The present invention relates to a cellular composition, more particularly a composition comprising a serotonin receptor-expressing cells that have been exposed to a serotonin receptor agonist and consequently stimulated, for use in the treatment of a disease, disorder or condition; a method of use; and a method for preparing such a composition.

The present invention relates to the field of cancer therapeutics and treatment of cancer. In particular, it relates to a method for treating and/or preventing a natural AHR ligand-dependent cancer comprising administering to a subject suffering from said cancer a therapeutically effective amount of an AHR inhibitor. Moreover, contemplated is a AHR inhibitor for use in treating and/or preventing a natural AHR ligand-dependent cancer.