Patent classifications
C12R2001/225
BIOPROTECTIVE LACTIC ACID BACTERIA WITH LOW POSTACIDIFICATION
The present invention is in the field of dairy technology. It relates to methods for producing fermented milk products, characterized the bacterium Lactobacillus rhamnosus DSM 33515 or mutants obtainable therefrom is used. Lactobacillus rhamnosus bacteria DSM 33515 has low post-acidification in fermented milk products and can provide antimicrobial effects. The invention also provides Lactobacillus rhamnosus DSM 33515 or mutants obtainable therefrom as well as related compositions.
NEW PROBIOTIC COMPOSITION FOR PREVENTION OF BACTERIAL VAGINOSIS
The present invention relates to a mixture of strains of Lactobacillus crispatus, which mixture comprises strains that have a different carbohydrate degradation profile, comprising at least one strain of L. crispatus that is able to degrade glycogen, and at least one strain of L. crispatus that is able to degrade lactose. Such a mixture is of use in the treatment or prevention of bacterial vaginosis, preferably to decrease recurrence of bacterial vaginosis after treatment with antibiotics.
PROBIOTIC-ENCAPSULATING GUM ARABIC COMPOSITE FIBER/CAPSULE, PREPARATION METHOD AND APPLICATION THEREOF
A probiotic-encapsulating gum Arabic (GA) composite fiber/capsule, including: lactic acid bacteria and an electrospun fiber or electrosprayed capsule, where the lactic acid bacteria are encapsulated in the electrospun fiber or electrosprayed capsule by electro-hydro dynamics (EHD) technology. The electrospun fiber or electrosprayed capsule is prepared by compounding a polymer matrix with GA, and the polymer matrix is polyvinyl alcohol (PVOH), polyvinylpyrrolidone (PVP), whey protein concentrate (WPC) or maltodextrin (MD). A preparation method and an application of the composite fiber/capsule are also provided.
STRAIN OF LACTOBACILLUS PARACASEI FOR PROMOTING HAIR GROWTH, HAIR PRODUCT HAVING SAME, AND USE THEREOF
A strain of Lactobacillus paracasei for promoting hair growth, a hair product having same, and a use thereof are disclosed. The strain of Lactobacillus paracasei is Lactobacillus paracasei GMNL-653, which was deposited at the China Center for Type Culture Collection in Wuhan, China on Apr. 25, 2016 under an accession number CCTCC NO. M 2016226.
PASTA SOURDOUGH CULTURES AND METHODS OF MAKING SAME
The present disclosure relates to the preparation and maintenance of sourdough cultures that can be used to prepare pasta. The disclosure describes the identification of specific fermentation conditions that reliably maintain lactate-utilizing lactobacilli as dominant members of the microbiota by traditional methods. A crucial difference between known processes and the inventive process is that the conditions of the inventive fermentation process naturally select for several species of microorganisms, including Levilactobacillus koreensis and Levilactobacillus parabrevis. Specifically, the cold fermentation favors growth of these organisms and thereby produces more acetic acid than lactic acid in the sourdough.
PROTECTIVE BARRIER COMPOSITIONS, AND USES THEREOF
The subject invention provides compositions and methods of enhancing the barrier function of surfaces and/or objects using biochemical-producing microbes and/or byproducts synthesized by the microbes. Preferred embodiments of the invention provide compositions, and the methods of using the same, comprising a Lactobacillus sp., and/or bioactive extracts thereof, derived from human microbiota and capable of growing in biofilm phenotype.
EXOPOLYSACCHARIDE OF LACTIC ACID BACTERIUM AND USE THEREOF
An exopolysaccharide of a lactic acid bacterium derived from a fig and belonging to Lactobacillus paracasei includes a neutral polysaccharide having a structure in which N-acetylglucosamines are linked with each other via α-1,6 bond, has a hyaluronidase inhibitory, and is therefore useful in a food and drink, a medicine, a feed, a cosmetic and the like exerting an antiallergy effect.
COMPOSITION FOR REGULATING STEM CELL FUNCTION COMPRISING THE GENUS LACTOBACILLUS BACTERIA-DERIVED EXTRACELLULAR VESICLES (EVS) AS AN ACTIVE INGREDIENT
Provided are a composition for regulating stem cell function comprising the genus Lactobacillus bacteria-derived extracellular vesicles as an active ingredient, and a method for regulating a stem cell function using the same, wherein the genus Lactobacillus bacterial-derived extracellular vesicles have the effect of greatly improving the proliferation of stem cells, and the extracellular vesicles are naturally secreted from a symbiotic the genus Lactobacillus strain in human tonsillar tissue and are human-friendly and natural substances, and thus can be used in various research fields by promoting the proliferation of aged stem cells with minimal toxicity and side effects.
NOVEL LACTIC ACID BACTERIA AND USE THEREOF
The present invention relates to the novel lactic acid bacteria Lactobacillus mucosae and Bifidobacterium longum, and specifically, to a composition comprising the novel lactic acid bacteria, the composition enabling the inhibition of the expression of the p16 protein, which is an aging factor, and the inhibition of inflammatory factors, thereby being useful in preventing and treating memory impairment, learning disabilities or mental disorders, and in preventing and treating inflammatory diseases.
Pathway integration and expression in host cells
Provided herein are methods for integrating a gene of interest into a chromosome of a host cell. In some embodiments, the methods include introducing into a host cell a first plasmid comprising a transposase coding sequence and a donor sequence, which includes a selectable marker coding sequence flanked by a first and a second lox site and is itself flanked by inverted repeats recognized by the transposase. Following transposase-mediated chromosomal integration of the donor sequence into the host cell, a second plasmid is introduced, which comprises the gene of interest and a second selectable marker coding sequence, both flanked by a first and a second lox site. The gene of interest is chromosomally integrated into the host cell by recombinase-mediated cassette exchange (RMCE) between the donor sequence and the second plasmid via Cre-/cuc recombination. Further provided herein are host cells, vectors, and methods of producing a product related thereto.