Patent classifications
C12Y101/01049
PUTRESCINE-PRODUCING MICROORGANISM AND METHOD OF PRODUCING PUTRESCINE USING THE SAME
The present disclosure relates to a putrescine-producing microorganism of the genus Corynebacterium, and a method of producing putrescine using the same.
Pregabalin immunoassays
Compounds and methods for use in detecting pregabalin in a sample suspected of containing pregabalin are disclosed. Pregabalin derivatives are described for producing pregabalin conjugates. A pregabalin-immunogenic carrier conjugate may be used as an immunogen for the preparation of an anti-pregabalin antibody. A pregabalin-detectable label conjugate may be used in a signal producing system in pregabalin assays.
Compositions and methods for rapid and dynamic flux control using synthetic metabolic valves
This invention relates to metabolically engineered microorganisms, such as bacterial and or fungal strains, and bioprocesses utilizing such strains. These strains enable the dynamic control of metabolic pathways, which can be used to optimize production. Dynamic control over metabolism is accomplished via a combination of methodologies including but not limited to transcriptional silencing and controlled enzyme proteolysis. These microbial strains are utilized in a multi-stage bioprocess encompassing at least two stages, the first stage in which microorganisms are grown and metabolism can be optimized for microbial growth and at least one other stage in which growth can be slowed or stopped, and dynamic changes can be made to metabolism to improve the production of desired product, such as a chemical or fuel.
MULTI-COMPONENT DETERGENTS OR CLEANSERS CONTAINING A QUINONE OXIDOREDUCTASE
Detergents or cleansers may include at least one quinone oxidoreductase, an NAD(P)H cofactor, and a first substrate for the quinone oxidoreductase. The quinone oxidoreductase may be spatially separated from the NAD(P)H cofactor and/or first substrate. The detergent or cleanser may also include at least one inhibitor of the quinone oxidoreductase. A method for washing textiles or automatic dishwashing using this detergent or cleanser is also disclosed.
Transgenic plants with enhanced traits
This disclosure provides transgenic plants having enhanced traits such as increased yield, increased nitrogen use efficiency and enhanced drought tolerance; propagules, progeny and field crops of such transgenic plants; and methods of making and using such transgenic plants. This disclosure also provides methods of producing hybrid seed from such transgenic plants, growing such seed and selecting progeny plants with enhanced traits. Also disclosed are transgenic plants with altered phenotypes which are useful for screening and selecting transgenic events for the desired enhanced trait.
Multi-substrate metabolism for improving biomass and lipid production
The present application relates to methods to improve biomass or lipid production in a microorganism from one or more fatty acid and one or more simple carbon co-substrates. Produced lipids may include unsaturated C.sub.6-C.sub.24 fatty acids, alcohols, aldehydes, and acetates which may be useful as final products or precursors to insect pheromones, fragrances, flavors, and polymer intermediates. The application further relates to recombinant microorganisms modified for improved production of biomass or lipid, or improved lipid selectivity. Also provided are methods of producing one or more lipid using the recombinant microorganisms, as well as compositions comprising the recombinant microorganisms and/or optionally one or more of the product lipid.
COMPOSITIONS AND METHODS FOR THE PRODUCTION OF PYRUVIC ACID AND RELATED PRODUCTS USING DYNAMIC METABOLIC CONTROL
The present disclosure is related to genetically engineered microbial strains and related bioprocesses for the production of pyruvate and related products. Specifically, the use of dynamically controlled synthetic metabolic valves to reduce the activity of enzymes known to contribute to pyruvate synthesis, leads to increased pyruvate production in a two-stage process rather than a decrease in production.
Homogenous immunoassay with compensation for background signal
Homogeneous immunoassays that allow for compensation of background signals inherent in samples and reagents. The use of homogeneous immunoassays for the detection of the presence or amount of symmetrical Dimethyl Arginine (SDMA) in biological samples. Reagents and kits for conducting the assays.
MICROORGANISM OF THE GENUS CORYNEBACTERIUM FOR PRODUCING L-AMINO ACID AND METHOD FOR PRODUCING L-AMINO ACID USING THE SAME
The present disclosure relates to a microorganism of the genus Corynebacterium producing L-amino acid, a method for producing L-amino acid using the same, use of L-amino acid production, and a composition for producing L-amino acid.
Production of Activated TDP-Deoxysugars in Recombinant Microorganisms
The invention provides compositions and methods for the production of TDP-deoxysugars.