A reagent composition for use as a first reagent composition in a method of quantifying a small dense LDL cholesterol (sdLDL-C) in a sample, the method including causing the first reagent composition to react to the sample, and after the causing the first reagent composition to react to the sample, causing a second reagent composition for quantifying the sdLDL-C to react, thereby quantifying cholesterol in a remaining lipoprotein, the reagent composition includes a nonionic surfactant and has cholesterol esterase activity, cholesterol oxidase activity, and sphingomyelinase activity, and a contact angle between the reagent composition and a polyethylene terephthalate (PET) base material is equal to or more than 63.0 and equal to or less than 67.0.

A reagent composition for use as a first reagent composition in a method of quantifying a small dense LDL cholesterol (sdLDL-C) in a sample, the method including causing the first reagent composition to react to the sample, and after the causing the first reagent composition to react to the sample, causing a second reagent composition for quantifying the sdLDL-C to react, thereby quantifying cholesterol in a remaining lipoprotein, the reagent composition includes a nonionic surfactant and has cholesterol esterase activity, cholesterol oxidase activity, and sphingomyelinase activity, and a contact angle between the reagent composition and a polyethylene terephthalate (PET) base material is equal to or more than 63.0 and equal to or less than 67.0.

Sarcoidosis is a multisystem disease characterized by granulomatous inflammation in affected organs. The present invention discloses kits and a system for a blood test using mycobacterial catalase-peroxidase that has a high positive predictive value for confirming a diagnosis of sarcoidosis.

Sarcoidosis is a multisystem disease characterized by granulomatous inflammation in affected organs. The present invention discloses kits and a system for a blood test using mycobacterial catalase-peroxidase that has a high positive predictive value for confirming a diagnosis of sarcoidosis.

Methods for quantitating viral capsids and/or polynucleotides contained therein using a charged biopolymer-loaded biosensor are provided. The signals indicative of binding of molecules (such as polynucleotides or viral capsids) to the biosensor can be measured by bio-layer interferometry (BLI). The amount of viral capsids can be calculated based on signals indicative of binding of the viral capsids to the biosensor. The empty/full viral capsid ratio in a viral sample can be calculated based on the amount of the viral polynucleotides and/or the binding kinetics of the biosensor to the viral capsids or the polynucleotides.

Methods for quantitating viral capsids and/or polynucleotides contained therein using a charged biopolymer-loaded biosensor are provided. The signals indicative of binding of molecules (such as polynucleotides or viral capsids) to the biosensor can be measured by bio-layer interferometry (BLI). The amount of viral capsids can be calculated based on signals indicative of binding of the viral capsids to the biosensor. The empty/full viral capsid ratio in a viral sample can be calculated based on the amount of the viral polynucleotides and/or the binding kinetics of the biosensor to the viral capsids or the polynucleotides.

A reagent composition containing an anionic surfactant, in which the reagent composition is used as a first reagent composition in a method for quantifying a sdLDL-C in a sample, the method including acting the first reagent composition on a sample, and subsequently acting a second reagent composition for quantifying the sdLDL-C to quantify cholesterol in a remaining lipoprotein, the reagent composition has cholesterol esterase activity and cholesterol oxidase activity, and also has at least one activity selected from the group made of peroxidase activity and catalase activity, and a contact angle between the reagent composition and a polyethylene terephthalate (PET) base material is equal to or more than 65 and equal to or less than 77.

A reagent composition containing an anionic surfactant, in which the reagent composition is used as a first reagent composition in a method for quantifying a sdLDL-C in a sample, the method including acting the first reagent composition on a sample, and subsequently acting a second reagent composition for quantifying the sdLDL-C to quantify cholesterol in a remaining lipoprotein, the reagent composition has cholesterol esterase activity and cholesterol oxidase activity, and also has at least one activity selected from the group made of peroxidase activity and catalase activity, and a contact angle between the reagent composition and a polyethylene terephthalate (PET) base material is equal to or more than 65 and equal to or less than 77.