fluoropolyether compound containing at least one ether bond in a molecule, wherein at least one hydrogen atom bonded to a carbon atom bonded to an oxygen atom of the ether bond in the molecule is substituted with fluorine.

(Per)fluoropolyether polymers comprising a (per)fluoropolyether chain having two ends, wherein one or both ends comprise one or more zwitterionic groups at one or both polymer ends, methods for their manufacture and uses thereof are herein disclosed. The polymers can be used in particular for protecting materials in contact with biological fluids or fluids containing biological material from contamination by organic compounds therein contained.