C12N9/0093

PARACOCCUS AMINOVORANS BM109 STRAIN AND USES THEREOF
20250186511 · 2025-06-12 · ·

The present invention provides a Paracoccus aminovorans BM109 strain (Accession number KCTC 15059BP) having excellent removal of trimethylamine (TMA) or trimethylamine N-oxide (TMAO), and a pharmaceutical composition for preventing or treating diseases caused by TMA or TMAO, a health functional food composition for preventing or improving diseases caused by TMA or TMAO, and a feed composition for preventing or improving diseases caused by TMA or TMAO, including the strain as an active ingredient.

BIOTECHNOLOGICAL PRODUCTION OF BISUCABERINS, DESFERRIOXAMINES AND ANALOGS THEREOF

The present invention relates to a recombinant microbial cell for producing at least one compound having structural Formula III from at least one simple carbon source:

##STR00001## wherein the simple carbon source is selected from the group consisting of glucose, sucrose, xylose, arabinose, mannose and glycerol; and wherein the cell comprises a further genetic modification to increase production of L-lysine in the cell from at least one of the simple carbon sources.

APPLICATIONS OF O2-INSENSITIVE FORMATE DEHYDROGENASE

Disclosed are methods and apparatuses utilizing an O.sub.2-insensitive FDH2 from the sulfate-reducing bacterium (SRB) Desulfovibrio vulgaris Hildenborough (DvH). The O.sub.2-insensitive FDH2 may be applied to a biofuel cell for generating electricity and generating hydrogen peroxide. The biofuel cell can also be applied to wearable or implantable devices as a power source. The O.sub.2-insensitive FDH2 can also be used in other applications not applying a fuel cell, such as hydrogen peroxide generation, a formate testing kit, or carbon capture applications.

RECOMBINANT MICROORGANISMS THAT CATABOLIZE LIGNIN AROMATICS AND METHODS OF USING SAME

Recombinant microorganisms that catabolize lignin aromatics, such as -5 linked lignin aromatics, and methods of using same to catabolize the lignin aromatics.

Variant dihydrodipicolinate reductase polypeptide and method of producing L-threonine using the same

The present disclosure relates to a variant polypeptide having attenuated dihydrodipicolinate reductase activity and a method of producing L-threonine using the same.

GENETICALLY MODIFIED MICROORGANISM FOR PRODUCING 3-HYDROXYADIPIC ACID AND/OR Alpha-HYDROXYADIPIC ACID, AND METHOD FOR PRODUCING CHEMICAL PRODUCT

Disclosed is a novel genetically modified microorganism showing improved yields of 3-hydroxyadipic acid and/or -hydromuconic acid. The genetically modified microorganism is a microorganism having an ability to produce 3-hydroxyadipic acid and/or -hydromuconic acid, in which the reaction to generate malic acid from oxaloacetic acid is enhanced, and the reaction to generate acetyl-CoA from pyruvic acid is enhanced. In addition, the reaction to generate carbon dioxide from formic acid is enhanced.

Modified polypeptide of meso-diaminopimelate dehydrogenase and polynucleotide encoding the modified polypeptide

The present disclosure relates to a modified polypeptide, in which the activity of meso-diaminopimelate is weakened, and a method for producing L-threonine using the same.

Gene duplications for crabtree-warburg-like aerobic xylose fermentation

An engineered yeast strain capable of efficient fermentation of xylose to ethanol, and methods of making and using the strain, are provided.