A plastic material for extended release of a bio-active agent, the plastic material comprising a structural polymer, at least one bio-active ingredient embedded within the structural polymer as solid islands, a liquid binding material embedded within the structural polymer as granules, and a carrier liquid absorbed within the liquid-absorbent material. The carrier liquid may be sufficiently non-compatible with the structural polymer so that at least a portion of the carrier liquid is released from the liquid-absorbent material through the structural polymer to an outer surface of the plastic material over a period of time, such as a week or more, a month or more, or about three months. The bio-active agent comprised in the at least one bio-active ingredient may be sufficiently soluble in the carrier liquid at room or body temperature so that the carrier liquid released to the outer surface comprises the bio-active agent in solution.

The present invention relates to a collar for non-human animals, preferably for companion animals, comprising a polymeric matrix and a lipid extract comprising sphingomyelins. It also refers to the collar for use as a medicine, particularly for use as an adjuvant and for use in the treatment or prevention of atopic dermatitis or allergic dermatitis, as well as in restoring the integrity of the skin during or after an atopic dermatitis or an allergic dermatitis, increasing the hydration and flexibility of the skin, facilitating skin regeneration or reducing itching of the skin.

The invention relates to a refillable device (1) for spraying an active substance, comprising a reservoir (2) containing at least one active substance, said device being equipped with a piezoelectric spraying mechanism (6). The device is attached to or in the collar of an animal. The invention also relates to the use of said device for spraying an active substance in a controlled manner from a distance in a desired direction. Said device can be used multi-directionally independently of the movements of the animal.

The disclosure provides an insecticide formulation, comprising: i) a neonicotinoid optionally together with a pyrethroid; ii) an insect growth regulator; and iii) a filling agent together with a plasticizer.

Insect repellant articles and the use of the insect repellant articles. In accordance with certain embodiments, the insect repellant article comprises scent releasing component capable of deterring insects and/or other pests. The insect repellant articles are particularly useful in repelling insects such as bees, which can cause allergic reactions in pets or other animals.

An pet spray training system is provided. The system includes a sound, vibration or motion sensor that is configured to generate electrical signals in response to an occurrence. The system may include a filter, which is tuned to recognize a dog barking event, and generate an electrical signal in response to recognizing an input signal indicative of a dog's bark. The system further includes a removably pressurized gas reservoir that holds a deterrent fluid under pressure. The system additionally comprises a motor module configured to rotate a shaft in response to the electrical signal from the filter. The canister has a spray nozzle for releasing fluid that affects the dog's senses. In response to rotating the shaft, the spray nozzle is depressed.

An extended-release plastic matrix formulation (PMF-ExR) comprising a polyethylene-comprising polymer, a plasticizer, and at least one insecticide as active components is described. The PMF-ExR may be used in the manufacture of a wearable device for treating ectoparasitic infestations.

The automatically attaching collar clasps are installed in an animal bait station. The bait station has an inlet so that when an animal is positioned in the inlet, a male clasp on one side of the inlet automatically converges with a female clasp on the opposite side to the inlet to create a ratcheting connection and thereby secures a collar around the neck of the targeted animal.

A plastic material for extended release of a bio-active agent, the plastic material comprising a structural polymer, at least one bio-active ingredient embedded within the structural polymer as solid islands, a liquid binding material embedded within the structural polymer as granules, and a carrier liquid absorbed within the liquid-absorbent material. The carrier liquid may be sufficiently non-compatible with the structural polymer so that at least a portion of the carrier liquid is released from the liquid-absorbent material through the structural polymer to an outer surface of the plastic material over a period of time, such as a week or more, a month or more, or about three months. The bio-active agent comprised in the at least one bio-active ingredient may be sufficiently soluble in the carrier liquid at room or body temperature so that the carrier liquid released to the outer surface comprises the bio-active agent in solution.

A drug delivery pump includes a dosing chamber (16) for delivering a substance (18) therefrom, pushing apparatus, and a thermal energy source (14) arranged to cause a sufficient change in temperature in a portion of the pushing apparatus so that the pushing apparatus imparts a pushing force against the substance to cause the substance to be delivered from the dosing chamber. A controller (90) controls delivery of the substance from the dosing chamber. A thermal insulator (24) thermally insulates the substance in the dosing chamber from the thermal energy source.