C08L89/06

System and Methods For Sealing a Channel In Tissue
20230054776 · 2023-02-23 ·

A system for performing a minimally invasive percutaneous procedure comprises a medical device comprising a hydrogel delivery needle (4) with a tip and a hydrogel outlet (6), an injectable, shear-thinning, self-healing viscoelastic hydrogel that exhibits a storage modulus (G′) of at least 600 Pa, and a tan δ (G"/G′) from 0.1 to 0.6 in dynamic viscoelasticity measured by a rheometer at 1 Hz and 1% strain rate at 25° C. The system may also comprise a coaxial cannula (2) having a lumen configured for receipt of the hydrogel delivery needle (4), wherein the hydrogel delivery needle comprises an adjustable positioning mechanism (8) configured to limit the advancement depth of the hydrogel delivery needle through the coaxial cannula to a predetermined depth distal to a distal-most end of the coaxial cannula.

TURKEY COLLAGEN HYDROLYSATES AND METHODS OF MAKING

A turkey collagen hydrolysate composition is prepared from turkey collagen sources, wherein the composition has: a protein concentration of from about 80 wt % to 100 wt %; a protein molecular weight distribution wherein from about 80% to 100% of the protein in the turkey collagen hydrolysate composition has a molecular weight of from about 500 to about 15,000 Daltons; a protein solubility of from about 97% to 100% at a pH selected from the group consisting of pH 7.0, pH 3.4, pH 5, and all of pH 7.0, pH 5, and pH 3.4; and a protein amino acid content of 3 to 25 glycine (g/100 g sample), 0.5 to 15 hydroxyproline (g/100 g sample), 1 to 18 proline (g/100 g sample), 0.02 to 4 taurine (g/100 g sample), and 0.05 to 3 tryptophan (g/100 g sample). Methods of preparing turkey collagen hydrolysate compositions are described.

COMPOSITION AND METHODS FOR CULTURING RETINAL PROGENITOR CELLS
20220364049 · 2022-11-17 ·

The present invention provides a scaffold for culturing retinal tissue comprising an amount of gelatin, an amount of chondroitin sulfate, an amount of hyaluronic acid, wherein the amount of gelatin, chondroitin sulfate, and hyaluronic acid are prepared into a three-dimensional monolith, wherein the monolith is sectioned into planar sheets, and an amount of laminin-521.

COMPOSITION AND METHODS FOR CULTURING RETINAL PROGENITOR CELLS
20220364049 · 2022-11-17 ·

The present invention provides a scaffold for culturing retinal tissue comprising an amount of gelatin, an amount of chondroitin sulfate, an amount of hyaluronic acid, wherein the amount of gelatin, chondroitin sulfate, and hyaluronic acid are prepared into a three-dimensional monolith, wherein the monolith is sectioned into planar sheets, and an amount of laminin-521.

BIOLOGICAL MUCOUS MEMBRANE MODEL AND METHOD OF EVALUATING RETENTION OF MUCOUS MEMBRANE PROTECTIVE AGENT
20220365056 · 2022-11-17 · ·

The present invention provides a biological mucous membrane model having high reproducibility of the evaluation result of the retention that is obtained in a case where a mucous membrane protective agent is applied to the mucous membrane of the living body, in a case where the mucous membrane protective agent such as an oral mucous membrane protective agent is applied; and a method of evaluating retention of a mucous membrane protective agent. The biological mucous membrane model according to the embodiment of the present invention has a hydrogel layer, a lipid-containing layer containing a lipid, which is disposed on the hydrogel layer and has through-holes along in a thickness direction, and a hydrophilic polymer layer disposed on the lipid-containing layer in this order.

ANISOTROPIC CONDUCTIVE FILM INCLUDING LIQUID METAL, METHOD FOR MANUFACTURING THE SAME AND DISPLAY DEVICE USING THE SAME

The present disclosure relates to an anisotropic conductive film capable of electrode bonding even at a low temperature and maintaining excellent conductivity and flexibility, a manufacturing method thereof, and a display device using the same. The anisotropic conductive film contains conductive microcapsules including a liquid metal in a binder layer.

ANISOTROPIC CONDUCTIVE FILM INCLUDING LIQUID METAL, METHOD FOR MANUFACTURING THE SAME AND DISPLAY DEVICE USING THE SAME

The present disclosure relates to an anisotropic conductive film capable of electrode bonding even at a low temperature and maintaining excellent conductivity and flexibility, a manufacturing method thereof, and a display device using the same. The anisotropic conductive film contains conductive microcapsules including a liquid metal in a binder layer.

High-strength and tear-resistant leather materials and methods of manufacture

A leather substrate formed from waste leather and its method of production, particularly a leather substrate made up substantially of a collagen fibril matrix.

Shunt for draining ocular fluid

A shunt for draining ocular fluid of one embodiment includes a tubular body formed of a mesh material including bioactive glass fiber and collagen, the tubular body including an implantation member and a conduit through the implantation member. The implantation member and the conduit are formed integrally. Other embodiments are also contemplated.

Shunt for draining ocular fluid

A shunt for draining ocular fluid of one embodiment includes a tubular body formed of a mesh material including bioactive glass fiber and collagen, the tubular body including an implantation member and a conduit through the implantation member. The implantation member and the conduit are formed integrally. Other embodiments are also contemplated.