A controlling system is provided for operating an examination system configured for microscopic examination of a sample. The examination system includes a microscope, an incubation environment conditioning unit connected to the microscope, and a user interface. The examination system provides an incubation mode in which a sample chamber is incubated by supplying an incubation atmosphere generated by the incubation environment conditioning unit. The controlling system is configured to receive a target setpoint of at least one examination parameter upon user input via the user interface, select, based on the received at least one target setpoint, predefined adjustment setpoints for at least one incubation environment parameter of the incubation mode and for at least one microscope parameter, and operate the incubation environment conditioning unit and the microscope based on the selected adjustment setpoints.

Provided is a reaction apparatus for comprehensively measuring biodegradability of a material, comprising a device frame, an electrical control cabinet and a reaction chamber monomer. The upper side of the reaction chamber monomer is a reaction chamber body, and the lower part is a material receiving trolley. The top of the reaction chamber body is sealed by a chamber cover. A side wall is pasted with an electric heating plate and a thermal insulation cotton. A stirring paddle is arranged inside. An air inlet and an air outlet are respectively provided on a front and a rear wall. A discharging mechanism is located below. The electrical control cabinet separately controls the reaction conditions of each reaction chamber monomer. The present invention further relates to a use method thereof, which can realize the biodegradability evaluation in such three aspects as material degradation rate, disintegration rate and ecological non-toxicity test.

An apparatus, that relates to the field of in vitro fertilization, is provided for the combined incubation and vitrification of a biological material. The apparatus can be configured to allow for automatic incubation and vitrification of a viable biological material. Thereby predetermined protocols for handling the biological material can be performed precisely and accurately thus avoiding errors and deviations from the intended protocol, as caused by manual human intervention.

A cell culture apparatus is provided, including a storage tank including one or a plurality of cell culture units, in which the cell culture unit includes a culture chamber having an inner surface-side space in which a culture solution is stored, a permeable membrane having a first surface to which cells are adherable and a second surface opposite to the first surface, the first surface facing the inner surface-side space, a culture solution storage chamber that stores the culture solution, a culture solution introduction flow path that introduces the culture solution in the culture solution storage chamber to the inner surface-side space, and a culture solution discharge flow path that sends, to the culture solution storage chamber, the culture solution which permeates through the membrane from the inner surface-side space and flows into an outer surface-side space that the second surface of the membrane faces.

A bag assembly for use with a heat exchanger includes a flexible bag having of one or more sheets of polymeric material, the bag having a first end that bounds a first compartment and an opposing second end that bounds a second compartment, a support structure being disposed between the first compartment and the second compartment so that the first compartment is separated and isolated from the second compartment. A first inlet port, a first outlet port, and a first drain port are coupled with the flexible bag so as to communicate with the first compartment. A second inlet port, a second outlet port, and a second drain port are coupled with the flexible bag so as to communicate with the second compartment.

Incubators including an enclosure with an internal chamber configured to support a cell culture plate comprising a plurality of wells are disclosed. The enclosure includes a plurality of openings configured to allow access to the wells. The incubators include a sealing element configured to seal the plurality of openings in the enclosure. The sealing element comprises a plurality of openings corresponding to at least a subset of the plurality of openings in the enclosure. Access to the internal chamber can be provided by aligning the plurality of openings in the sealing element with the plurality of openings in the enclosure. Methods for using the incubators are also provided.

A cell observation system according to the present invention includes: a first image-acquisition device disposed in an incubator and acquires a first image of cells in a culturing vessel; a second image-acquisition device disposed outside the incubator; a processing device connected to the first image-acquisition device and the second image-acquisition device; and a display displays at least a region of the first image, as well as the second image. The second image-acquisition device includes a second image-acquisition unit that acquires a second image of the interior of the culturing vessel, that removed from the incubator. The processing device extracts target cells in the first image, calculates positions at which the extracted target cells are present and stores the positions in the memory, and causes the display to display the positions at which the target cells are present in a superimposed manner on an indication indicating the culturing vessel.

The disclosure relates to methods, systems and compositions for use in the production of milk. More specifically, the disclosure is directed to systems, compositions and methods for in-vitro production of milk using an array of mammary organoids seeded on tertiary-branched, resilient duct scaffolding.

Cell culture systems and methods provide improved immunotherapeutic product manufacturing with greater scalability, flexibility, and automation. Cell culture systems are configured with interchangeable cartridges, allowing versatility and scalability. Systems are configured to have multiple connected cell culture chambers, which allows parallel processing of different types of cells. Gas-impermeable cell culture chambers and methods for generating cells in closed systems prevent contamination and user error. Methods for recycling cell culture medium provide additional efficiencies.

Provided herein are systems and methods for preserving and transporting tissues for transplantation. In particular, tissue to be implanted is encapsulated in an alginate gel, which is exposed to culture medium to improve cell viability and suppress inflammatory factors during long-term storage and transport.