Patent classifications
C
CHEMISTRY; METALLURGY
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C12
BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
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C12Y
ENZYMES
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207/00
Transferases transferring phosphorus-containing groups (2.7)
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C12Y207/07
Nucleotidyltransferases (2.7.7)
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C12Y207/07041
Phosphatidate cytidylyltransferase (2.7.7.41), i.e. CDP-diacylglycerol synthase
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C12Y207/07041

TREATMENT OF CANCERS HAVING A DRUG-RESISTANT MESENCHYMAL CELL STATE
20260125683 · 2026-05-07 · ·

The subject matter disclosed herein is generally directed to methods of treating a tumor capable of an epithelial-to-mesenchymal transition (an EMT cancer) by targeting the mesenchymal cell state. Disclosed are novel gene dependencies in the mesenchymal cell state. Also, disclosed are novel drugs that target the mesenchymal cell state.