Devices for magnetic 3d culture are described including magnetic lids/bases for single Petri plates and adjustable height cap for same. Similar devices for multi-magnet culture plates wherein multiwell plates have all adjacent magnets orientated in the opposite polarity, and methods of making same.

A system for analyzing and sorting of petri dishes comprising an analysis tool, a control unit, a first elevator movable along a first elevator axis, a conveyor with a conveyor plane, and at least one carrier built to carry the petri dishes along a carrier axis. The analysis tool is built to assign information to the petri dish, and in case of a first information assigned to the petri dish the control unit is built to move the first elevator into a carrier position, wherein, as soon as the first elevator reaches the carrier position, the control unit is built to move a substantially flat first plate along the first elevator axis from a first neutral position located in the conveyor plane into a first transfer position.

The present invention relates to systems and methods involving interconnected plate components, including bases, lids and covers, interconnected in a manner such that a continuous strip of each component is prepared. The continuous strips may be stored as rollstock in a reel style. The physical properties of each continuous strip allow the base, lid and/or cover to include means for positive control. In one embodiment, the continuous strip of bases is advanced and processed through an automated system with positive control, and remains in the form of a continuous strip until agar in the bases is cured, at which time the bases are singulated. When a lid is applied to a base using methods described herein, an airtight seal is formed improving the quality of culture media used in testing.

The invention relates to portable incubation device comprising a device housing (14) accommodating an incubation chamber housing (3) defining an incubation chamber (9) with an opening (4) together with a feed system (1) and a temperature control system of the heating module (2), characterised in that in the incubation chamber (9) there is at least one heating system (6) comprising at least one heating module (7), preferably two, wherein on the heating system (6) there is a supported a frame (10) supporting a culturing dish (11), and wherein the temperature control system of the heating module (2) provides continuous real time regulation of the desired incubation temperature in the incubation chamber (9).

A cell cultivation apparatus for cultivating microorganisms and growing cells at high density is provided. The apparatus includes a membrane comprising multiple surface features on a first side of the membrane for cell placement. The surface features comprising one or more compartments within which a cell can be located. The membrane includes a material that is at least partially permeable to gas. A second side of the membrane defines a gas region. The second side of the membrane is separated from the first side of the membrane by the membrane. The apparatus further includes a media region for receiving media. The compartments are configured to at least partially reduce media flow shear forces on one or more cells in the compartments. The surface features may be ridges, protrusions, fins, wells, and/or posts.

A holder (10) receives and stores laboratory vessels for samples, microorganisms, cell cultures or the like, with a housing (14), and at least one receptacle (20) for the laboratory vessels. The receptacle (20) extends along a loading axis (L) in the housing (14) and is configured such that the laboratory vessels can be introduced into the receptacle (20) and can be stacked on top of each other therein, wherein the receptacle (20) in the housing (14) has a loading opening (20a) to permit loading. On an underside (18) arranged remote from the loading opening (20a), the receptacle (20) has an unloading opening (20b), which can be closed by means of a closure mechanism (38) arranged in the housing (14). The closure mechanism (38) is provided with a slide (40, 42), via which the slide (40, 42) is movable to the unloading opening (20b) to permit closure and is movable from the unloading opening (20b) to an opening position to permit opening.

The invention relates to a method for producing at least one closed region on a carrier surface of a carrier, wherein the method comprises the following steps: a. adding a first fluid comprising at least one cell and/or at least one particle to the carrier surface and b. adding a second fluid, wherein the second fluid is immiscible with the first fluid and at least partially covers the first fluid and c. acquiring at least one item of cell information and/or of at least one item of particle information and d. producing the closed region on the basis of the at least one acquired item of cell information and/or the at least one acquired item of particle information.

A cell sheet-forming member provided with a surface for forming a cell sheet, wherein the surface comprises a plurality of flat parts and a plurality of concavo-convex parts. Each flat part has a shape extending along a first direction and the plurality of the flat parts are aligned along a second direction intersecting with the first direction over the entire surface. Either of convex parts or concave parts have a stepped structure and individual concave and convex parts include a plurality of the stepped structures which fill gaps between flat parts adjacent to each other, wherein the pitch of said stepped structures is from 100 nm to 10 μm inclusive.

Peel plates and plate assemblies are shown and described. In one embodiment, a peel plate assembly includes a semi-rigid plate, a removable cover seal, and an adhesive to provide a moisture vapor barrier. In particular embodiments, the moisture vapor barrier provides less than about one pound peel adhesion and a stiffness for reapplication without wrinkling. The result is a peel plate, assembly, and method for the enumerating a microorganism, when present, in a sample.

A corneal tissue culture system and a corneal tissue culture method for increasing corneal endothelial cell density, healing of damaged corneal endothelial cell, and stimulating corneal endothelial cell proliferation are disclosed. The corneal tissue culture system comprises a tissue culture medium and a tissue culture dish to reduce metabolic pressure and reduce corneal tissue edema.